{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361975844404137600.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1093/jmicro/dfz117"}},{"identifier":{"@type":"URI","@value":"http://academic.oup.com/jmicro/article-pdf/69/1/53/32921579/dfz117.pdf"}},{"identifier":{"@type":"PMID","@value":"32047915"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2021123465"}}],"resourceType":"学術雑誌論文(journal article)","dc:title":[{"@value":"Cellular network across cementum and periodontal ligament elucidated by FIB/SEM tomography"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title>\n               <jats:p>Cementocytes in cementum form a lacuna-canalicular network. However, the 3D ultrastructure and range of the cementocyte network are unclear. Here, the 3D ultrastructure of the cementocyte network at the interface between cementum and periodontal ligament (PDL) was investigated on the mesoscale using FIB/SEM tomography. The results revealed a cellular network of cementocytes and PDL cells. A previous histomorphological study revealed the osteocyte-osteoblast-PDL cellular network. We extended this knowledge and revealed the cementum-PDL-bone cellular network, which may orchestrate the remodeling and modification of periodontal tissue, using a suitable method for imaging of complex tissue.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1420564276177663232","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"70647784"},{"@type":"NRID","@value":"1000070647784"},{"@type":"NRID","@value":"9000412603881"},{"@type":"NRID","@value":"9000243857552"},{"@type":"NRID","@value":"9000389440715"},{"@type":"NRID","@value":"9000283225623"},{"@type":"NRID","@value":"9000379072786"},{"@type":"NRID","@value":"9000396148997"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/histo_hirashima"}],"foaf:name":[{"@value":"Shingo Hirashima"}],"jpcoar:affiliationName":[{"@value":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"},{"@value":"Dental and Oral Medical Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381975844404137481","@type":"Researcher","foaf:name":[{"@value":"Keisuke Ohta"}],"jpcoar:affiliationName":[{"@value":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"},{"@value":"Advanced Imaging Research Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1420564276186345856","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"50529518"},{"@type":"NRID","@value":"1000050529518"},{"@type":"NRID","@value":"9000243857166"},{"@type":"NRID","@value":"9000389438272"},{"@type":"NRID","@value":"9000272996850"},{"@type":"NRID","@value":"9000010725134"},{"@type":"NRID","@value":"9000257876090"},{"@type":"NRID","@value":"9000272996868"},{"@type":"NRID","@value":"9000272996872"},{"@type":"NRID","@value":"9000362186332"},{"@type":"NRID","@value":"9000398251039"},{"@type":"NRID","@value":"9000392356387"},{"@type":"NRID","@value":"9000404105360"},{"@type":"NRID","@value":"9000398148721"},{"@type":"NRID","@value":"9000018393772"}],"foaf:name":[{"@value":"Tomonoshin Kanazawa"}],"jpcoar:affiliationName":[{"@value":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381975844404137601","@type":"Researcher","foaf:name":[{"@value":"Akinobu Togo"}],"jpcoar:affiliationName":[{"@value":"Advanced Imaging Research Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381975844404137479","@type":"Researcher","foaf:name":[{"@value":"Risa Tsuneyoshi"}],"jpcoar:affiliationName":[{"@value":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381975844404137352","@type":"Researcher","foaf:name":[{"@value":"Jingo Kusukawa"}],"jpcoar:affiliationName":[{"@value":"Dental and Oral Medical Center, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1381975844404137480","@type":"Researcher","foaf:name":[{"@value":"Kei-ichiro Nakamura"}],"jpcoar:affiliationName":[{"@value":"Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"EISSN","@value":"20505701"}],"prism:publicationName":[{"@value":"Microscopy"}],"dc:publisher":[{"@value":"Oxford University Press (OUP)"}],"prism:publicationDate":"2020-02","prism:volume":"69","prism:number":"1","prism:startingPage":"53","prism:endingPage":"58"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","dc:rights":["https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model"],"url":[{"@id":"http://academic.oup.com/jmicro/article-pdf/69/1/53/32921579/dfz117.pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2021123465"}],"createdAt":"2019-12-30","modifiedAt":"2020-03-17","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Dental%20Cementum","dc:title":"Dental