{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699995883883776.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1021/la0524925"}},{"identifier":{"@type":"URI","@value":"https://pubs.acs.org/doi/pdf/10.1021/la0524925"}},{"identifier":{"@type":"PMID","@value":"16430282"}}],"dc:title":[{"@value":"Mode of Interaction of Amphiphilic α-Helical Peptide with Phosphatidylcholines at the Air−Water Interface"}],"description":[{"notation":[{"@value":"Surface pressure (pi)-, surface potential (deltaV)-, and dipole moment (mu(perpendicular))-area (A) isotherms and morphological behavior were examined for monolayers of a newly designed 18-mer amphiphilic alpha-helical peptide (Hel 13-5), DPPC, and DPPC/egg-PC (1:1) and their combinations by the Wilhelmy method, ionizing electrode method, fluorescence microscopy (FM), and atomic force microscopy (AFM). The newly designed Hel 13-5 showed rapid adsorption into the air-liquid interface to form interfacial films such as a SP-B function. Regardless of the composition and constituents in their multicomponent system of DPPC/egg-PC, the collapse pressure (pi(c); approximately 42 mN m(-1)) was constant, implying that Hel 13-5 with the fluid composition of egg-PC is squeezed out of Hel 13-5/DPPC/egg-PC monolayers accompanying a two- to three-dimensional phase transformation. FM showed that adding a small amount of Hel 13-5 to DPPC induced a dispersed pattern of ordered domains with a \"moth-eaten\" appearance, whereas shrinkage of ordered domains in size occurred for the DPPC/egg-PC mixture with Hel 13-5. Furthermore, AFM indicated that (i) the intermediate phase was formed in pure Hel 13-5 systems between monolayer states and excluded nanoparticles, (ii) protrusions necessarily located on DPPC monolayers, and (iii) beyond the collapse pressure of Hel 13-5, Hel 13-5 was squeezed out of the system into the aqueous subphase. Furthermore, hysteresis curves of these systems nicely resemble those of the DPPC/SP-B and DPPC/SP-C mixtures reported before."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381699995883883779","@type":"Researcher","foaf:name":[{"@value":"Hiromichi Nakahara"}],"jpcoar:affiliationName":[{"@value":"Division of Biointerfacial Science, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, 6-1-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan; and Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995883883781","@type":"Researcher","foaf:name":[{"@value":"Shohei Nakamura"}],"jpcoar:affiliationName":[{"@value":"Division of Biointerfacial Science, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, 6-1-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan; and Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995883883780","@type":"Researcher","foaf:name":[{"@value":"Takato Hiranita"}],"jpcoar:affiliationName":[{"@value":"Division of Biointerfacial Science, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, 6-1-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan; and Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995883883778","@type":"Researcher","foaf:name":[{"@value":"Hideya Kawasaki"}],"jpcoar:affiliationName":[{"@value":"Division of Biointerfacial Science, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, 6-1-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan; and Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995883883782","@type":"Researcher","foaf:name":[{"@value":"Sannamu Lee"}],"jpcoar:affiliationName":[{"@value":"Division of Biointerfacial Science, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, 6-1-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan; and Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995883883776","@type":"Researcher","foaf:name":[{"@value":"Gohsuke Sugihara"}],"jpcoar:affiliationName":[{"@value":"Division of Biointerfacial Science, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, 6-1-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan; and Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699995883883777","@type":"Researcher","foaf:name":[{"@value":"Osamu Shibata"}],"jpcoar:affiliationName":[{"@value":"Division of Biointerfacial Science, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan; Department of Chemistry, Graduate School of Science, Kyushu University, 6-1-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan; and Department of Chemistry, Faculty of Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"07437463"},{"@type":"EISSN","@value":"15205827"}],"prism:publicationName":[{"@value":"Langmuir"}],"dc:publisher":[{"@value":"American Chemical Society (ACS)"}],"prism:publicationDate":"2005-12-24","prism:volume":"22","prism:number":"3","prism:startingPage":"1182","prism:endingPage":"1192"},"reviewed":"false","url":[{"@id":"https://pubs.acs.org/doi/pdf/10.1021/la0524925"}],"createdAt":"2006-01-24","modifiedAt":"2023-05-06","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Air","dc:title":"Air"},{"@id":"https://cir.nii.ac.jp/all?q=Molecular%20Sequence%20Data","dc:title":"Molecular Sequence Data"},{"@id":"https://cir.nii.ac.jp/all?q=Water","dc:title":"Water"},{"@id":"https://cir.nii.ac.jp/all?q=Microscopy,%20Atomic%20Force","dc:title":"Microscopy, Atomic Force"},{"@id":"https://cir.nii.ac.jp/all?q=Microscopy,%20Fluorescence","dc:title":"Microscopy, Fluorescence"},{"@id":"https://cir.nii.ac.jp/all?q=Phosphatidylcholines","dc:title":"Phosphatidylcholines"},{"@id":"https://cir.nii.ac.jp/all?q=Adsorption","dc:title":"Adsorption"},{"@id":"https://cir.nii.ac.jp/all?q=Amino%20Acid%20Sequence","dc:title":"Amino Acid Sequence"},{"@id":"https://cir.nii.ac.jp/all?q=Peptides","dc:title":"Peptides"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004233563882368","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The role of palmitic acid in pulmonary surfactant systems by Langmuir monolayer study: Lipid–peptide interactions"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142697210368","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Investigation on the Interactions between Self-Assembled 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