{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363388843350583296.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/hed.2880160211"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fhed.2880160211"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/hed.2880160211"}}],"dc:title":[{"@value":"Locally invasive papillary thyroid carcinoma: 1940–1990"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>Well‐differentiated thyroid carcinoma infrequently invades the upper aerodigestive tract. However, when invasion occurs, it is the source of significant morbidity. The most common structures invaded by thyroid carcinoma are the recurrent laryngeal nerves, larynx, pharynx, and esophagus. Invasion of these structures produces symptoms of airway insufficiency, dysphagia, and hemoptysis.</jats:p><jats:p>This study was designed to define more clearly the significance of invasion of papillary thyroid carcinoma on survival. At the Mayo Clinic, 262 patients treated for invasive papillary thyroid carcinoma between 1940 and 1990 were retrospectively evaluated. In this group the sites of invasion were muscle 53%, trachea 37%, laryngeal nerve 47%, esophagus 21%, larynx 12%, and other sites 30%. Complete tumor removal was accomplished in 56% of cases. Kaplan‐Meier survival curves were calculated for the population. The over‐all survival was 79% at 5 years, 63% at 10 years, and 54% at 15 years. When the Cox proportional hazard model was applied to the survival data, the factors that had significant influence on survival were invasion of the trachea and the esophagus. Completeness of resection approached statistical significance. Muscle invasion, laryngeal invasion, and recurrent laryngeal nerve invasion had no significant independent influence on survival. These data suggest that when papillary thyroid carcinoma extends beyond the thyroid capsule and invades adjacent structures, the site invaded will influence survival. Survival may be improved in those cases in which complete surgical excision of the tumor is performed. © 1994 John Wiley & Sons, Inc.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383388843350583425","@type":"Researcher","foaf:name":[{"@value":"Thomas V. McCaffrey"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843350583424","@type":"Researcher","foaf:name":[{"@value":"Erik J. Bergstralh"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843350583426","@type":"Researcher","foaf:name":[{"@value":"Ian D. Hay"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"10433074"},{"@type":"EISSN","@value":"10970347"}],"prism:publicationName":[{"@value":"Head & Neck"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"1994-03","prism:volume":"16","prism:number":"2","prism:startingPage":"165","prism:endingPage":"172"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fhed.2880160211"},{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/hed.2880160211"}],"createdAt":"2007-02-21","modifiedAt":"2023-10-23","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360298757180822656","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Surgical strategy of locally advanced differentiated thyroid cancer"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205014541952","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Management of Thyroid Cancer Involving the Laryngotracheal Complex"},{"@language":"ja","@value":"浸潤性甲状腺癌の管理について"},{"@value":"Invitation Lecture : Management of Thyroid Cancer Involving the Laryngotracheal Complex"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205282914048","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Our experience of one-stage resection and reconstruction for thyroid cancer invading the larynx and/or trachea"},{"@language":"ja","@value":"甲状腺癌気道（気管・喉頭）内腔浸潤の一期的切除再建"}]},{"@id":"https://cir.nii.ac.jp/crid/1390002184889689088","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Recurrent thyroid cancer with thyroid cartilage invasion treated with larynx preservation surgery"},{"@language":"ja","@value":"甲状軟骨浸潤を認める再発甲状腺癌に対し 喉頭温存手術を施行した1例"}]},{"@id":"https://cir.nii.ac.jp/crid/1390022620392236032","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The 2024 revised clinical guidelines on the management of thyroid tumors by the Japan Association of Endocrine Surgery"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679989679104","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"甲状腺分化癌の外科的治療と分子標的薬"},{"@value":"第117回日本耳鼻咽喉科学会総会ランチョンセミナー 甲状腺分化癌の外科的治療と分子標的薬 : 局所進行甲状腺癌の手術療法"},{"@language":"ja-Kana","@value":"ダイ117カイ ニホン ジビ インコウ カガクカイ ソウカイ ランチョンセミナー コウジョウセン ブンカガン ノ ゲカテキ チリョウ ト ブンシ ヒョウテキヤク : キョクショ シンコウ コウジョウセン ガン ノ シュジュツ リョウホウ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390579522006203648","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"進行甲状腺癌の外科的治療"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/hed.2880160211"},{"@type":"CROSSREF","@value":"10.2468/jbes.63.84_references_DOI_MxUfO1ZsJjx176eghhIuHd08cD0"},{"@type":"CROSSREF","@value":"10.5106/jjshns.23.393_references_DOI_MxUfO1ZsJjx176eghhIuHd08cD0"},{"@type":"CROSSREF","@value":"10.5106/jjshns.33.125_references_DOI_MxUfO1ZsJjx176eghhIuHd08cD0"},{"@type":"CROSSREF","@value":"10.1016/j.anl.2022.03.005_references_DOI_MxUfO1ZsJjx176eghhIuHd08cD0"},{"@type":"CROSSREF","@value":"10.1507/endocrj.ej24-0644_references_DOI_MxUfO1ZsJjx176eghhIuHd08cD0"},{"@type":"CROSSREF","@value":"10.5106/jjshns.29.321_references_DOI_MxUfO1ZsJjx176eghhIuHd08cD0"},{"@type":"CROSSREF","@value":"10.3950/jibiinkoka.119.1496_references_DOI_MxUfO1ZsJjx176eghhIuHd08cD0"}]}