{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362544420974641024.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1097/pas.0b013e318262787c"}},{"identifier":{"@type":"URI","@value":"http://journals.lww.com/00000478-201209000-00002"}},{"identifier":{"@type":"PMID","@value":"22895264"}},{"identifier":{"@type":"HANDLE","@value":"10533/134347"}}],"dc:title":[{"@value":"Intracholecystic Papillary-Tubular Neoplasms (ICPN) of the Gallbladder (Neoplastic Polyps, Adenomas, and Papillary Neoplasms That Are ≥1.0 cm)"}],"dcterms:alternative":[{"@value":"Clinicopathologic and Immunohistochemical Analysis of 123 Cases"}],"description":[{"notation":[{"@value":"The literature on the clinicopathologic characteristics of tumoral intraepithelial neoplasms (neoplastic polyps) of the gallbladder (GB) is fairly limited, due in part to the variability in definition and terminology. Most reported adenomas (pyloric gland type and others) were microscopic and thus regarded as clinically inconsequential, whereas papillary in situ carcinomas have been largely considered a type of invasive adenocarcinoma under the heading of \"papillary adenocarcinomas.\" In this study, 123 GB cases that have a well-defined exophytic preinvasive neoplasm measuring ≥1 cm were analyzed. The patients were predominantly female (F/M=2:1) with a mean age of 61 y and a median tumor size of 2.2 cm. Half of the patients presented with pain, and in the other half the neoplasm was detected incidentally. Other neoplasms, most being gastrointestinal tract malignancies, were present in 22% of cases. Gallstones were identified in only 20% of cases. Radiologically, almost half were diagnosed as \"cancer,\" roughly half with polypoid tumor, and in 10% the lesion was missed. Pathologic findings: (1) The predominant configuration was papillary in 43%, tubulopapillary in 31%, tubular in 26%. (2) Each case was assigned a final lineage type on the basis of the predominant pattern (75% of the lesion) on morphology, and supported with specific immunohistochemical cell lineage markers. The predominant cell lineage could be identified as biliary in 50% (66% of which were MUC1), gastric foveolar in 16% (all were MUC5AC), gastric pyloric in 20% (92% MUC6), intestinal in 8% (100% CK20; 75% CDX2; 50%, MUC2), and oncocytic in 6% (17% HepPar and 17% MUC6); however, 90% of cases had some amount of secondary or unclassifiable pattern and hybrid immunophenotypes. (3) Of the cases that would have qualified as \"pyloric gland adenoma,\" 21/24 (88%) had at least focal high-grade dysplasia and 18% had associated invasive carcinoma. Conversely, 8 of 47 \"papillary adenocarcinoma\"-type cases displayed some foci of low-grade dysplasia, and 15/47 (32%) had no identifiable invasion. (4) Overall, 55% of the cases had an associated invasive carcinoma (pancreatobiliary type, 58; others, 10). Factors associated significantly with invasion were the extent of high-grade dysplasia, cell type (biliary or foveolar), and papilla formation. Among systematically analyzed invasive carcinomas, tumoral intraepithelial neoplasia was detected in 6.4% (39/606). (5) The 3-year actuarial survival was 90% for cases without invasion and 60% for those associated with invasion. In contrast, those associated with invasion had a far better clinical outcome compared with pancreatobiliary-type GB carcinomas (3-yr survival, 27%), and this survival advantage persisted even with stage-matched comparison. Death occurred in long-term follow-up even in a few noninvasive cases (4/55; median 73.5 mo) emphasizing the importance of long-term follow-up. In conclusion, tumoral preinvasive neoplasms (≥1 cm) in the GB are analogous to their pancreatic and biliary counterparts (biliary intraductal papillary neoplasms, pancreatic intraductal papillary mucinous neoplasms, and intraductal tubulopapillary neoplasms). They show variable cellular lineages, a spectrum of dysplasia, and a mixture of papillary or tubular growth patterns, often with significant overlap, warranting their classification under 1 unified parallel category, intracholecystic papillary-tubular neoplasm. Intracholecystic papillary-tubular neoplasms are relatively indolent neoplasia with significantly better prognosis compared with pancreatobiliary-type GB carcinomas. In contrast, even seemingly innocuous examples such as those referred to as \"pyloric gland adenomas\" can progress to carcinoma and be associated with invasion and fatal outcome."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1382544420974641035","@type":"Researcher","foaf:name":[{"@value":"Volkan Adsay"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641036","@type":"Researcher","foaf:name":[{"@value":"Kee-Taek Jang"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641032","@type":"Researcher","foaf:name":[{"@value":"Juan Carlos Roa"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641026","@type":"Researcher","foaf:name":[{"@value":"Nevra Dursun"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641027","@type":"Researcher","foaf:name":[{"@value":"Nobuyuki Ohike"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641033","@type":"Researcher","foaf:name":[{"@value":"Pelin Bagci"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641028","@type":"Researcher","foaf:name":[{"@value":"Olca Basturk"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641024","@type":"Researcher","foaf:name":[{"@value":"Sudeshna Bandyopadhyay"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641029","@type":"Researcher","foaf:name":[{"@value":"Jeanette