{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699995262348928.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/anie.201307484"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.201307484"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201307484"}}],"dc:title":[{"@value":"Direct Catalytic Trifluoromethylthiolation of Boronic Acids and Alkynes Employing Electrophilic Shelf‐Stable <i>N</i>‐(trifluoromethylthio)phthalimide"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>A new and safe method for the synthesis of <jats:italic>N</jats:italic>‐(trifluoromethylthio)phthalimide, a convenient and shelf‐stable reagent for the direct trifluoromethylthiolation, has been developed. <jats:italic>N</jats:italic>‐(Trifluoromethylthio)phthalimide can be used as an electrophilic source of F<jats:sub>3</jats:sub>CS<jats:sup>+</jats:sup> and reacts readily with boronic acids and alkynes under copper catalysis. The utility of CF<jats:sub>3</jats:sub>S‐containing molecules as biologically active agents, the mild reaction conditions employed, and the high tolerance of functional groups demonstrate the potential of this new methodology to be widely applied in organic synthesis as well as industrial pharmaceutical and agrochemical research and development.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699995262348929","@type":"Researcher","foaf:name":[{"@value":"Roman Pluta"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995262348928","@type":"Researcher","foaf:name":[{"@value":"Pavlo Nikolaienko"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995262348930","@type":"Researcher","foaf:name":[{"@value":"Magnus Rueping"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"14337851"},{"@type":"EISSN","@value":"15213773"}],"prism:publicationName":[{"@value":"Angewandte Chemie International Edition"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2014-01-21","prism:volume":"53","prism:number":"6","prism:startingPage":"1650","prism:endingPage":"1653"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.201307484"},{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201307484"}],"createdAt":"2014-01-21","modifiedAt":"2023-10-17","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360002214631261312","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Synthesis of Aryl Triflones through the Trifluoromethanesulfonylation of Benzynes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232525559168","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Ortho-lithiation reaction of aryl triflones"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004233249877504","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Copper-Catalyzed Regioselective Trifluoromethylthiolation of Pyrroles by Trifluoromethanesulfonyl Hypervalent Iodonium Ylide"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285704871055872","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Synthesis of Billard–Langlois Reagents and their Derivatives by Copper‐Catalyzed <i>N</i>‐Trifluoromethylthiolation of Arylamines with a Trifluoromethanesulfonyl Hypervalent Iodonium Ylide"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565164361595520","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Photocatalytic Trifluoromethylthiolation of Aromatic Alkenes Associated with Hydroxylation and Alkoxylation"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204142494208","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Development of Shelf-Stable Reagents for Fluoro-Functionalization Reactions"},{"@value":"Award Accounts : The Chemical Society of Japan Award for Creative Work for 2014 : Development of Shelf-Stable Reagents for Fluoro-Functionalization Reactions"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/anie.201307484"},{"@type":"CROSSREF","@value":"10.1002/open.201700204_references_DOI_QntrWnZAFQEs295piQ27Fi0tOww"},{"@type":"CROSSREF","@value":"10.1021/ol503616y_references_DOI_QntrWnZAFQEs295piQ27Fi0tOww"},{"@type":"CROSSREF","@value":"10.1002/ajoc.201500067_references_DOI_QntrWnZAFQEs295piQ27Fi0tOww"},{"@type":"CROSSREF","@value":"10.1002/ajoc.201600562_references_DOI_QntrWnZAFQEs295piQ27Fi0tOww"},{"@type":"CROSSREF","@value":"10.1246/bcsj.20160223_references_DOI_QntrWnZAFQEs295piQ27Fi0tOww"},{"@type":"CROSSREF","@value":"10.1016/j.tet.2018.07.055_references_DOI_QntrWnZAFQEs295piQ27Fi0tOww"}]}