{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699994579327488.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.jinsphys.2010.05.019"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S002219101000168X?httpAccept=text/xml"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S002219101000168X?httpAccept=text/plain"}},{"identifier":{"@type":"PMID","@value":"20576517"}}],"dc:title":[{"@value":"Multiple vitellogenins from the Haemaphysalis longicornis tick are crucial for ovarian development"}],"description":[{"notation":[{"@value":"Ovarian development and egg maturation are crucial processes for the success of reproduction in ticks. Three full-length cDNAs encoding the precursor of major yolk protein, vitellogenin, were obtained from cDNA libraries of the Haemaphysalis longicornis tick and designated as HlVg-1, HlVg-2 and HlVg-3. The HlVg mRNAs were found in fed females with major expression sites in the midgut, fat body and ovary. Native PAGE and Western blot demonstrated that HlVgs in the hemolymph, fat body and ovary of fed females consisted of four major polypeptides. RNAi results showed that HlVg dsRNA-injected ticks obtained lower body weight, egg weight and showed higher mortality of engorged females after blood sucking than control groups. Our results indicate that all HlVgs are essential for egg development and oviposition."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699994579327491","@type":"Researcher","foaf:name":[{"@value":"Damdinsuren Boldbaatar"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994579327493","@type":"Researcher","foaf:name":[{"@value":"Rika Umemiya-Shirafuji"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994579327490","@type":"Researcher","foaf:name":[{"@value":"Min Liao"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994579327488","@type":"Researcher","foaf:name":[{"@value":"Tetsuya Tanaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994579327492","@type":"Researcher","foaf:name":[{"@value":"Xuenan Xuan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994579327489","@type":"Researcher","foaf:name":[{"@value":"Kozo Fujisaki"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00221910"}],"prism:publicationName":[{"@value":"Journal of Insect Physiology"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2010-11","prism:volume":"56","prism:number":"11","prism:startingPage":"1587","prism:endingPage":"1598"},"reviewed":"false","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/","https://www.elsevier.com/legal/tdmrep-license"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S002219101000168X?httpAccept=text/xml"},{"@id":"https://api.elsevier.com/content/article/PII:S002219101000168X?httpAccept=text/plain"}],"createdAt":"2010-06-05","modifiedAt":"2025-09-19","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=DNA,%20Complementary","dc:title":"DNA, Complementary"},{"@id":"https://cir.nii.ac.jp/all?q=Base%20Sequence","dc:title":"Base Sequence"},{"@id":"https://cir.nii.ac.jp/all?q=Ixodidae","dc:title":"Ixodidae"},{"@id":"https://cir.nii.ac.jp/all?q=Molecular%20Sequence%20Data","dc:title":"Molecular Sequence Data"},{"@id":"https://cir.nii.ac.jp/all?q=Gene%20Expression%20Regulation,%20Developmental","dc:title":"Gene Expression Regulation, Developmental"},{"@id":"https://cir.nii.ac.jp/all?q=Vitellogenins","dc:title":"Vitellogenins"},{"@id":"https://cir.nii.ac.jp/all?q=Animals","dc:title":"Animals"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Amino%20Acid%20Sequence","dc:title":"Amino Acid Sequence"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050001338855365888","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"2-Cys peroxiredoxin is required in successful blood-feeding, reproduction, and antioxidant response in the hard tick Haemaphysalis longicornis"}]},{"@id":"https://cir.nii.ac.jp/crid/1050845763336464768","@type":"Article","resourceType":"学術雑誌論文(journal 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