D. Cheng"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641025","@type":"Researcher","foaf:name":[{"@value":"Juan M. Sarmiento"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641031","@type":"Researcher","foaf:name":[{"@value":"Oscar Tapia Escalona"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641030","@type":"Researcher","foaf:name":[{"@value":"Michael Goodman"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641037","@type":"Researcher","foaf:name":[{"@value":"So Yeon Kong"}]},{"@id":"https://cir.nii.ac.jp/crid/1382544420974641034","@type":"Researcher","foaf:name":[{"@value":"Paul Terry"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"01475185"}],"prism:publicationName":[{"@value":"American Journal of Surgical Pathology"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"2012-09","prism:volume":"36","prism:number":"9","prism:startingPage":"1279","prism:endingPage":"1301"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"http://journals.lww.com/00000478-201209000-00002"}],"createdAt":"2012-08-15","modifiedAt":"2022-01-26","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Adenoma","dc:title":"Adenoma"},{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Mucins","dc:title":"Mucins"},{"@id":"https://cir.nii.ac.jp/all?q=Gallbladder","dc:title":"Gallbladder"},{"@id":"https://cir.nii.ac.jp/all?q=Adenocarcinoma","dc:title":"Adenocarcinoma"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Immunohistochemistry","dc:title":"Immunohistochemistry"},{"@id":"https://cir.nii.ac.jp/all?q=Neoplasms,%20Multiple%20Primary","dc:title":"Neoplasms, Multiple Primary"},{"@id":"https://cir.nii.ac.jp/all?q=Adenocarcinoma,%20Papillary","dc:title":"Adenocarcinoma, Papillary"},{"@id":"https://cir.nii.ac.jp/all?q=Polyps","dc:title":"Polyps"},{"@id":"https://cir.nii.ac.jp/all?q=Biomarkers,%20Tumor","dc:title":"Biomarkers, Tumor"},{"@id":"https://cir.nii.ac.jp/all?q=Disease%20Progression","dc:title":"Disease Progression"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Cell%20Lineage","dc:title":"Cell Lineage"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Gallbladder%20Neoplasms","dc:title":"Gallbladder Neoplasms"},{"@id":"https://cir.nii.ac.jp/all?q=Neoplasm%20Invasiveness","dc:title":"Neoplasm Invasiveness"},{"@id":"https://cir.nii.ac.jp/all?q=Aged","dc:title":"Aged"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050021692220395648","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Cholangiocyte organoids for disease, cancer, and regenerative medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004234912671616","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142453929856","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Intracholecystic papillary neoplasm of the gallbladder protruding into the common bile duct: A case report"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142695183744","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A case report of mucinous adenocarcinoma derived from intra-ampullary papillary-tubular neoplasm with a malignant course"}]},{"@id":"https://cir.nii.ac.jp/crid/1360009142744635264","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Intracholecystic papillary neoplasm arising in the cystic duct and extending into common bile duct: a case report"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013168834910976","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Whole‐genome copy number and immunohistochemical analyses on surgically resected intracholecystic papillary neoplasms"}]},{"@id":"https://cir.nii.ac.jp/crid/1360013168879881344","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Precursor Lesions of Gallbladder Carcinoma: Disease Concept, Pathology, and Genetics"}]},{"@id":"https://cir.nii.ac.jp/crid/1360025430185950848","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pathologic characterization of precursors and cholangiocarcinoma referring to peribiliary capillary plexus: a new pathologic approach to bile duct neoplasm"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565166749996928","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567184859452672","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Intracholecystic Papillary Neoplasms Are Distinct From Papillary Gallbladder Cancers"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576195086150272","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580232409483264","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pathologic patterns of invasive carcinoma associated with intraductal papillary neoplasms of bile duct (IPNB)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580232419344384","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pathologies of Precursor Lesions of Biliary Tract Carcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846639516408448","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Histological features of precancerous and early cancerous lesions of biliary tract carcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848659836148352","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pyloric Gland Adenoma (PGA) of the Gallbladder"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861704800093312","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The role of Kras and canonical Wnt pathways for tumorigenesis of extrahepatic biliary system"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861704800096896","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras"}]},{"@id":"https://cir.nii.ac.jp/crid/1360865816796737664","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pathological