{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699996288445952.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.mrfmmm.2004.10.010"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0027510704004816?httpAccept=text/xml"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0027510704004816?httpAccept=text/plain"}},{"identifier":{"@type":"PMID","@value":"15748636"}}],"dc:title":[{"@value":"UVR-induced G–C to C–G transversions from oxidative DNA damage"}],"description":[{"notation":[{"@value":"Many oxidizing agents induce G-C to T-A and G-C to C-G transversions, and the frequency largely depends on the oxidative conditions. Guanine is the most oxidizable base among natural bases. The typical oxidative lesion product 8-oxoguanine (8-oxoG) is responsible for G-C to T-A transversion but not for G-C to C-G transversion, and 8-oxoG is more readily oxidized than guanine because of its lowered ionization potential. Recently, imidazolone (Iz), guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) have been demonstrated as oxidative lesion products of guanine and 8-oxoG, which could be responsible for G-C to C-G transversions by forming specific base pair formations."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420001326234863232","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70360534"},{"@type":"NRID","@value":"1000070360534"},{"@type":"NRID","@value":"9000006640082"},{"@type":"NRID","@value":"9000364822371"},{"@type":"NRID","@value":"9000257967128"},{"@type":"NRID","@value":"9000318156986"},{"@type":"NRID","@value":"9000398143772"},{"@type":"NRID","@value":"9000272989340"},{"@type":"NRID","@value":"9000397801721"},{"@type":"NRID","@value":"9000006373636"},{"@type":"NRID","@value":"9000364822409"},{"@type":"NRID","@value":"9000356511503"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0054010"}],"foaf:name":[{"@value":"Katsuhito Kino"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699996288445953","@type":"Researcher","foaf:name":[{"@value":"Hiroshi Sugiyama"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"13861964"},{"@type":"PISSN","@value":"00275107"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/00275107"}],"prism:publicationName":[{"@value":"Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2005-04","prism:volume":"571","prism:number":"1-2","prism:startingPage":"33","prism:endingPage":"42"},"reviewed":"false","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/","https://www.elsevier.com/legal/tdmrep-license","https://doi.org/10.15223/policy-017","https://doi.org/10.15223/policy-037","https://doi.org/10.15223/policy-012","https://doi.org/10.15223/policy-029","https://doi.org/10.15223/policy-004"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S0027510704004816?httpAccept=text/xml"},{"@id":"https://api.elsevier.com/content/article/PII:S0027510704004816?httpAccept=text/plain"}],"createdAt":"2005-01-27","modifiedAt":"2025-12-02","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Oxidative%20Stress","dc:title":"Oxidative Stress"},{"@id":"https://cir.nii.ac.jp/all?q=Ultraviolet%20Rays","dc:title":"Ultraviolet Rays"},{"@id":"https://cir.nii.ac.jp/all?q=Hydantoins","dc:title":"Hydantoins"},{"@id":"https://cir.nii.ac.jp/all?q=Imidazoles","dc:title":"Imidazoles"},{"@id":"https://cir.nii.ac.jp/all?q=Animals","dc:title":"Animals"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=DNA%20Damage","dc:title":"DNA Damage"},{"@id":"https://cir.nii.ac.jp/all?q=Mutagens","dc:title":"Mutagens"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360021390560563456","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Genome-wide direct quantification of <i>in vivo</i> mutagenesis using high-accuracy paired-end and complementary consensus sequencing"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285714195609856","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Genotoxicity of multi-walled carbon nanotubes in 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