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- Todd Thorsen
- Biochemistry and Molecular Biophysics Option,
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- Sebastian J. Maerkl
- Biochemistry and Molecular Biophysics Option,
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- Stephen R. Quake
- Department of Applied Physics, California Institute of Technology, Pasadena, CA 91125, USA.
説明
<jats:p>We developed high-density microfluidic chips that contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large-scale integration. A key component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. We used these integrated microfluidic networks to construct the microfluidic analog of a comparator array and a microfluidic memory storage device whose behavior resembles random-access memory.</jats:p>
収録刊行物
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- Science
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Science 298 (5593), 580-584, 2002-10-18
American Association for the Advancement of Science (AAAS)