{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699995537537664.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.tetlet.2007.07.179"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0040403907015092?httpAccept=text/xml"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0040403907015092?httpAccept=text/plain"}}],"dc:title":[{"@value":"Construction of the taxane skeleton via the stereoselective conjugate addition of cyanide and the intramolecular B-alkyl Suzuki–Miyaura coupling reaction"}],"description":[{"notation":[{"@value":"Abstract   Construction of the taxane skeleton via the stereoselective conjugate addition of cyanide and the intramolecular B-alkyl Suzuki–Miyaura coupling reaction is described. A conjugate addition of cyanide to enone 17 proceeded diastereoselectively to provide the desired 18 incorporating the correct C3 stereogenic center in the taxol C-ring. The intramolecular B-alkyl Suzuki–Miyaura coupling reaction of 22, which was derived from 18, successfully furnished the taxol B-ring in 81% yield."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699995537537664","@type":"Researcher","foaf:name":[{"@value":"Masayuki Utsugi"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995537537792","@type":"Researcher","foaf:name":[{"@value":"Yasuaki Kamada"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995537537794","@type":"Researcher","foaf:name":[{"@value":"Hidetoshi Miyamoto"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995537537793","@type":"Researcher","foaf:name":[{"@value":"Masahisa Nakada"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00404039"}],"prism:publicationName":[{"@value":"Tetrahedron Letters"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2007-09","prism:volume":"48","prism:number":"39","prism:startingPage":"6868","prism:endingPage":"6872"},"reviewed":"false","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S0040403907015092?httpAccept=text/xml"},{"@id":"https://api.elsevier.com/content/article/PII:S0040403907015092?httpAccept=text/plain"}],"createdAt":"2007-08-01","modifiedAt":"2019-01-05","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360848657457354752","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Synthesis of medium-sized carbocyclic ketones via the intramolecular B-alkyl Liebeskind–Srogl coupling reaction"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848657457538432","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A short and enantioselective preparation of taxol A-ring fragment"}]},{"@id":"https://cir.nii.ac.jp/crid/1882553967627086208","@type":"Dataset","relationType":["isSupplementedBy"],"jpcoar:relatedTitle":[{"@value":"CCDC 653251: Experimental Crystal Structure Determination"}]},{"@id":"https://cir.nii.ac.jp/crid/2050025942155224064","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Research on the efficient enantioselective total synthesis of useful bioactive polycyclic compounds"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2007.07.179"},{"@type":"OPENAIRE","@value":"doi_dedup___::cb81cdb0aff5070e5aff930e7ec0833e"},{"@type":"CROSSREF","@value":"10.1246/bcsj.20210329_references_DOI_KU21MZCwayFU4VpOsJ1joLW7skA"},{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2013.01.115_references_DOI_KU21MZCwayFU4VpOsJ1joLW7skA"},{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2011.10.148_references_DOI_KU21MZCwayFU4VpOsJ1joLW7skA"}]}