{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363388845754375296.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/lt.21606"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Flt.21606"}},{"identifier":{"@type":"URI","@value":"https://journals.lww.com/01445473-200905000-00007"}}],"dc:title":[{"@value":"Improved outcome of adult recipients with a high model for end-stage liver disease score and a small-for-size graft"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:sec>\n            <jats:title/>\n            <jats:p>Although adult-to-adult living donor liver transplantation (ALDLT) has shown comparable outcomes to deceased donor liver transplantation, the outcome of patients with a high MELD score (>25) and a small-for-size graft (SFSG<0.8% of graft-to-recipient weight ratio) is not known. For 7 years, 167 consecutive hepatitis B virus-infected recipients underwent ALDLT at our institution. Based on their MELD score without additional score for hepatocellular carcinoma (HCC), the recipients were divided into Group L (low MELD score, n = 105) or Group H (high MELD score, n = 62). To analyze the risk of the graft size, the patients were further stratified as follows: Group Hs (high MELD score and SFSG, n = 11), Hn (high MELD score and normal size graft, n = 51), Ls (low MELD score and SFSG, n = 18), and Ln (low MELD score and normal size graft, n = 87). The primary endpoint was one-year patient survival rate (1-YSR). The mean follow-up period was 32.6 months. The mean MELD scores were 17.1 in Group L and 32.6 in Group H. Group H had more patients with the complications of cirrhosis but less patients with HCC than Group L (p < 0.05). However, major morbidity rates and 1-YSR were similar in comparisons between Group L (46.7% and 86.7%) and H (59.7% and 83.8%) (p > 0.05). 1-YSR was similar among Group Hs (72.7%), Hn (86.3%), Ls (83.3%), and Ln (88.5%) groups (p = 0.278). The multivariate analysis revealed accompanying HCC and the year of transplant were risk factors for poor 1-YSR. However, 1-YSR without HCC patients was also similar in comparisons between group L (90.2%) and H (91.7%) (p = 0.847), and among Group Hs (80.0%), Hn (94.7%), Ls (72.7%), and Ln (96.7%) (p = 0.072). In conclusion, high MELD score (>25) didn't predict 1-YSR in ALDLT. Improvement of the 1-YSR might be affected by center's experience as well as the selection of patients with low risk of recurrence of HCC.</jats:p>\n          </jats:sec>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383388845754375301","@type":"Researcher","foaf:name":[{"@value":"Nam-Joon Yi"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375302","@type":"Researcher","foaf:name":[{"@value":"Kyung-Suk Suh"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375298","@type":"Researcher","foaf:name":[{"@value":"Hae Won Lee"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375299","@type":"Researcher","foaf:name":[{"@value":"Woo Young Shin"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375303","@type":"Researcher","foaf:name":[{"@value":"Juhyun Kim"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375305","@type":"Researcher","foaf:name":[{"@value":"Won Kim"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375297","@type":"Researcher","foaf:name":[{"@value":"Yoon Jun Kim"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375300","@type":"Researcher","foaf:name":[{"@value":"Jung-Hwan Yoon"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375304","@type":"Researcher","foaf:name":[{"@value":"Hyo-Suk Lee"}]},{"@id":"https://cir.nii.ac.jp/crid/1383388845754375296","@type":"Researcher","foaf:name":[{"@value":"Kuhn Uk Lee"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"15276465"}],"prism:publicationName":[{"@value":"Liver Transplantation"}],"dc:publisher":[{"@value":"Ovid Technologies (Wolters Kluwer Health)"}],"prism:publicationDate":"2009-05","prism:volume":"15","prism:number":"5","prism:startingPage":"496","prism:endingPage":"503"},"reviewed":"false","dc:rights":["http://doi.wiley.com/10.1002/tdm_license_1.1","http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Flt.21606"},{"@id":"https://journals.lww.com/01445473-200905000-00007"}],"createdAt":"2009-04-27","modifiedAt":"2025-03-30","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360285705187515392","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Etiologies, risk factors, and outcomes of bacterial pneumonia after living donor liver transplantation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360290617624637440","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Small‐for‐size graft, small‐for‐size syndrome and inflow modulation in living donor liver transplantation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360298754811338752","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Is 0.6% Reasonable as the Minimum Requirement of the Graft-to-recipient Weight Ratio Regardless of Lobe Selection in Adult Living-donor Liver Transplantation?"}]},{"@id":"https://cir.nii.ac.jp/crid/1360298757420495360","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Which recipient pretransplant factors, such as MELD, renal function, sarcopenia, and recent sepsis influence suitability for and outcome after living donor liver transplantation? A systematic review of the literature and expert panel recommendations"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567181220448640","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Small-for-size syndrome in living-donor liver transplantation using a left lobe graft"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567185666225152","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Primary Graft Dysfunction After Living Donor Liver Transplantation Is Characterized by Delayed Functional Hyperbilirubinemia"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/lt.21606"},{"@type":"CROSSREF","@value":"10.1002/lt.23483_references_DOI_R3uOAOe7g6UFqYwsJ0veivGAGd6"},{"@type":"CROSSREF","@value":"10.1002/jhbp.822_references_DOI_R3uOAOe7g6UFqYwsJ0veivGAGd6"},{"@type":"CROSSREF","@value":"10.1097/tp.0000000000003472_references_DOI_R3uOAOe7g6UFqYwsJ0veivGAGd6"},{"@type":"CROSSREF","@value":"10.1111/ctr.14656_references_DOI_R3uOAOe7g6UFqYwsJ0veivGAGd6"},{"@type":"CROSSREF","@value":"10.1007/s00595-014-0945-x_references_DOI_R3uOAOe7g6UFqYwsJ0veivGAGd6"},{"@type":"CROSSREF","@value":"10.1111/j.1600-6143.2012.04052.x_references_DOI_R3uOAOe7g6UFqYwsJ0veivGAGd6"}]}