{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362825894488339328.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1128/jcm.33.4.973-977.1995"}},{"identifier":{"@type":"URI","@value":"https://journals.asm.org/doi/pdf/10.1128/jcm.33.4.973-977.1995"}}],"dc:title":[{"@value":"Controlled study of Escherichia coli diarrheal infections in Bangladeshi children"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Diarrheal diseases are highly prevalent in Bangladesh. However, the relative contribution of diarrheagenic Escherichia coli organisms--those that are enterotoxigenic (ETEC), enteropathogenic (EPEC), enteroinvasive, enterohemorrhagic, enteroaggregative, and diffuse adherent--to diarrhea in Bangladeshi populations is not known. With DNA probes specific for these diarrheagenic E. coli strains, we analyzed fecal E. coli from 451 children up to 5 years of age with acute diarrhea seeking treatment at a Dhaka hospital and from 602 matched control children without diarrhea from July 1991 to May 1992. Enteroinvasive E. coli was not isolated from any children; enterohemorrhagic E. coli was not isolated from any diarrheal children but was isolated from five control children; enteroaggregative and diffuse adherent E. coli strains were isolated with similar frequencies from children with and without diarrhea, thereby showing no association with diarrhea; ETEC was significantly associated with diarrhea in the diarrheal children as a whole and especially in the age groups of 0 to 24 months and 37 to 48 months (further analysis suggests an association with diarrhea for the heat-stable toxin only and for both heat-labile- and heat-stable-toxin-producing ETEC only); and EPEC was significantly associated with diarrhea in the diarrhea group as a whole and particularly in infants up to 1 year of age. Further analysis suggested that EPEC strains of only the traditional serogroups were significantly associated with diarrhea. ETEC and EPEC infections peaked during warm months. Our data thus suggest that EPEC and ETEC are important causes of acute diarrhea in children in this setting.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380567186811098246","@type":"Researcher","foaf:name":[{"@value":"M J Albert"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]},{"@id":"https://cir.nii.ac.jp/crid/1382825894488339330","@type":"Researcher","foaf:name":[{"@value":"S M Faruque"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]},{"@id":"https://cir.nii.ac.jp/crid/1382825894488339329","@type":"Researcher","foaf:name":[{"@value":"A S Faruque"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]},{"@id":"https://cir.nii.ac.jp/crid/1382825894488339331","@type":"Researcher","foaf:name":[{"@value":"P K Neogi"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]},{"@id":"https://cir.nii.ac.jp/crid/1382825894488339335","@type":"Researcher","foaf:name":[{"@value":"M Ansaruzzaman"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]},{"@id":"https://cir.nii.ac.jp/crid/1382825894488339334","@type":"Researcher","foaf:name":[{"@value":"N A Bhuiyan"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]},{"@id":"https://cir.nii.ac.jp/crid/1382825894488339333","@type":"Researcher","foaf:name":[{"@value":"K Alam"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]},{"@id":"https://cir.nii.ac.jp/crid/1382825894488339328","@type":"Researcher","foaf:name":[{"@value":"M S Akbar"}],"jpcoar:affiliationName":[{"@value":"International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka."}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00951137"},{"@type":"EISSN","@value":"1098660X"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/00951137"}],"prism:publicationName":[{"@value":"Journal of Clinical Microbiology"}],"dc:publisher":[{"@value":"American Society for Microbiology"}],"prism:publicationDate":"1995-04","prism:volume":"33","prism:number":"4","prism:startingPage":"973","prism:endingPage":"977"},"reviewed":"false","dc:rights":["https://journals.asm.org/non-commercial-tdm-license"],"url":[{"@id":"https://journals.asm.org/doi/pdf/10.1128/jcm.33.4.973-977.1995"}],"createdAt":"2020-01-06","modifiedAt":"2022-03-05","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050287297240472448","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Prevalence, seasonal variation, and antibiotic resistance pattern of enteric bacterial pathogens among hospitalized diarrheic children in suburban regions of central Kenya"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680195099648","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"SHIGA-TOXIN PRODUCING ESCHERICHIA COLI IN VIETNAM"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680196212864","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"PREVALENCE AND CHARACTERISTICS OF <I>ESCHERICHIA COLI </I>ISOLATES HARBOURING SHIGA TOXIN GENES (<I>STX</I>) FROM ACUTE DIARRHOEAL PATIENTS IN DHAKA, BANGLADESH"},{"@value":"PREVALENCE AND CHARACTERISTICS OF ESCHERICHIA COLI ISOLATES HARBOURING SHIGA TOXIN GENES (STX) FROM ACUTE DIARRHOEAL PATIENTS IN DHAKA, BANGLADESH"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681216303744","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Burden of Rotavirus and Enteric Bacterial Pathogens among Children under 5 Years of Age Hospitalized with Diarrhea in Suburban and Rural Areas in Kenya"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681218080512","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"High Prevalence of Diarrheagenic <i>Escherichia coli</i> among Children with Diarrhea in Kenya"},{"@value":"High Prevalence of Diarrheagenic Escherichia coli among Children with Diarrhea in Kenya"}]},{"@id":"https://cir.nii.ac.jp/crid/1390846609798617088","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Prevalence of Virulence Genes of Diarrheagenic <i>Escherichia coli</i> in Fecal Samples Obtained from Cattle, Poultry and Diarrheic Patients in Bangladesh"},{"@value":"Epidemiological Report : Prevalence of Virulence Genes of Diarrheagenic Escherichia coli in Fecal Samples Obtained 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