{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363388844589709824.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.tetlet.2007.07.051"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S004040390701355X?httpAccept=text/xml"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S004040390701355X?httpAccept=text/plain"}}],"dc:title":[{"@value":"Synthetic studies on (–)-FR182877: construction of the ABCD ring system via the intramolecular cycloadditions (1)"}],"description":[{"notation":[{"@value":"Abstract   Construction of the ABCD ring system of (–)-FR182877 via the highly diastereoselective intramolecular Diels–Alder (IMDA) reaction is described. The IMDA reaction of the α,β-unsaturated aldehyde generated in situ from the corresponding acetal successfully provided the desired product 14 possessing the AB ring system as the single diastereomer. The CD ring system was constructed by the subsequent IMHDA reaction and the additional experiment suggested that the diastereoselectivity of the IMHDA reaction could be related to the E/Z geometry of alkene 17, which was generated in situ from 16."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383388844589709827","@type":"Researcher","foaf:name":[{"@value":"Takahiro Suzuki"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388844589709952","@type":"Researcher","foaf:name":[{"@value":"Natsumi Tanaka"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388844589709824","@type":"Researcher","foaf:name":[{"@value":"Takehiko Matsumura"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388844589709825","@type":"Researcher","foaf:name":[{"@value":"Yosuke Hosoya"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388844589709826","@type":"Researcher","foaf:name":[{"@value":"Masahisa Nakada"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00404039"}],"prism:publicationName":[{"@value":"Tetrahedron Letters"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2007-09","prism:volume":"48","prism:number":"37","prism:startingPage":"6483","prism:endingPage":"6487"},"reviewed":"false","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S004040390701355X?httpAccept=text/xml"},{"@id":"https://api.elsevier.com/content/article/PII:S004040390701355X?httpAccept=text/plain"}],"createdAt":"2007-07-14","modifiedAt":"2019-01-06","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360285707504769792","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Research on Liebeskind-Srogl coupling/intramolecular Diels-Alder reaction cascade"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285708226108544","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Asymmetric and Highly Stereoselective Synthesis of the DEF-Ring Moiety of (−)-FR182877 and Its Derivative Inducing Mitotic Arrest"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567182481139584","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A highly stereoselective intramolecular Diels–Alder reaction for construction of the AB ring moiety of bruceantin"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205339707264","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Enantioselective Total Synthesis of (-)-FR182877"},{"@language":"ja","@value":"（－）‐ＦＲ１８２８７７の不斉全合成"},{"@value":"(-)-FR182877の不斉全合成"},{"@language":"ja-Kana","@value":"FR182877 ノ フセイ ゼンゴウセイ"},{"@value":"ChemInform Abstract: Enantioselective Total Synthesis of (‐)‐FR182877"}]},{"@id":"https://cir.nii.ac.jp/crid/1881428067803586304","@type":"Dataset","relationType":["isSupplementedBy"],"jpcoar:relatedTitle":[{"@value":"CCDC 650070: Experimental Crystal Structure Determination"}]},{"@id":"https://cir.nii.ac.jp/crid/2050025942155224064","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Research on the efficient enantioselective total synthesis of useful bioactive polycyclic compounds"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2007.07.051"},{"@type":"OPENAIRE","@value":"doi_dedup___::d1577076513dcc1d861461e3d2bc3323"},{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2015.01.139_references_DOI_MKKmCxX21lTTymctxaj88pAYp33"},{"@type":"CROSSREF","@value":"10.1246/bcsj.20210329_references_DOI_MKKmCxX21lTTymctxaj88pAYp33"},{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2018.01.046_references_DOI_MKKmCxX21lTTymctxaj88pAYp33"},{"@type":"CROSSREF","@value":"10.5059/yukigoseikyokaishi.69.646_references_DOI_MKKmCxX21lTTymctxaj88pAYp33"},{"@type":"CROSSREF","@value":"10.1021/ol300615w_references_DOI_MKKmCxX21lTTymctxaj88pAYp33"}]}