{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362825894150631040.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1113/jphysiol.1972.sp009721"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1113%2Fjphysiol.1972.sp009721"}},{"identifier":{"@type":"URI","@value":"https://physoc.onlinelibrary.wiley.com/doi/pdf/10.1113/jphysiol.1972.sp009721"}}],"dc:title":[{"@value":"Circadian rhythms in human salivary flow rate and composition"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>1. Unstimulated whole saliva and parotid saliva stimulated at a constant flow rate of 1·0 ml./min were collected from eight subjects at about 07.00, 11.00, 14.00, 17.00 and 22.00 hr and oral temperature was recorded several times daily for time spans of between 4 and 26 days. A least‐squares cosine wave was fitted to the data to test for the presence and characteristics of circadian rhythms.</jats:p><jats:p>2. Estimates of mean level, amplitude, acrophase and period were obtained for different components and the results were subjected to cosinor analysis.</jats:p><jats:p>3. Unstimulated whole saliva showed significant circadian rhythms in flow rate and in the concentrations of sodium and chloride but not in protein, potassium, calcium, phosphate or urea.</jats:p><jats:p>4. Stimulated parotid saliva showed significant circadian rhythms in the concentrations of protein, sodium, potassium, calcium and chloride but not in phosphate or urea</jats:p><jats:p>5. Oral temperature showed a circadian rhythm which, like the salivary rhythms, was of a 24.0 hr periodicity.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380005521913186690","@type":"Researcher","foaf:name":[{"@value":"C. 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