{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363388843650670592.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1161/01.cir.96.10.3273"}},{"identifier":{"@type":"URI","@value":"https://www.ahajournals.org/doi/full/10.1161/01.CIR.96.10.3273"}}],"dc:title":[{"@value":"Evaluation of Different Ventricular Pacing Sites in Patients With Severe Heart Failure"}],"dcterms:alternative":[{"@value":"Results of an Acute Hemodynamic Study"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>\n            <jats:italic>Background</jats:italic>\n            Multisite ventricular pacing has recently been proposed as an additional treatment for patients with severe congestive heart failure. To further assess the potential value of this technique, we compared the acute hemodynamic changes associated with pacing the right ventricular apex (RVA) or outflow tract (RVOT) alone, the left ventricle (LV) alone, or biventricular (BIV) pacing of the RVA and LV together.\n          </jats:p>\n          <jats:p>\n            <jats:italic>Methods and Results</jats:italic>\n            Acute hemodynamic findings were measured in 27 patients with severe heart failure despite optimal therapy and either first-degree AV block and/or an intraventricular conduction defect. In the 23 patients with a high pulmonary capillary wedge pressure (PCWP) (>15 mm Hg), data were collected after transvenous pacing at different ventricular sites in either the VDD mode (AV delay=100 ms) or the VVI mode in patients with atrial fibrillation (n=6). The mean baseline cardiac index was 1.82 L · min\n            <jats:sup>−1</jats:sup>\n            · m\n            <jats:sup>−2</jats:sup>\n            . Mean±SD baseline systolic blood pressure (SBP) (118.5±15.2 mm Hg), PCWP (26.4±6.6 mm Hg), and V-wave amplitude (39.1±14.6 mm Hg) were similar before and after either RVA or RVOT pacing. In contrast, LV-based pacing (either LV alone or BIV pacing) resulted in higher SBP (\n            <jats:italic>P</jats:italic>\n            <.03) and lower PCWP (\n            <jats:italic>P</jats:italic>\n            <.01) and V-wave amplitude (\n            <jats:italic>P</jats:italic>\n            <.001) than either baseline or RV pacing measurements. With LV pacing alone, SBP, PCWP, and V waves were 126.5±15.1, 20.7±5.9, and 25.5±8.1 mm Hg, respectively. The results with LV pacing alone were similar to those obtained with BIV pacing.\n          </jats:p>\n          <jats:p>\n            <jats:italic>Conclusions</jats:italic>\n            In patients with severe congestive heart failure, both LV pacing alone and BIV pacing resulted in a similar and significant acute improvement in SBP, PCWP, and V-wave amplitude compared with baseline measurements and RV pacing alone. These results provide a strong basis for initiating long-term studies examining the chronic effects of LV-based pacing in patients with medically refractory congestive heart failure.\n          </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383388843650670598","@type":"Researcher","foaf:name":[{"@value":"Jean-Jacques Blanc"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843650670594","@type":"Researcher","foaf:name":[{"@value":"Yves Etienne"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843650670595","@type":"Researcher","foaf:name":[{"@value":"Martine Gilard"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843650670599","@type":"Researcher","foaf:name":[{"@value":"Jacques Mansourati"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843650670597","@type":"Researcher","foaf:name":[{"@value":"Stéphane Munier"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843650670596","@type":"Researcher","foaf:name":[{"@value":"Jacques Boschat"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843650670592","@type":"Researcher","foaf:name":[{"@value":"David G. Benditt"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]},{"@id":"https://cir.nii.ac.jp/crid/1383388843650670593","@type":"Researcher","foaf:name":[{"@value":"Keith G. Lurie"}],"jpcoar:affiliationName":[{"@value":"From the Department of Cardiology, Brest (France) University Hospital (J.-J.B., Y.E., M.G., J.M., S.M., J.B.) and the Cardiac Arrhythmia Center, University of Minnesota, Minneapolis (D.G.B., K.G.L.)."}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00097322"},{"@type":"EISSN","@value":"15244539"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/00097322"}],"prism:publicationName":[{"@value":"Circulation"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"1997-11-18","prism:volume":"96","prism:number":"10","prism:startingPage":"3273","prism:endingPage":"3277"},"reviewed":"false","url":[{"@id":"https://www.ahajournals.org/doi/full/10.1161/01.CIR.96.10.3273"}],"createdAt":"2012-06-12","modifiedAt":"2024-05-12","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360846643658821120","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Cardiac Resynchronization Therapy Improves Altered Na Channel Gating in Canine Model of Dyssynchronous Heart Failure"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848656218410624","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Pacing device therapy in infants and children: a review"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204239700480","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effect of Cardiac Resynchronization Therapy on Left Atrial Reverse Remodeling and Spontaneous Echo Contrast"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205102494976","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Relationship Between Asynchronous Myocardial Contraction and Left Ventricular Systolic and Diastolic Function-Assessment Using the ECG-Gated Polar Map With 99mTc-Methoxy-Isobutyl Isonitrile-"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282763010675712","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"両室ぺーシング(<特集II>第66回日本循環器学会学術集会)"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1161/01.cir.96.10.3273"},{"@type":"CROSSREF","@value":"10.1161/circep.113.000400_references_DOI_CkKrW4hKGSY4Tj3n14fYph6IlPe"},{"@type":"CROSSREF","@value":"10.1007/s10047-012-0668-y_references_DOI_CkKrW4hKGSY4Tj3n14fYph6IlPe"},{"@type":"CROSSREF","@value":"10.1253/circj.69.183_references_DOI_CkKrW4hKGSY4Tj3n14fYph6IlPe"},{"@type":"CROSSREF","@value":"10.1620/tjem.202.143_references_DOI_CkKrW4hKGSY4Tj3n14fYph6IlPe"},{"@type":"CROSSREF","@value":"10.1253/jjcsc.11.1_81_references_DOI_CkKrW4hKGSY4Tj3n14fYph6IlPe"}]}