{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699994775812608.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1111/j.1469-8986.2011.01226.x"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1469-8986.2011.01226.x"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1469-8986.2011.01226.x"}}],"dc:title":[{"@value":"Pupillometry and P3 index the locus coeruleus–noradrenergic arousal function in humans"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>The adaptive gain theory highlights the pivotal role of the locus coeruleus–noradrenergic (LC‐NE) system in regulating task engagement. In humans, however, LC‐NE functional dynamics remain largely unknown. We evaluated the utility of two candidate psychophysiological markers of LC‐NE activity: the P3 event‐related potential and pupil diameter. Electroencephalogram and pupillometry data were collected from 24 participants who performed a 37‐min auditory oddball task. As predicted by the adaptive gain theory, prestimulus pupil diameter exhibited an inverted U‐shaped relationship to P3 and task performance such that largest P3 amplitudes and optimal performance occurred at the same intermediate level of pupil diameter. Large phasic pupil dilations, by contrast, were elicited during periods of poor performance and were followed by reengagement in the task and increased P3 amplitudes. These results support recent proposals that pupil diameter and the P3 are sensitive to LC‐NE mode.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699994775812736","@type":"Researcher","foaf:name":[{"@value":"Peter R. Murphy"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994775812737","@type":"Researcher","foaf:name":[{"@value":"Ian H. Robertson"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994775812609","@type":"Researcher","foaf:name":[{"@value":"Joshua H. Balsters"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994775812608","@type":"Researcher","foaf:name":[{"@value":"Redmond G. O'connell"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00485772"},{"@type":"EISSN","@value":"14698986"}],"prism:publicationName":[{"@value":"Psychophysiology"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2011-07-18","prism:volume":"48","prism:number":"11","prism:startingPage":"1532","prism:endingPage":"1543"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1469-8986.2011.01226.x"},{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1469-8986.2011.01226.x"}],"createdAt":"2011-07-18","modifiedAt":"2023-10-31","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360002216089242368","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Curiosity in old age: A possible key to achieving adaptive aging"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232397855744","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Electrophysiological indices of anterior cingulate cortex function reveal changing levels of cognitive effort and reward valuation that sustain task performance"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142906465408","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Atypical alert state control in adult patients with ADHD: A pupillometry study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013168836418304","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pupillary response reflects attentional modulation to sound after emotional arousal"}]},{"@id":"https://cir.nii.ac.jp/crid/1360302866846353408","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Look into my eyes: What can eye-based measures tell us about the relationship between physical activity and cognitive performance?"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1111/j.1469-8986.2011.01226.x"},{"@type":"CROSSREF","@value":"10.1371/journal.pone.0244662_references_DOI_P27suEKsgZKoGkCYacYMEnGxehi"},{"@type":"CROSSREF","@value":"10.1038/s41598-021-96643-7_references_DOI_P27suEKsgZKoGkCYacYMEnGxehi"},{"@type":"CROSSREF","@value":"10.1016/j.jshs.2023.04.003_references_DOI_P27suEKsgZKoGkCYacYMEnGxehi"},{"@type":"CROSSREF","@value":"10.1016/j.neuropsychologia.2018.06.010_references_DOI_P27suEKsgZKoGkCYacYMEnGxehi"},{"@type":"CROSSREF","@value":"10.1016/j.neubiorev.2018.03.007_references_DOI_P27suEKsgZKoGkCYacYMEnGxehi"}]}