{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699995122931200.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1073/pnas.0407360102"}},{"identifier":{"@type":"URI","@value":"https://pnas.org/doi/pdf/10.1073/pnas.0407360102"}}],"dc:title":[{"@value":"The nonmevalonate pathway supports both monoterpene and sesquiterpene formation in snapdragon flowers"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>\n            Terpenoids, the largest class of plant secondary metabolites, play essential roles in both plant and human life. In higher plants, the five-carbon building blocks of all terpenoids, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate, are derived from two independent pathways localized in different cellular compartments. The methylerythritol phosphate (MEP or nonmevalonate) pathway, localized in the plastids, is thought to provide IPP and dimethylallyl diphosphate for hemiterpene, monoterpene, and diterpene biosynthesis, whereas the cytosol-localized mevalonate pathway provides C\n            <jats:sub>5</jats:sub>\n            units for sesquiterpene biosynthesis. Stable isotope-labeled, pathway-specific precursors (1-deoxy-[5,5-\n            <jats:sup>2</jats:sup>\n            H\n            <jats:sub>2</jats:sub>\n            ]-\n            <jats:sc>d</jats:sc>\n            -xylulose and [2,2-\n            <jats:sup>2</jats:sup>\n            H\n            <jats:sub>2</jats:sub>\n            ]-mevalolactone) were supplied to cut snapdragon flowers, which emit both monoterpenes and the sesquiterpene, nerolidol. We show that only one of the two pathways, the plastid-localized MEP pathway, is active in the formation of volatile terpenes. The MEP pathway provides IPP precursors for both plastidial monoterpene and cytosolic sesquiterpene biosynthesis in the epidermis of snapdragon petals. The trafficking of IPP occurs unidirectionally from the plastids to cytosol. The MEP pathway operates in a rhythmic manner controlled by the circadian clock, which determines the rhythmicity of terpenoid emission.\n          </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380857613063004166","@type":"Researcher","foaf:name":[{"@value":"Natalia Dudareva"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]},{"@id":"https://cir.nii.ac.jp/crid/1380857613063004167","@type":"Researcher","foaf:name":[{"@value":"Susanna Andersson"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]},{"@id":"https://cir.nii.ac.jp/crid/1380857613063004164","@type":"Researcher","foaf:name":[{"@value":"Irina Orlova"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]},{"@id":"https://cir.nii.ac.jp/crid/1380857613063004160","@type":"Researcher","foaf:name":[{"@value":"Nathalie Gatto"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]},{"@id":"https://cir.nii.ac.jp/crid/1380857613063004162","@type":"Researcher","foaf:name":[{"@value":"Michael Reichelt"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]},{"@id":"https://cir.nii.ac.jp/crid/1380857613063004161","@type":"Researcher","foaf:name":[{"@value":"David Rhodes"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]},{"@id":"https://cir.nii.ac.jp/crid/1380857613063004163","@type":"Researcher","foaf:name":[{"@value":"Wilhelm Boland"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]},{"@id":"https://cir.nii.ac.jp/crid/1380857613063004165","@type":"Researcher","foaf:name":[{"@value":"Jonathan Gershenzon"}],"jpcoar:affiliationName":[{"@value":"Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907; and Max Planck Institute for Chemical Ecology, Beutenberg Campus, Hans-Knoell-Strasse 8, D-07745 Jena, Germany"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00278424"},{"@type":"EISSN","@value":"10916490"}],"prism:publicationName":[{"@value":"Proceedings of the National Academy of Sciences"}],"dc:publisher":[{"@value":"Proceedings of the National Academy of Sciences"}],"prism:publicationDate":"2005-01-03","prism:volume":"102","prism:number":"3","prism:startingPage":"933","prism:endingPage":"938"},"reviewed":"false","url":[{"@id":"https://pnas.org/doi/pdf/10.1073/pnas.0407360102"}],"createdAt":"2005-01-04","modifiedAt":"2022-04-12","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360285708100807296","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Interfacial vs Bulk Ozonolysis of Nerolidol"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567912624395520","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Identification of differentially expressed genes during flower opening by suppression subtractive hybridization and cDNA microarray analysis in Eustoma grandiflorum"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576118714832000","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Herbivore‐induced and constitutive volatiles are controlled by different oxylipin‐dependent mechanisms in rice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360869855114441088","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Basal emission rates of isoprene and monoterpenes from major tree species in Japan: interspecies and intraspecies variabilities"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204326849024","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Foliar application of methyl jasmonate does not increase terpenoid accumulation, but weakly elicits terpenoid pathway genes in sandalwood (<i>Santalum album</i> L.) seedlings"},{"@value":"Foliar application of methyl jasmonate does not increase terpenoid accumulation, but weakly elicits terpenoid pathway genes in sandalwood (Santalum album L.) seedlings"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679303560704","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The genetic basis of foliar terpene yield: Implications for breeding and profitability of Australian essential oil crops"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1073/pnas.0407360102"},{"@type":"CROSSREF","@value":"10.5511/plantbiotechnology.14.1009a_references_DOI_4emyFr47WmSdZ8mM8ot0mv0lFQc"},{"@type":"CROSSREF","@value":"10.1021/acs.est.9b00364_references_DOI_4emyFr47WmSdZ8mM8ot0mv0lFQc"},{"@type":"CROSSREF","@value":"10.1111/pce.14126_references_DOI_4emyFr47WmSdZ8mM8ot0mv0lFQc"},{"@type":"CROSSREF","@value":"10.1186/s40645-024-00645-8_references_DOI_4emyFr47WmSdZ8mM8ot0mv0lFQc"},{"@type":"CROSSREF","@value":"10.1016/j.scienta.2009.03.011_references_DOI_4emyFr47WmSdZ8mM8ot0mv0lFQc"},{"@type":"CROSSREF","@value":"10.5511/plantbiotechnology.14.1014a_references_DOI_4emyFr47WmSdZ8mM8ot0mv0lFQc"}]}