Circadian rhythms in human salivary flow rate and composition

書誌事項

公開日
1972-02
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1113/jphysiol.1972.sp009721
公開者
Wiley

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説明

<jats:p>1. Unstimulated whole saliva and parotid saliva stimulated at a constant flow rate of 1·0 ml./min were collected from eight subjects at about 07.00, 11.00, 14.00, 17.00 and 22.00 hr and oral temperature was recorded several times daily for time spans of between 4 and 26 days. A least‐squares cosine wave was fitted to the data to test for the presence and characteristics of circadian rhythms.</jats:p><jats:p>2. Estimates of mean level, amplitude, acrophase and period were obtained for different components and the results were subjected to cosinor analysis.</jats:p><jats:p>3. Unstimulated whole saliva showed significant circadian rhythms in flow rate and in the concentrations of sodium and chloride but not in protein, potassium, calcium, phosphate or urea.</jats:p><jats:p>4. Stimulated parotid saliva showed significant circadian rhythms in the concentrations of protein, sodium, potassium, calcium and chloride but not in phosphate or urea</jats:p><jats:p>5. Oral temperature showed a circadian rhythm which, like the salivary rhythms, was of a 24.0 hr periodicity.</jats:p>

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