{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699994841110784.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3171/jns.1995.83.1.0056"}},{"identifier":{"@type":"URI","@value":"https://thejns.org/view/journals/j-neurosurg/83/1/article-p56.xml"}},{"identifier":{"@type":"URI","@value":"https://thejns.org/downloadpdf/journals/j-neurosurg/83/1/article-p56.xml"}},{"identifier":{"@type":"PMID","@value":"7782850"}}],"dc:title":[{"@value":"Natural history of intracranial cavernous malformations"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p content-type=\"fine-print\">✓ The authors have reviewed the clinical records of 110 patients with intracranial cavernous malformations diagnosed by histological examination and/or magnetic resonance imaging over a mean follow-up period of 4.71 years. These cases were divided, based on their presentation, into a hemorrhage group, a seizure group, and an incidentally diagnosed group. The rate of subsequent symptomatic bleeding was investigated in relation to age at onset, sex, and location of the initial lesion. A high rate of subsequent symptomatic bleeding episodes was found in the hemorrhage group, especially among younger females. The nonhemorrhagic-onset cases had a very low incidence of bleeding. The outcome was generally good, except in patients with lesions in the basal ganglia and brainstem. These findings will be helpful in planning a rational therapeutic strategy for intracranial cavernous malformations.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699994841110787","@type":"Researcher","foaf:name":[{"@value":"Toyotaka Aiba"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994841110788","@type":"Researcher","foaf:name":[{"@value":"Ryuichi Tanaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994841110786","@type":"Researcher","foaf:name":[{"@value":"Tetsuo Koike"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994841110785","@type":"Researcher","foaf:name":[{"@value":"Shigeki Kameyama"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994841110784","@type":"Researcher","foaf:name":[{"@value":"Norio Takeda"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699994841110789","@type":"Researcher","foaf:name":[{"@value":"Tadashi Komata"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00223085"}],"prism:publicationName":[{"@value":"Journal of Neurosurgery"}],"dc:publisher":[{"@value":"Journal of Neurosurgery Publishing Group (JNSPG)"}],"prism:publicationDate":"1995-07","prism:volume":"83","prism:number":"1","prism:startingPage":"56","prism:endingPage":"59"},"reviewed":"false","url":[{"@id":"https://thejns.org/view/journals/j-neurosurg/83/1/article-p56.xml"},{"@id":"https://thejns.org/downloadpdf/journals/j-neurosurg/83/1/article-p56.xml"}],"createdAt":"2009-06-02","modifiedAt":"2022-05-14","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Adult","dc:title":"Adult"},{"@id":"https://cir.nii.ac.jp/all?q=Intracranial%20Arteriovenous%20Malformations","dc:title":"Intracranial Arteriovenous Malformations"},{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Chi-Square%20Distribution","dc:title":"Chi-Square Distribution"},{"@id":"https://cir.nii.ac.jp/all?q=Adolescent","dc:title":"Adolescent"},{"@id":"https://cir.nii.ac.jp/all?q=Brain%20Neoplasms","dc:title":"Brain Neoplasms"},{"@id":"https://cir.nii.ac.jp/all?q=Incidence","dc:title":"Incidence"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Magnetic%20Resonance%20Imaging","dc:title":"Magnetic Resonance Imaging"},{"@id":"https://cir.nii.ac.jp/all?q=Hemangioma,%20Cavernous","dc:title":"Hemangioma, Cavernous"},{"@id":"https://cir.nii.ac.jp/all?q=Risk%20Factors","dc:title":"Risk Factors"},{"@id":"https://cir.nii.ac.jp/all?q=Seizures","dc:title":"Seizures"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Sex%20Distribution","dc:title":"Sex Distribution"},{"@id":"https://cir.nii.ac.jp/all?q=Child","dc:title":"Child"},{"@id":"https://cir.nii.ac.jp/all?q=Tomography,%20X-Ray%20Computed","dc:title":"Tomography, X-Ray Computed"},{"@id":"https://cir.nii.ac.jp/all?q=Cerebral%20Hemorrhage","dc:title":"Cerebral Hemorrhage"},{"@id":"https://cir.nii.ac.jp/all?q=Follow-Up%20Studies","dc:title":"Follow-Up Studies"},{"@id":"https://cir.nii.ac.jp/all?q=Retrospective%20Studies","dc:title":"Retrospective Studies"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050848249856054400","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Cavernous malformation of the optic chiasm with continuous hemorrhage in a pregnant woman: A case report"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567182508124160","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Symptomatic Brainstem Cavernoma of Elderly Patients: Timing and Strategy of Surgical Treatment. 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