Bimodal rheotactic behavior reflects flagellar beat asymmetry in human sperm cells
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- Anton Bukatin
- St. Petersburg Academic University, St. Petersburg 194021, Russia;
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- Igor Kukhtevich
- Institute for Analytical Instrumentation of the Russian Academy of Sciences, St. Petersburg 198095, Russia;
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- Norbert Stoop
- Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139-4307;
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- Jörn Dunkel
- Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139-4307;
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- Vasily Kantsler
- Department of Physics, University of Warwick, Coventry CV4 7AL, United Kingdom
書誌事項
- 公開日
- 2015-12-10
- 権利情報
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- http://www.pnas.org/preview_site/misc/userlicense.xhtml
- DOI
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- 10.1073/pnas.1515159112
- 公開者
- Proceedings of the National Academy of Sciences
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説明
<jats:title>Significance</jats:title> <jats:p>Successful sperm navigation is essential for sexual reproduction, yet we still understand relatively little about how sperm cells are able to adapt their swimming motion in response to chemical and physical cues. This lack of knowledge is owed to the fact that it has been difficult to observe directly the full 3D dynamics of the whip-like flagellum that propels the cell through the fluid. To overcome this deficiency, we apply a new algorithm to reconstruct the 3D beat patterns of human sperm cells in experiments under varying flow conditions. Our analysis reveals that the swimming strokes of human sperm are considerably more complex than previously thought, and that sperm may use their heads as rudders to turn right or left.</jats:p>
収録刊行物
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- Proceedings of the National Academy of Sciences
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Proceedings of the National Academy of Sciences 112 (52), 15904-15909, 2015-12-10
Proceedings of the National Academy of Sciences
