{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363388843611920128.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/anie.202014080"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202014080"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/anie.202014080"}}],"dc:title":[{"@value":"Rhodium‐Catalyzed Enantioselective Synthesis of β‐Amino Alcohols via Desymmetrization of <i>gem</i>‐Dimethyl Groups"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>Desymmetrization of <jats:italic>gem</jats:italic>‐dimethyl groups en route to the rhodium(III)‐catalyzed enantioselective sp<jats:sup>3</jats:sup> C−H amidation is reported. Synthetically important β‐amino alcohol derivatives were accessed in moderate to good yields and high enantioselectivity. The high enantioselectivity is enabled by an appropriate oxime directing group, sterically biased <jats:italic>gem</jats:italic>‐groups in the C−H substrate, and high reactivity of the amidating reagent.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383388843611920129","@type":"Researcher","foaf:name":[{"@value":"Bingxian Liu"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843611920128","@type":"Researcher","foaf:name":[{"@value":"Pengfei Xie"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843611920002","@type":"Researcher","foaf:name":[{"@value":"Jie Zhao"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843611920001","@type":"Researcher","foaf:name":[{"@value":"Juanjuan Wang"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843611920130","@type":"Researcher","foaf:name":[{"@value":"Manman Wang"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843611920000","@type":"Researcher","foaf:name":[{"@value":"Yuqin Jiang"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843611920131","@type":"Researcher","foaf:name":[{"@value":"Junbiao Chang"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843611920003","@type":"Researcher","foaf:name":[{"@value":"Xingwei Li"}],"jpcoar:affiliationName":[{"@value":"Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 China"},{"@value":"School of Chemistry and Chemical Engineering Shaanxi Normal University (SNNU)  Xi'an 710062 China"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"14337851"},{"@type":"EISSN","@value":"15213773"}],"prism:publicationName":[{"@value":"Angewandte Chemie International Edition"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2021-03","prism:volume":"60","prism:number":"15","prism:startingPage":"8396","prism:endingPage":"8400"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202014080"},{"@id":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/anie.202014080"}],"createdAt":"2020-12-18","modifiedAt":"2023-09-02","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050587981426805632","@type":"Article","resourceType":"学術雑誌論文(journal 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Activation with Achiral Cp<sup>x</sup>M<sup>III</sup> (M = Co, Rh, Ir) Catalysts"}]},{"@id":"https://cir.nii.ac.jp/crid/2050307417131935488","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Enantioselective C-H functionalization using high-valent group 9 metal catalysts"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/anie.202014080"},{"@type":"CROSSREF","@value":"10.1002/anie.202213659_references_DOI_MAMfWU6MRZGZ0zflpmfcsvj8q7X"},{"@type":"CROSSREF","@value":"10.1021/acscatal.1c00765_references_DOI_MAMfWU6MRZGZ0zflpmfcsvj8q7X"},{"@type":"CROSSREF","@value":"10.1021/acscatal.1c01351_references_DOI_MAMfWU6MRZGZ0zflpmfcsvj8q7X"},{"@type":"CROSSREF","@value":"10.1246/bcsj.20220168_references_DOI_MAMfWU6MRZGZ0zflpmfcsvj8q7X"}]}