{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699994628112384.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1242/dev.071209"}},{"identifier":{"@type":"URI","@value":"http://journals.biologists.com/dev/article-pdf/139/19/3471/1159752/3471.pdf"}}],"dc:title":[{"@value":"Epithelial-mesenchymal transitions: insights from development"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Epithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that occurs during development and is essential for shaping embryos. Also implicated in cancer, this morphological transition is executed through multiple mechanisms in different contexts, and studies suggest that the molecular programs governing EMT, albeit still enigmatic, are embedded within developmental programs that regulate specification and differentiation. As we review here, knowledge garnered from studies of EMT during gastrulation, neural crest delamination and heart formation have furthered our understanding of tumor progression and metastasis.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699994628112256","@type":"Researcher","foaf:name":[{"@value":"Jormay Lim"}],"jpcoar:affiliationName":[{"@value":"Institute of Molecular Cell Biology, A*STAR, 61 Biopolis Drive, 138673, Singapore."}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994628112384","@type":"Researcher","foaf:name":[{"@value":"Jean Paul Thiery"}],"jpcoar:affiliationName":[{"@value":"Institute of Molecular Cell Biology, A*STAR, 61 Biopolis Drive, 138673, Singapore."},{"@value":"Cancer Science Institute, National University of Singapore, 14 Medical Drive, 117599, Singapore."}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"14779129"},{"@type":"PISSN","@value":"09501991"}],"prism:publicationName":[{"@value":"Development"}],"dc:publisher":[{"@value":"The Company of Biologists"}],"prism:publicationDate":"2012-10-01","prism:volume":"139","prism:number":"19","prism:startingPage":"3471","prism:endingPage":"3486"},"reviewed":"false","url":[{"@id":"http://journals.biologists.com/dev/article-pdf/139/19/3471/1159752/3471.pdf"}],"createdAt":"2012-09-04","modifiedAt":"2022-01-28","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050001335860224896","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1050304183896256000","@type":"Article","resourceType":"学術雑誌論文(journal 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