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Xia\n            <jats:italic>et al.</jats:italic>\n            investigated the reprogramming dynamics of three key histone modifications in human early embryonic development. The reprogramming in humans is highly species-specific and different than that in mice. A globally permissive chromatin state connects parental and zygotic epigenomes during maternal-to-zygotic transition. Inner-cell mass-specific, but not trophectoderm-specific, genes are asymmetrically patterned by a histone mark during early lineage segregation.\n          </jats:p>\n          <jats:p>\n            <jats:italic>Science</jats:italic>\n            , this issue p.\n            <jats:related-article xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"doi\" issue=\"6451\" page=\"353\" related-article-type=\"in-this-issue\" vol=\"365\" xlink:href=\"10.1126/science.aaw5118\">353</jats:related-article>\n          </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1382262943539785602","@type":"Researcher","foaf:name":[{"@value":"Weikun Xia"}],"jpcoar:affiliationName":[{"@value":"Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China."}]},{"@id":"https://cir.nii.ac.jp/crid/1382262943539785607","@type":"Researcher","foaf:name":[{"@value":"Jiawei Xu"}],"jpcoar:affiliationName":[{"@value":"Center for Reproductive Medicine, Henan Key Laboratory of Reproduction and Genetics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China."}]},{"@id":"https://cir.nii.ac.jp/crid/1382262943539785735","@type":"Researcher","foaf:name":[{"@value":"Guang Yu"}],"jpcoar:affiliationName":[{"@value":"Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China."}]},{"@id":"https://cir.nii.ac.jp/crid/1382262943539785604","@type":"Researcher","foaf:name":[{"@value":"Guidong Yao"}],"jpcoar:affiliationName":[{"@value":"Center for Reproductive Medicine, Henan Key Laboratory of Reproduction and Genetics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China."}]},{"@id":"https://cir.nii.ac.jp/crid/1382262943539785737","@type":"Researcher","foaf:name":[{"@value":"Kai Xu"}],"jpcoar:affiliationName":[{"@value":"Center for Stem Cell Biology and Regenerative Medicine, MOE Key Laboratory of Bioinformatics, THU-PKU Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China."}]},{"@id":"https://cir.nii.ac.jp/crid/1382262943539785610","@type":"Researcher","foaf:name":[{"@value":"Xueshan Ma"}],"jpcoar:affiliationName":[{"@value":"Center for Reproductive Medicine, Henan Key Laboratory of Reproduction and Genetics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China."}]},{"@id":"https://cir.nii.ac.jp/crid/1382262943539785732","@type":"Researcher","foaf:name":[{"@value":"Nan Zhang"}],"jpcoar:affiliationName":[{"@value":"Center for Reproductive Medicine, Henan Key Laboratory of Reproduction and Genetics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 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