{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1361981471474470656.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1111/j.1651-2227.1986.tb10294.x"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1651-2227.1986.tb10294.x"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1651-2227.1986.tb10294.x"}},{"identifier":{"@type":"NAID","@value":"30034296281"}}],"dc:title":[{"@value":"Thromboembolic Complications in Children with Nephrotic Syndrome"}],"dcterms:alternative":[{"@value":"Risk and Incidence"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p><jats:bold>ABSTRACT. </jats:bold> Coagulation studies were performed in 16 children with steroid responsive minimal change nephrotic syndrome in order to elucidate the incidence of thromboembolic complications. Fibrinogen and a2‐macroglobulin concentrations were inversely correlated with serum albumin concentrations, antithrombin III correlated positively (<jats:italic>p</jats:italic><0.001). Factor VIII:R:AG concentration was elevated. Coagulation disturbances in children are not less severe than in adults with nephrotic syndrome. Combined scintigraphic pulmonary ventilation and perfusion studies were employed in 26 children to detect noninvasively events of pulmonary embolism, respectively their residual changes. The lung scintigraphic investigation demonstrated a pattern consistent with pulmonary embolism in 7 patients (27.9%), residual changes in 10 (38.5%) and normal findings in 9 (34.9%). The incidence of thromboembolic complications in children with severe nephrotic syndrome is as high as reported for adults. Pulmonary symptoms may well be due to pulmonary embolism.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1583950401167577984","@type":"Researcher","foaf:name":[{"@value":"P. F. HOYER"}]},{"@id":"https://cir.nii.ac.jp/crid/1381981471474470659","@type":"Researcher","foaf:name":[{"@value":"S. GONDA"}]},{"@id":"https://cir.nii.ac.jp/crid/1381981471474470658","@type":"Researcher","foaf:name":[{"@value":"M. BARTHELS"}]},{"@id":"https://cir.nii.ac.jp/crid/1381981471474470660","@type":"Researcher","foaf:name":[{"@value":"H. P. KROHN"}]},{"@id":"https://cir.nii.ac.jp/crid/1381981471474470657","@type":"Researcher","foaf:name":[{"@value":"J. BRODEHL"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"08035253"},{"@type":"EISSN","@value":"16512227"},{"@type":"NCID","@value":"AA0050931X"}],"prism:publicationName":[{"@value":"Acta Paediatrica"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"1986-09","prism:volume":"75","prism:number":"5","prism:startingPage":"804","prism:endingPage":"810"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1651-2227.1986.tb10294.x"},{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1651-2227.1986.tb10294.x"}],"createdAt":"2008-01-21","modifiedAt":"2023-10-21","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360588381053639040","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pediatric frequent relapsing nephrotic syndrome with multiple cerebral infarctions accompanied by patent foramen ovale and cerebral venous sinus thrombosis: a case report"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204340364800","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"軽度の低アルブミン血症にも関わらず肺動脈塞栓症を合併した特発性ネフローゼ症候群の1 例"},{"@language":"en","@value":"A case of pulmonary embolism in nephrotic syndrome with mild hypoalbuminemia"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679834536448","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A coagulation and fibrinolytic study in children with nephrotic syndrome: Evaluation of hypercoagulability by measuring plasmin-.ALPHA.2 plasmin inhibitor complex and FDP D-dimer."},{"@value":"小児ネフローゼ症候群における凝固線溶系の検討　ｐｌａｓｍｉｎ‐α２　ｐｌａｓｍｉｎ　ｉｎｈｉｂｉｔｏｒ　ｃｏｍｐｌｅｘおよびＦＤＰ　Ｄ‐ｄｉｍｅｒを中心として"}]},{"@id":"https://cir.nii.ac.jp/crid/1570854174975611520","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"小児ネフローゼ症候群におけるメチルプレドニゾロン・パルス療法の凝固・線溶系への影響"},{"@language":"en","@value":"EFFECTS OF METHYLPREDONISOLONE PULSE THERAPY ON COAGULATION AND FIBRINOLYTIC SYSTEM IN CHILDREN WITH NEPHROTIC SYNDROME"}]},{"@id":"https://cir.nii.ac.jp/crid/1571135651190313856","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"An unusual case of loin pain and nephritis"}]},{"@id":"https://cir.nii.ac.jp/crid/2051433317027795072","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Clinical practice guideline for pediatric idiopathic nephrotic syndrome 2013 : general therapy"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1111/j.1651-2227.1986.tb10294.x"},{"@type":"CIA","@value":"30034296281"},{"@type":"CROSSREF","@value":"10.1007/s10157-014-1031-9_references_DOI_kZoo5Ukgmvm8Ff2223SS9sPSG9"},{"@type":"CROSSREF","@value":"10.1186/s12882-024-03579-x_references_DOI_kZoo5Ukgmvm8Ff2223SS9sPSG9"},{"@type":"CROSSREF","@value":"10.3165/jjpn.cr.2017.0114_references_DOI_kZoo5Ukgmvm8Ff2223SS9sPSG9"}]}