{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361699996405945216.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/chem.201405672"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchem.201405672"}},{"identifier":{"@type":"URI","@value":"https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201405672"}}],"dc:title":[{"@value":"Copper‐Catalyzed Difunctionalization of Activated Alkynes by Radical Oxidation–Tandem Cyclization/Dearomatization to Synthesize 3‐Trifluoromethyl Spiro[4.5]trienones"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>A copper‐catalyzed difunctionalizing trifluoromethylation of activated alkynes with the cheap reagent sodium trifluoromethanesulfinate (NaSO<jats:sub>2</jats:sub>CF<jats:sub>3</jats:sub> or Langlois’ reagent) has been developed incorporating a tandem cyclization/dearomatization process. This strategy affords a straightforward route to synthesis of 3‐(trifluoromethyl)‐spiro[4.5]trienones, and presents an example of difunctionalization of alkynes for simultaneous formation of two carbon–carbon single bonds and one carbon–oxygen double bond.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380861295159221124","@type":"Researcher","foaf:name":[{"@value":"Hui‐Liang Hua"}]},{"@id":"https://cir.nii.ac.jp/crid/1380861295159221125","@type":"Researcher","foaf:name":[{"@value":"Yu‐Tao He"}]},{"@id":"https://cir.nii.ac.jp/crid/1380861295159221127","@type":"Researcher","foaf:name":[{"@value":"Yi‐Feng Qiu"}]},{"@id":"https://cir.nii.ac.jp/crid/1380861295159221122","@type":"Researcher","foaf:name":[{"@value":"Ying‐Xiu Li"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699996405945218","@type":"Researcher","foaf:name":[{"@value":"Bo Song"}]},{"@id":"https://cir.nii.ac.jp/crid/1381699996405945221","@type":"Researcher","foaf:name":[{"@value":"Pin Gao"}]},{"@id":"https://cir.nii.ac.jp/crid/1380861295159221120","@type":"Researcher","foaf:name":[{"@value":"Xian‐Rong Song"}]},{"@id":"https://cir.nii.ac.jp/crid/1380861295159221126","@type":"Researcher","foaf:name":[{"@value":"Dong‐Hui Guo"}]},{"@id":"https://cir.nii.ac.jp/crid/1380861295159221121","@type":"Researcher","foaf:name":[{"@value":"Xue‐Yuan Liu"}]},{"@id":"https://cir.nii.ac.jp/crid/1380861295159221123","@type":"Researcher","foaf:name":[{"@value":"Yong‐Min Liang"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"09476539"},{"@type":"EISSN","@value":"15213765"}],"prism:publicationName":[{"@value":"Chemistry – A European Journal"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2014-11-28","prism:volume":"21","prism:number":"4","prism:startingPage":"1468","prism:endingPage":"1473"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchem.201405672"},{"@id":"https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201405672"}],"createdAt":"2014-11-28","modifiedAt":"2025-10-12","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360565164378487680","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Photoredox‐Catalyzed Stereoselective Conversion of Alkynes into Tetrasubstituted Trifluoromethylated Alkenes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846641825849216","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Efficient generation of perfluoroalkyl radicals from sodium perfluoroalkanesulfinates and a hypervalent iodine(<scp>iii</scp>) reagent: mild, metal-free synthesis of perfluoroalkylated organic molecules"}]},{"@id":"https://cir.nii.ac.jp/crid/2050588892096788096","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Fluoroalkylation methods for synthesizing versatile building blocks"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/chem.201405672"},{"@type":"CROSSREF","@value":"10.1246/bcsj.20190080_references_DOI_FTUHhqvIv2dwQYsqlIRgsjDjlkC"},{"@type":"CROSSREF","@value":"10.1002/anie.201505550_references_DOI_FTUHhqvIv2dwQYsqlIRgsjDjlkC"},{"@type":"CROSSREF","@value":"10.1039/c6ob01245k_references_DOI_FTUHhqvIv2dwQYsqlIRgsjDjlkC"}]}