survey of precursor lesions in cholangiocarcinoma"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001288041501056","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"術前診断に造影MRIが有用であった胆囊粘液癌の1例"},{"@language":"en","@value":"A Mucinous Adenocarcinoma of the Gallbladder for Which Dynamic MRI Was Useful in Preoperative Diagnosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679348609280","@type":"Article","resourceType":"紀要論文(departmental bulletin paper)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Clinicopathological Study of Intracholecystic Papillary-Tubular Neoplasms (ICPNs) of the Gallbladder"}]},{"@id":"https://cir.nii.ac.jp/crid/1390292572069054080","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Case of Mucus-producing Intracholecystic Papillary Neoplasm Causing Acute Obstructive Cholangitis"},{"@language":"ja","@value":"粘液産生を伴い急性閉塞性胆管炎を併発した胆嚢内乳頭状腫瘍の1例"},{"@value":"粘液産生を伴い急性閉塞性胆管炎を併発した胆囊内乳頭状腫瘍の1例"},{"@language":"ja-Kana","@value":"ネンエキ サンセイ オ トモナイ キュウセイ ヘイソクセイタンカンエン オ ヘイハツ シタ タンノウ ナイ ニュウトウジョウ シュヨウ ノ 1レイ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390297659201039104","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Case of Intracholecystic Papillary Neoplasm with Early Recurrence of Liver Metastases after Curative Resection"},{"@language":"ja","@value":"根治切除後早期に肝転移再発したintracholecystic papillary neoplasmの1例"},{"@language":"ja-Kana","@value":"コンジ セツジョ ゴ ソウキ ニ カン テンイ サイハツ シタ intracholecystic papillary neoplasm ノ 1レイ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390300633896804864","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Case of Non-Invasive Intracholecystic Papillary Neoplasm Arising from the Rokitansky-Aschoff Sinus"},{"@language":"ja","@value":"Rokitansky-Aschoff洞内に限局発生したintracholecystic papillary neoplasmの1例"}]},{"@id":"https://cir.nii.ac.jp/crid/1390300679200396032","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Case of Intracholecystic Papillary Neoplasm with Latent Conventional Gallbladder Carcinoma"},{"@language":"ja","@value":"潜在性に通常型胆嚢癌を合併したintracholecystic papillary neoplasmの1例"},{"@value":"潜在性に通常型胆囊癌を合併したintracholecystic papillary neoplasmの1例"},{"@language":"ja-Kana","@value":"センザイセイ ニ ツウジョウ カタ タンノウガン オ ガッペイ シタ intracholecystic papillary neoplasm ノ 1レイ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390578393608423808","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Preoperative Diagnosis of Intracholecystic Papillary Neoplasm Based on Characteristic Preoperative Images: A Case Report"},{"@language":"ja","@value":"特徴的な画像所見を示し術前に診断しえた浸潤性胆囊内乳頭状腫瘍の1例"}]},{"@id":"https://cir.nii.ac.jp/crid/1390586136190624384","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Surgical Case of Metachronous Occurrence of Intracholecystic Papillary Neoplasm in the Remnant Cystic Duct 19 Years after Cholecystectomy"}]},{"@id":"https://cir.nii.ac.jp/crid/1390851198165975296","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Case of Intracystic Papillary Neoplasm Incidentally Diagnosed during Laparoscopic Cholecystectomy"},{"@language":"ja","@value":"腹腔鏡下胆嚢摘出術後に偶発的に診断されたIntracystic Papillary Neoplasmの１例"},{"@language":"ja-Kana","@value":"フククウキョウ カ タンノウ テキシュツ ジュツゴ ニ グウハツテキ ニ シンダン サレタ Intracystic Papillary Neoplasm ノ 1レイ"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1097/pas.0b013e318262787c"},{"@type":"OPENAIRE","@value":"doi_dedup___::fdbdac9ae5d8142a157f5cb65798a799"},{"@type":"CROSSREF","@value":"10.1097/sla.0000000000001173_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.3892/mco.2019.1919_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1186/s40792-020-01045-y_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1007/s12328-020-01311-4_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1111/pin.13177_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.3390/diagnostics12020341_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1007/s00428-024-03859-9_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.5833/jjgs.2023.0046_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.3919/jjsa.84.1918_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1038/modpathol.2015.61_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1097/pas.0000000000001237_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1158/0008-5472.can-21-2176_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.3919/jjsa.82.2275_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.3919/jjsa.84.448_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1016/j.anndiagpath.2022.152055_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.3390/cancers14215358_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.70352/scrj.cr.24-0175_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1002/jhbp.71_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1097/pas.0000000000001117_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.2974/kmj.71.147_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.5833/jjgs.2017.0054_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.5833/jjgs.2022.0038_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.18632/oncotarget.28349_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.18632/oncotarget.28380_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1002/jhbp.1308_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.1016/j.ejcb.2024.151472_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"},{"@type":"CROSSREF","@value":"10.15369/sujms.26.17_references_DOI_YsfH5wgnzuREjbblzDas2n22Bh8"}]}