{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362262945387967360.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/0006-8993(84)90811-4"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:0006899384908114?httpAccept=text/xml"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:0006899384908114?httpAccept=text/plain"}},{"identifier":{"@type":"PMID","@value":"6713171"}},{"identifier":{"@type":"NAID","@value":"30003092748"}}],"dc:title":[{"@value":"Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decar☐ylase as a marker"}],"description":[{"notation":[{"@value":"The distribution of histidine decarboxylase-like immunoreactivity (HDCI) in the rat central nervous system was studied by the indirect immunofluorescence technique. HDCI cell bodies were concentrated in the posterior hypothalamic area, such as in the tuberal magnocellular nucleus, caudal magnocellular nucleus, posterior hypothalamic nucleus and lateral hypothalamus just lateral to the fasciculus mammillothalamicus at the level of the posterior hypothalamic nucleus. Extensive networks of HDCI fibers of various densities were found in many areas of the brain; they were particularly dense in the hypothalamus but were also found in the following areas: rostrally in the cerebral cortex, olfactory nuclei, medial amygdaloid nucleus, n. tractus diagonalis, and bed nucleus of the stria terminalis, and caudally in the central gray matter of the midbrain and pons, auditory system, n. vestibularis medialis, n. originis nervi facialis, n. parabrachialis, n. commissuralis, n. tractus solitarii, and n. raphe dorsalis."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1382262945387967492","@type":"Researcher","foaf:name":[{"@value":"Takehiko Watanabe"}]},{"@id":"https://cir.nii.ac.jp/crid/1382262945387967362","@type":"Researcher","foaf:name":[{"@value":"Yoshitaka Taguchi"}]},{"@id":"https://cir.nii.ac.jp/crid/1382262945387967361","@type":"Researcher","foaf:name":[{"@value":"Sadao Shiosaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1382262945387967360","@type":"Researcher","foaf:name":[{"@value":"Junya Tanaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1382262945387967488","@type":"Researcher","foaf:name":[{"@value":"Hiroaki Kubota"}]},{"@id":"https://cir.nii.ac.jp/crid/1382262945387967490","@type":"Researcher","foaf:name":[{"@value":"Yoshitake Terano"}]},{"@id":"https://cir.nii.ac.jp/crid/1382262945387967491","@type":"Researcher","foaf:name":[{"@value":"Masaya Tohyama"}]},{"@id":"https://cir.nii.ac.jp/crid/1382262945387967489","@type":"Researcher","foaf:name":[{"@value":"Hiroshi Wada"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00068993"}],"prism:publicationName":[{"@value":"Brain Research"}],"dc:publisher":[{"@value":"Elsevier 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Strains"},{"@id":"https://cir.nii.ac.jp/all?q=Antigen-Antibody%20Complex","dc:title":"Antigen-Antibody Complex"},{"@id":"https://cir.nii.ac.jp/all?q=Histidine%20Decarboxylase","dc:title":"Histidine Decarboxylase"},{"@id":"https://cir.nii.ac.jp/all?q=Rats","dc:title":"Rats"},{"@id":"https://cir.nii.ac.jp/all?q=Animals","dc:title":"Animals"},{"@id":"https://cir.nii.ac.jp/all?q=Tissue%20Distribution","dc:title":"Tissue Distribution"},{"@id":"https://cir.nii.ac.jp/all?q=Histamine","dc:title":"Histamine"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004232397235456","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Mechanism of the histamine H3 receptor-mediated increase in exploratory locomotor activity and anxiety-like behaviours in mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004236322451840","@type":"Article","resourceType":"学術雑誌論文(journal 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pain perception: A study using receptors gene knockout mice."},{"@language":"ja","@value":"受容体・チャネル遺伝子の改変修飾と疾病・治療モデル　　４　　ノックアウトマウス研究から明らかにされる痛み受容におけるヒスタミン受容体の役割"},{"@value":"ノックアウトマウス研究から明らかにされる痛み受容におけるヒスタミン受容体の役割"},{"@language":"ja-Kana","@value":"ノックアウトマウス ケンキュウ カラ アキラカ ニ サレル イタミ ジュヨウ ニ オケル ヒスタミン ジュヨウタイ ノ ヤクワリ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679250213376","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Role of central histamine in amygdaloid kindled seizures."},{"@language":"ja","@value":"中枢ヒスタミン神経系とへん桃核キンドリング"},{"@value":"中枢ヒスタミン神経系と扁桃核キンドリング"},{"@language":"ja-Kana","@value":"チュウスウ ヒスタミン シンケイケイ ト ヘントウカク キンドリング"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679264584960","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effects of thiamine administration on hypothermia 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