{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362544418359399296.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/asia.200800411"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fasia.200800411"}},{"identifier":{"@type":"URI","@value":"https://aces.onlinelibrary.wiley.com/doi/pdf/10.1002/asia.200800411"}},{"identifier":{"@type":"PMID","@value":"19156655"}}],"dc:title":[{"@value":"Synthesis of a Sialic Acid Containing Complex‐Type <i>N</i>‐Glycan on a Solid Support"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p><jats:bold>On solid ground</jats:bold>: A new solid‐phase synthesis of <jats:italic>N</jats:italic>‐linked glycans featuring 1) highly stereoselective β‐mannosylation and microfluidic α‐sialylation and 2) efficient glycosylation of the <jats:italic>N</jats:italic>‐phenyltrifluoroacetimidate units on JandaJel resin is reported. Reagent concentration effects by a fluorous solvent are effectively applied, and the use of these methods results in the first synthesis of a sialic acid containing complex‐type <jats:italic>N</jats:italic>‐glycan on a solid support.<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http://www.w3.org/1999/xlink\" mimetype=\"image/gif\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic/mcontent.gif\"><jats:alt-text>magnified image</jats:alt-text></jats:graphic></jats:boxed-text></jats:p><jats:p>A new solid‐phase synthesis of <jats:italic>N</jats:italic>‐linked glycans featuring 1) highly stereoselective β‐mannosylation and microfluidic α‐sialylation and 2) efficient glycosylation of the <jats:italic>N</jats:italic>‐phenyltrifluoroacetimidate units on JandaJel resin is reported. Reagent concentration effects by a fluorous solvent are effectively applied, and the use of these methods results in the first synthesis of a sialic acid containing complex‐type <jats:italic>N</jats:italic>‐glycan on a solid support.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1382544418359399302","@type":"Researcher","foaf:name":[{"@value":"Katsunori Tanaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544418359399297","@type":"Researcher","foaf:name":[{"@value":"Yohei Fujii"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544418359399300","@type":"Researcher","foaf:name":[{"@value":"Hiroomi Tokimoto"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544418359399303","@type":"Researcher","foaf:name":[{"@value":"Yasutaka Mori"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579818047195520","@type":"Researcher","foaf:name":[{"@value":"Shin‐ichi Tanaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1380579818047195521","@type":"Researcher","foaf:name":[{"@value":"Guang‐ming Bao"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544418359399301","@type":"Researcher","foaf:name":[{"@value":"Eric R. O. Siwu"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544418359399296","@type":"Researcher","foaf:name":[{"@value":"Aiko Nakayabu"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544418359399304","@type":"Researcher","foaf:name":[{"@value":"Koichi Fukase"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"18614728"},{"@type":"EISSN","@value":"1861471X"}],"prism:publicationName":[{"@value":"Chemistry – An Asian 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Acid"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004233130804608","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Chemical Synthesis of a Complex-Type <i>N</i>-Glycan Containing a Core Fucose"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285704893784064","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Indirect Cation‐Flow Method: Flash Generation of Alkoxycarbenium Ions and Studies on the Stability of Glycosyl Cations"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285708539944320","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Reinvestigation of the C5-acetamide sialic acid donor for α-selective sialylation: practical procedure under microfluidic 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