{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1362825895416375680.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1055/s-2007-1016494"}},{"identifier":{"@type":"URI","@value":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-1016494.pdf"}},{"identifier":{"@type":"PMID","@value":"7825162"}},{"identifier":{"@type":"NAID","@value":"30041725994"}}],"dc:title":[{"@value":"Treatment of Postoperative Chylothorax by Pleurodesis with the Streptococcal Preparation OK-432"}],"description":[{"notation":[{"@value":"Of the 2877 patients who underwent chest surgery at our department during the 20-year period between 1973 and 1992, 9 (0.3%) developed postoperative chylothorax. The underlying disease included primary lung cancer in 5 patients, pulmonary metastasis in 1, invasive thymoma in 2, and neuroblastoma of the posterior mediastinum in 1. For the treatment of chylothorax, the thoracic duct was ligated in 2 patients with a high volume of chylous leakage. In 6 patients treated conservatively, early pleurodesis was attained by injecting 1 to 5 doses (mean: 2.2 doses) of the streptoccal preparation OK-432 intrathoracically; favorable results were achieved. In 1 patient, the diagnosis of chylothorax was delayed because of postoperative pyothorax. This patient developed nutritional deficiency, compromised immunity, and disseminated intravascular coagulation (DIC), which led to death before the chylothorax could be treated. In principle, postoperative chylothorax should be treated conservatively. Favorable results can be expected with the intrathoracic injection of OK-432 beginning at the early postoperative period to achieve pleurodesis, combined with the prevention of nutritional deficiency, electrolyte imbalance, and infection."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1582824501180713088","@type":"Researcher","foaf:name":[{"@value":"J. Shimizu"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375683","@type":"Researcher","foaf:name":[{"@value":"Y. Hayashi"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375684","@type":"Researcher","foaf:name":[{"@value":"M. Oda"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375680","@type":"Researcher","foaf:name":[{"@value":"K. Morita"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375552","@type":"Researcher","foaf:name":[{"@value":"Y. Arano"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375682","@type":"Researcher","foaf:name":[{"@value":"S. Nagao"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375681","@type":"Researcher","foaf:name":[{"@value":"S. Murakami"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375555","@type":"Researcher","foaf:name":[{"@value":"H. Urayama"}]},{"@id":"https://cir.nii.ac.jp/crid/1382825895416375554","@type":"Researcher","foaf:name":[{"@value":"Y. Watanabe"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"01716425"},{"@type":"EISSN","@value":"14391902"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/09672109"}],"prism:publicationName":[{"@value":"The Thoracic and Cardiovascular Surgeon"}],"dc:publisher":[{"@value":"Georg Thieme Verlag KG"}],"prism:publicationDate":"1994-08","prism:volume":"42","prism:number":"04","prism:startingPage":"233","prism:endingPage":"236"},"reviewed":"false","url":[{"@id":"http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-1016494.pdf"}],"createdAt":"2008-11-07","modifiedAt":"2017-05-22","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Adult","dc:title":"Adult"},{"@id":"https://cir.nii.ac.jp/all?q=Male","dc:title":"Male"},{"@id":"https://cir.nii.ac.jp/all?q=Infant","dc:title":"Infant"},{"@id":"https://cir.nii.ac.jp/all?q=Thoracic%20Surgery","dc:title":"Thoracic Surgery"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Chylothorax","dc:title":"Chylothorax"},{"@id":"https://cir.nii.ac.jp/all?q=Picibanil","dc:title":"Picibanil"},{"@id":"https://cir.nii.ac.jp/all?q=Postoperative%20Complications","dc:title":"Postoperative Complications"},{"@id":"https://cir.nii.ac.jp/all?q=Treatment%20Outcome","dc:title":"Treatment Outcome"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"},{"@id":"https://cir.nii.ac.jp/all?q=Pleurodesis","dc:title":"Pleurodesis"},{"@id":"https://cir.nii.ac.jp/all?q=Aged","dc:title":"Aged"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004231199176960","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Radiofrequency Ablation of Liver Tumors in Combination with Local OK-432 Injection Prolongs Survival and Suppresses Distant Tumor Growth in the Rabbit Model with Intra- and Extrahepatic VX2 Tumors"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285706969892096","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Indocyanine Green Lymphography and Lymphaticovenous Anastomosis for Generalized Lymphatic Dysplasia with Pleural Effusion and Ascites in Neonates"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567181268246528","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Successful treatment of chylothorax after esophagectomy using octreotide and etilefrine"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567185569687808","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Fluid overload deteriorate chylothorax: evaluation in a canine model"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204362326400","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Review of postoperative chylothorax after lung resection with lymph node dissection"},{"@language":"ja","@value":"肺癌術後乳糜胸についての臨床的検討"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679337304192","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Octreotide for treating chylothorax after thoracic surgery"},{"@language":"ja","@value":"オクトレオチドが有効であった術後乳糜胸の一例"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679338197888","@type":"Article","relationType":["isReferencedBy","isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Early endoscopic treatment of postoperative chylothorax"},{"@language":"ja","@value":"術後乳び胸に対する胸腔鏡下手術の４例"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1055/s-2007-1016494"},{"@type":"CIA","@value":"30041725994"},{"@type":"OPENAIRE","@value":"doi_dedup___::0c139bb57da8334292b769921f022f7a"},{"@type":"CROSSREF","@value":"10.1007/s00270-013-0650-y_references_DOI_YyGKcnhB9fABT7gkLuWwcJlpzEj"},{"@type":"CROSSREF","@value":"10.2995/jacsurg.25.635_references_DOI_YyGKcnhB9fABT7gkLuWwcJlpzEj"},{"@type":"CROSSREF","@value":"10.1007/s10388-016-0526-8_references_DOI_YyGKcnhB9fABT7gkLuWwcJlpzEj"},{"@type":"CROSSREF","@value":"10.1111/j.1442-2050.2011.01237.x_references_DOI_YyGKcnhB9fABT7gkLuWwcJlpzEj"},{"@type":"CROSSREF","@value":"10.1016/j.avsg.2015.02.013_references_DOI_YyGKcnhB9fABT7gkLuWwcJlpzEj"},{"@type":"CROSSREF","@value":"10.2995/jacsurg.23.120_references_DOI_YyGKcnhB9fABT7gkLuWwcJlpzEj"},{"@type":"CROSSREF","@value":"10.2995/jacsurg.19.562_references_DOI_YyGKcnhB9fABT7gkLuWwcJlpzEj"}]}