{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362825893406287360.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1038/nn.3869"}},{"identifier":{"@type":"URI","@value":"http://www.nature.com/articles/nn.3869.pdf"}},{"identifier":{"@type":"URI","@value":"http://www.nature.com/articles/nn.3869"}},{"identifier":{"@type":"PMID","@value":"25413091"}}],"dc:title":[{"@value":"Encoding of fear learning and memory in distributed neuronal circuits"}],"description":[{"notation":[{"@value":"How sensory information is transformed by learning into adaptive behaviors is a fundamental question in neuroscience. Studies of auditory fear conditioning have revealed much about the formation and expression of emotional memories and have provided important insights into this question. Classical work focused on the amygdala as a central structure for fear conditioning. Recent advances, however, have identified new circuits and neural coding strategies mediating fear learning and the expression of fear behaviors. One area of research has identified key brain regions and neuronal coding mechanisms that regulate the formation, specificity and strength of fear memories. Other work has discovered critical circuits and neuronal dynamics by which fear memories are expressed through a medial prefrontal cortex pathway and coordinated activity across interconnected brain regions. Here we review these recent advances alongside prior work to provide a working model of the extended circuits and neuronal coding mechanisms mediating fear learning and memory."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1382825893406287360","@type":"Researcher","foaf:name":[{"@value":"Cyril Herry"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825893406287361","@type":"Researcher","foaf:name":[{"@value":"Joshua P Johansen"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"10976256"},{"@type":"EISSN","@value":"15461726"}],"prism:publicationName":[{"@value":"Nature Neuroscience"}],"dc:publisher":[{"@value":"Springer Science and Business Media LLC"}],"prism:publicationDate":"2014-11-21","prism:volume":"17","prism:number":"12","prism:startingPage":"1644","prism:endingPage":"1654"},"reviewed":"false","dc:rights":["http://www.springer.com/tdm"],"url":[{"@id":"http://www.nature.com/articles/nn.3869.pdf"},{"@id":"http://www.nature.com/articles/nn.3869"}],"createdAt":"2014-11-21","modifiedAt":"2023-05-19","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Neurons","dc:title":"Neurons"},{"@id":"https://cir.nii.ac.jp/all?q=Auditory%20Pathways","dc:title":"Auditory Pathways"},{"@id":"https://cir.nii.ac.jp/all?q=Brain","dc:title":"Brain"},{"@id":"https://cir.nii.ac.jp/all?q=Fear","dc:title":"Fear"},{"@id":"https://cir.nii.ac.jp/all?q=Amygdala","dc:title":"Amygdala"},{"@id":"https://cir.nii.ac.jp/all?q=Memory","dc:title":"Memory"},{"@id":"https://cir.nii.ac.jp/all?q=Neural%20Pathways","dc:title":"Neural 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