Cementum"},{"@id":"https://cir.nii.ac.jp/all?q=Mice,%20Inbred%20C57BL","dc:title":"Mice, Inbred C57BL"},{"@id":"https://cir.nii.ac.jp/all?q=Mice","dc:title":"Mice"},{"@id":"https://cir.nii.ac.jp/all?q=Periodontal%20Ligament","dc:title":"Periodontal Ligament"},{"@id":"https://cir.nii.ac.jp/all?q=Animals","dc:title":"Animals"},{"@id":"https://cir.nii.ac.jp/all?q=Tomography,%20X-Ray%20Computed","dc:title":"Tomography, X-Ray Computed"},{"@id":"https://cir.nii.ac.jp/all?q=Cells,%20Cultured","dc:title":"Cells, Cultured"}],"project":[{"@id":"https://cir.nii.ac.jp/crid/1040000781969632896","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"17K11038"},{"@type":"JGN","@value":"JP17K11038"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K11038/"}],"notation":[{"@language":"ja","@value":"FIB/SEMトモグラフィーを用いた、力学的負荷下の腱骨付着部超微形態定量解析"},{"@language":"en","@value":"Comparison of Structural Properties Between Postnatal and Adult Tendon Insertion with FIB/SEM Tomography in Rat"}]},{"@id":"https://cir.nii.ac.jp/crid/1040000782020777472","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"19K11733"},{"@type":"JGN","@value":"JP19K11733"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K11733/"}],"notation":[{"@language":"ja","@value":"胎児期栄養環境エピゲノム変化による生活習慣病発症機序と予防の形態・テロメア解析"},{"@language":"en","@value":"Morphological and telomere analysis of pathogenesis and prevention of lifestyle-related diseases due to fetal nutritional environment epigenomic changes"}]},{"@id":"https://cir.nii.ac.jp/crid/1040282256950362368","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"17K17090"},{"@type":"JGN","@value":"JP17K17090"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17K17090/"}],"notation":[{"@language":"ja","@value":"新機軸イメージングによる歯根膜線維形成過程の解明"},{"@language":"en","@value":"An investigation into the formation processes of collagen bundles in periodontal ligament by innovative imaging methods"}]},{"@id":"https://cir.nii.ac.jp/crid/1040848250649400576","@type":"Project","projectIdentifier":[{"@type":"KAKEN","@value":"20H03290"},{"@type":"JGN","@value":"JP20H03290"},{"@type":"URI","@value":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20H03290/"}],"notation":[{"@language":"ja","@value":"生体臓器・器官の結合組織内に分布する間質細胞の存在様式と動態の微細構造解析"},{"@language":"en","@value":"Three dimensional ultrastructural analyses of the distribution pattern and dynamics of the interstitial cells in the connective tissues in the mammalian body."}]}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050011307246246656","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"High-resolution image-based simulation reveals membrane strain concentration on osteocyte processes caused by tethering elements"},{"@value":"Image-based simulation reveals membrane strain concentration on osteocyte processes caused by tethering elements"}]},{"@id":"https://cir.nii.ac.jp/crid/1360002217582168576","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Three-dimensional volume imaging with electron microscopy toward connectome"}]},{"@id":"https://cir.nii.ac.jp/crid/1360011144338529024","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The Cementocyte—An Osteocyte Relative?"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285708516582144","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Three-dimensional ultrastructural analysis of cells in the periodontal ligament using focused ion beam/scanning electron microscope tomography"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619293406848","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The amazing osteocyte"}]},{"@id":"https://cir.nii.ac.jp/crid/1360292619434480256","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The interstitial cells in the colon of the rabbit"}]},{"@id":"https://cir.nii.ac.jp/crid/1360294643837859328","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"3D mesoscopic architecture of a heterogeneous cellular network in the cementum–periodontal ligament–alveolar bone complex"}]},{"@id":"https://cir.nii.ac.jp/crid/1360302866856104064","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Cementocyte-derived extracellular vesicles regulate osteoclastogenesis and osteoblastogenesis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565166030923904","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Beam deceleration for block-face scanning electron microscopy of embedded biological tissue"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567183485171072","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Anchoring structure of the calvarial periosteum revealed by focused ion beam/scanning electron microscope