{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361981470175844736.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1161/hypertensionaha.111.179382"}},{"identifier":{"@type":"URI","@value":"https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.111.179382"}}],"dc:title":[{"@value":"Fish, n-3 Fatty Acids, and Cardiovascular Diseases in Women of Reproductive Age"}],"dcterms:alternative":[{"@value":"A Prospective Study in a Large National Cohort"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Previous studies have indicated a protective effect of long-chain n-3 polyunsaturated fatty acids (LCn3FAs) against cardiovascular disease; however, women are underrepresented in cardiovascular research. The aim of this study was to explore the association between intake of LCn3FAs and the risk of cardiovascular disease in a large prospective cohort of young women (mean age at baseline: 29.9 years [range: 15.7–46.9]). Exposure information on 48 627 women from the Danish National Birth Cohort was linked to the Danish National Patients Registry for information on events of hypertensive, cerebrovascular, and ischemic heart disease used to define a combined measure of cardiovascular diseases. Intake of fish and LCn3FAs was assessed by a food-frequency questionnaire and telephone interviews. During follow-up (1996–2008; median: 8 years), 577 events of cardiovascular disease were identified. Low LCn3FA intake was associated with an increased risk of cardiovascular disease (adjusted hazard ratio for women in lowest versus highest LCn3FA intake group: 1.91 [95% CI: 1.26–2.90]). Restricting the sample to women who had consistently reported similar frequencies of fish intake across 3 different dietary assessment occasions tended to strengthen the relationship (hazard ratio for lowest versus highest intake: 2.91 [95% CI: 1.45–5.85]). Furthermore, the observed associations were consistent in supplementary analyses where LCn3FA intake was averaged across the 3 dietary assessment occasions, and the associations were persistent for all 3 of the individual outcomes. Our findings based on a large prospective cohort of relatively young and initially healthy women indicated that little or no intake of fish and LCn3FAs was associated with an increased risk of cardiovascular disease.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1381981470175844610","@type":"Researcher","foaf:name":[{"@value":"Marin Strøm"}],"jpcoar:affiliationName":[{"@value":"From the Maternal Nutrition Group (M.S., T.I.H., S.F.O.), Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Food Science and Nutrition (T.I.H.), School of Health Sciences, University of Iceland, Læknagardur, Reykjavik, Iceland; Department of Environmental Health (E.L.M.), Institute of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology (C.T.-P.), Copenhagen University Hospital Gentofte,..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381981470175844609","@type":"Researcher","foaf:name":[{"@value":"Thorhallur I. Halldorsson"}],"jpcoar:affiliationName":[{"@value":"From the Maternal Nutrition Group (M.S., T.I.H., S.F.O.), Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Food Science and Nutrition (T.I.H.), School of Health Sciences, University of Iceland, Læknagardur, Reykjavik, Iceland; Department of Environmental Health (E.L.M.), Institute of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology (C.T.-P.), Copenhagen University Hospital Gentofte,..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381981470175844608","@type":"Researcher","foaf:name":[{"@value":"Erik L. Mortensen"}],"jpcoar:affiliationName":[{"@value":"From the Maternal Nutrition Group (M.S., T.I.H., S.F.O.), Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Food Science and Nutrition (T.I.H.), School of Health Sciences, University of Iceland, Læknagardur, Reykjavik, Iceland; Department of Environmental Health (E.L.M.), Institute of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology (C.T.-P.), Copenhagen University Hospital Gentofte,..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381981470175844736","@type":"Researcher","foaf:name":[{"@value":"Christian Torp-Pedersen"}],"jpcoar:affiliationName":[{"@value":"From the Maternal Nutrition Group (M.S., T.I.H., S.F.O.), Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Food Science and Nutrition (T.I.H.), School of Health Sciences, University of Iceland, Læknagardur, Reykjavik, Iceland; Department of Environmental Health (E.L.M.), Institute of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology (C.T.-P.), Copenhagen University Hospital Gentofte,..."}]},{"@id":"https://cir.nii.ac.jp/crid/1381981470175844737","@type":"Researcher","foaf:name":[{"@value":"Sjurdur F. Olsen"}],"jpcoar:affiliationName":[{"@value":"From the Maternal Nutrition Group (M.S., T.I.H., S.F.O.), Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark; Faculty of Food Science and Nutrition (T.I.H.), School of Health Sciences, University of Iceland, Læknagardur, Reykjavik, Iceland; Department of Environmental Health (E.L.M.), Institute of Public Health and Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology (C.T.-P.), Copenhagen University Hospital Gentofte,..."}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"0194911X"},{"@type":"EISSN","@value":"15244563"}],"prism:publicationName":[{"@value":"Hypertension"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"2012-01","prism:volume":"59","prism:number":"1","prism:startingPage":"36","prism:endingPage":"43"},"reviewed":"false","url":[{"@id":"https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.111.179382"}],"createdAt":"2011-12-06","modifiedAt":"2024-05-13","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1390001204474221440","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Ecologic Correlations of Selected Food Groups With Disease Incidence and Mortality in Switzerland"}]},{"@id":"https://cir.nii.ac.jp/crid/1390299926126103296","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"JCS 2023 Guideline on the Primary Prevention of Coronary Artery Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1390845712993521792","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017"},{"@value":"Committee for epidemiology and clinical management of atherosclerosis. Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017"},{"@value":"Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular Disease 2017"},{"@value":"Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases"},{"@value":"Committee for Epidemiology and Clinical Management of Atherosclerosis. Japan Atherosclerosis Society Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017"}]},{"@id":"https://cir.nii.ac.jp/crid/1390863329503320320","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022"},{"@value":"Japan Atherosclerosis Society(JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Disease 2022"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1161/hypertensionaha.111.179382"},{"@type":"CROSSREF","@value":"10.2188/jea.je20130029_references_DOI_AibSVZx0yBmKoVf10S1b8azNPA1"},{"@type":"CROSSREF","@value":"10.5551/jat.gl2022_references_DOI_AibSVZx0yBmKoVf10S1b8azNPA1"},{"@type":"CROSSREF","@value":"10.1253/circj.cj-23-0285_references_DOI_AibSVZx0yBmKoVf10S1b8azNPA1"},{"@type":"CROSSREF","@value":"10.5551/jat.gl2017_references_DOI_AibSVZx0yBmKoVf10S1b8azNPA1"}]}