{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362260173466044288.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1007/s11604-017-0620-4"}},{"identifier":{"@type":"URI","@value":"http://link.springer.com/content/pdf/10.1007/s11604-017-0620-4.pdf"}},{"identifier":{"@type":"URI","@value":"http://link.springer.com/article/10.1007/s11604-017-0620-4/fulltext.html"}},{"identifier":{"@type":"PMID","@value":"28205100"}},{"identifier":{"@type":"NAID","@value":"50012515766"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2018081988"}}],"dc:title":[{"@value":"Efficacy of oral supplemental hydration for the prevention of contrast-induced nephropathy in rats"}],"description":[{"notation":[{"@value":"To compare oral rehydration solution (ORS) with saline infusion for preventing contrast-induced nephropathy (CIN) in a rat model.Adult male Sprague-Dawley rats (310-360 g) received intravenous indomethacin (10 mg/kg), NHydration with saline prevented only the contrast-induced increase in plasma creatinine, whereas ORS prevented deleterious changes in plasma creatinine, blood urea nitrogen, and creatinine clearance as well as in urinary protein, albumin, and N-acetyl-D-glucosaminidase concentrations. Histopathologic changes noted in the CIN group were diminished in both saline and ORS groups.Both intravenous saline administration and oral hydration with ORS decreased the severity of CIN. Hydration with ORS was comparable to intravenous saline infusion in preventing CIN-associated abnormalities."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1583106130622943362","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415145765"}],"foaf:name":[{"@value":"Tamaki Matsunami"}]},{"@id":"https://cir.nii.ac.jp/crid/1583106130622943361","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415145766"}],"foaf:name":[{"@value":"Kazuo Hino"}]},{"@id":"https://cir.nii.ac.jp/crid/1583106130622943360","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415145767"}],"foaf:name":[{"@value":"Rie Dosho"}]},{"@id":"https://cir.nii.ac.jp/crid/1583106130622943365","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415145768"}],"foaf:name":[{"@value":"Sho Miyatake"}]},{"@id":"https://cir.nii.ac.jp/crid/1583106130622943363","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415145769"}],"foaf:name":[{"@value":"Goro Ebisu"}]},{"@id":"https://cir.nii.ac.jp/crid/1583106130622943364","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000415145770"}],"foaf:name":[{"@value":"Ryohei Kuwatsuru"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"18671071"},{"@type":"EISSN","@value":"1867108X"}],"prism:publicationName":[{"@value":"Japanese Journal of Radiology"}],"dc:publisher":[{"@value":"Springer Science and Business Media 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