tomography"}]},{"@id":"https://cir.nii.ac.jp/crid/1360574095050930944","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The periodontal ligament: a unique, multifunctional connective tissue"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569469046528","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy"}]},{"@id":"https://cir.nii.ac.jp/crid/1360855569998530816","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Brain tumour cells interconnect to a functional and resistant network"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857623670647040","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Correlative volume-imaging using combined array tomography and FIB-SEM tomography with beam deceleration for 3D architecture visualization in tissue"}]},{"@id":"https://cir.nii.ac.jp/crid/1361131418281435520","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Three-dimensional ultrastructural and histomorphological analysis of the periodontal ligament with occlusal hypofunction via focused ion beam/scanning electron microscope tomography"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137043741582976","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Confocal laser scanning microscopy of human cementocytes: Analysis of three-dimensional image reconstruction"}]},{"@id":"https://cir.nii.ac.jp/crid/1361137043862184064","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Confocal microscopy of cementocytes and their lacunae and canaliculi in rat molars"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469603978240","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"3D‐electron microscopic characterization of interstitial cells in the human bladder upper lamina propria"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469857995392","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Role of periodontal ligament fibroblasts in osteoclastogenesis: a review"}]},{"@id":"https://cir.nii.ac.jp/crid/1362262945793436928","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Tooth–PDL–bone complex: Response to compressive loads encountered during mastication – A review"}]},{"@id":"https://cir.nii.ac.jp/crid/1362544420316601728","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Regulatory mechanisms of periodontal regeneration"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369514081280","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mechanobiology of tooth movement"}]},{"@id":"https://cir.nii.ac.jp/crid/1363107369515474304","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Development and general structure of the periodontium"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233268688266624","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart*"}]},{"@id":"https://cir.nii.ac.jp/crid/1364233270296017536","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Serial Section Scanning Electron Microscopy of Adult Brain Tissue Using Focused Ion Beam Milling"}]},{"@id":"https://cir.nii.ac.jp/crid/1371975844404137351","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Three-dimensional ultrastructural imaging and quantitative analysis of the periodontal ligament"}]},{"@id":"https://cir.nii.ac.jp/crid/1371975844404137472","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"The network structure of corneal fibroblasts in the rat as revealed by scanning electron microscopy"}]},{"@id":"https://cir.nii.ac.jp/crid/1371975844404137474","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Ultrastructural study of the cellular cementum in rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1371975844404137602","@type":"Product","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Three-dimensional ultrastructural analysis and histomorphometry of collagen bundles in the periodontal ligament using focused ion beam/scanning electron microscope tomography"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1093/jmicro/dfz117"},{"@type":"KAKEN","@value":"PRODUCT-23551578"},{"@type":"KAKEN","@value":"PRODUCT-23094747"},{"@type":"KAKEN","@value":"PRODUCT-23300694"},{"@type":"KAKEN","@value":"PRODUCT-22648870"},{"@type":"OPENAIRE","@value":"doi_dedup___::2ce4bcda39c85f4600cefed12cf02b6b"},{"@type":"CROSSREF","@value":"10.1093/jmicro/dfab051_references_DOI_UYsfa5tGcdQQnRtpjngCP7rCX70"},{"@type":"CROSSREF","@value":"10.1016/j.jds.2024.02.025_references_DOI_UYsfa5tGcdQQnRtpjngCP7rCX70"},{"@type":"CROSSREF","@value":"10.1007/s10237-021-01511-y_references_DOI_UYsfa5tGcdQQnRtpjngCP7rCX70"},{"@type":"CROSSREF","@value":"10.1093/jmicro/dfac015_references_DOI_UYsfa5tGcdQQnRtpjngCP7rCX70"}]}