{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699995589394432.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2166/wst.1992.0286"}},{"identifier":{"@type":"URI","@value":"http://iwaponline.com/wst/article-pdf/25/11/149/102606/149.pdf"}}],"dc:title":[{"@value":"Water Pollution by Cadmium and the Onset of Itai-itai Disease"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Cadmium (Cd) from a zinc mine polluted Jinzu River basin, Toyama prefecture and produced a disease with severe bone pain (Itai-itai disease), from the early part of the 20th century. Cd caused renal tubular dysfunction and osteomalacia accompanied by osteoporosis. The main symptoms of the disease were bone pain, pseud fracture (Looser's zone), fracture, and renal tubular dysfunction. The pollution of paddy-field soil by Cd still remains and our epidemio1ogica1 studies of the inhabitants living in the Cd-polluted areas show the presence of renal tubular dysfunction and decrease of bone mass; characteristic of Itai-itai disease.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380848482807192587","@type":"Researcher","foaf:name":[{"@value":"M. Kasuya"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995589394433","@type":"Researcher","foaf:name":[{"@value":"H. Teranishi"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995589394436","@type":"Researcher","foaf:name":[{"@value":"K. Aoshima"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995589394438","@type":"Researcher","foaf:name":[{"@value":"T. Katoh"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995589394437","@type":"Researcher","foaf:name":[{"@value":"H. Horiguchi"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995589394435","@type":"Researcher","foaf:name":[{"@value":"Y. Morikawa"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995589394432","@type":"Researcher","foaf:name":[{"@value":"M. Nishijo"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995589394439","@type":"Researcher","foaf:name":[{"@value":"K. Iwata"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"02731223"},{"@type":"EISSN","@value":"19969732"}],"prism:publicationName":[{"@value":"Water Science and Technology"}],"dc:publisher":[{"@value":"IWA Publishing"}],"prism:publicationDate":"1992-06-01","prism:volume":"25","prism:number":"11","prism:startingPage":"149","prism:endingPage":"156"},"reviewed":"false","url":[{"@id":"http://iwaponline.com/wst/article-pdf/25/11/149/102606/149.pdf"}],"createdAt":"2018-05-18","modifiedAt":"2020-03-28","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360847872202050304","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Hospital-based screening to detect patients with cadmium nephropathy in cadmium-polluted areas in Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206361998080","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Current Status of Cadmium Exposure among Japanese, Especially Regarding the Safety Standard for Cadmium Concentration in Rice and Adverse Effects on Proximal Renal Tubular Function Observed in Farmers Exposed to Cadmium through Consumption of Self-Grown Rice"},{"@language":"ja","@value":"日本人のカドミウム曝露の現状"},{"@value":"日本人のカドミウム曝露の現状 : 特に米中カドミウム濃度の基準値及び農家の自家産米摂取による曝露とその近位尿細管機能への影響"},{"@language":"ja-Kana","@value":"ニホンジン ノ カドミウム バクロ ノ ゲンジョウ : トクニ ベイチュウ カドミウム ノウド ノ キジュンチ オヨビ ノウカ ノ ジカ サンマイ セッシュ ニ ヨル バクロ ト ソノ キン イ ニョウ サイカン キノウ エ ノ エイキョウ"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.2166/wst.1992.0286"},{"@type":"CROSSREF","@value":"10.1265/jjh.67.447_references_DOI_6Ygl7koFLFhKL4kMyhWDzLBdqCJ"},{"@type":"CROSSREF","@value":"10.1186/s12199-019-0762-3_references_DOI_6Ygl7koFLFhKL4kMyhWDzLBdqCJ"}]}