{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670319087893248.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1021/ja020510o"}},{"identifier":{"@type":"URI","@value":"https://pubs.acs.org/doi/pdf/10.1021/ja020510o"}}],"dc:title":[{"@value":"Formation of Silver(I)-Mediated DNA Duplex and Triplex through an Alternative Base Pair of Pyridine Nucleobases"}],"description":[{"notation":[{"@value":"We have recently reported the first artificial nucleoside for alternative DNA base pairing through metal complexation (J. Org. Chem. 1999, 64, 5002-5003). In this context, we have accomplished a Ag(I)-mediated base pair or a base triplet in a double- or triple-stranded DNA, respectively, by introducing a pair of pyridine nucleobases in the middle of the sequence. As a result, the incorporated Ag(I) complex significantly stabilized the DNA duplex and triplex. This strategy would be expanded to the regulation of thermodynamic stability of DNA duplex or triplex by adding transition metal ions from outside, or to labeling applications in biotechnology."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670319087893248","@type":"Researcher","foaf:name":[{"@value":"Kentaro Tanaka"}],"jpcoar:affiliationName":[{"@value":"Contribution from the Department of Chemistry, Graduate School of Science, the University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319087893250","@type":"Researcher","foaf:name":[{"@value":"Yasuyuki Yamada"}],"jpcoar:affiliationName":[{"@value":"Contribution from the Department of Chemistry, Graduate School of Science, the University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319087893249","@type":"Researcher","foaf:name":[{"@value":"Mitsuhiko Shionoya"}],"jpcoar:affiliationName":[{"@value":"Contribution from the Department of Chemistry, Graduate School of Science, the University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00027863"},{"@type":"EISSN","@value":"15205126"}],"prism:publicationName":[{"@value":"Journal of the American Chemical Society"}],"dc:publisher":[{"@value":"American Chemical Society (ACS)"}],"prism:publicationDate":"2002-07-01","prism:volume":"124","prism:number":"30","prism:startingPage":"8802","prism:endingPage":"8803"},"reviewed":"false","url":[{"@id":"https://pubs.acs.org/doi/pdf/10.1021/ja020510o"}],"createdAt":"2002-09-17","modifiedAt":"2021-09-23","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004229919042944","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal‐Locked DNA Three‐Way Junction"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004232521574912","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Positive cooperativity of the specific binding between Hg2+ ion and T:T mismatched base pairs in duplex DNA"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004233564547968","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal ion-binding properties of DNA duplexes containing thiopyrimidine base pairs"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004239506682752","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Specific Binding of Anionic Porphyrin and Phthalocyanine to the G-Quadruplex with a Variety of in Vitro and in Vivo Applications"}]},{"@id":"https://cir.nii.ac.jp/crid/1360005514549904000","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Silver(I)‐Ion‐Mediated Cytosine‐Containing Base Pairs: Metal Ion Specificity for Duplex Stabilization and Susceptibility toward DNA Polymerases"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285706981748608","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Thermodynamic and structural properties of the specific binding between Ag+ ion and C:C mismatched base pair in duplex DNA to form C–Ag–C metal-mediated base pair"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285709646757632","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Raman spectroscopic detection of the T-Hg II -T base pair and the ionic characteristics of mercury"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565164377900032","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Regulated Incorporation of Two Different Metal Ions into Programmed Sites in a Duplex by DNA Polymerase Catalyzed Primer Extension"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565164378562816","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"High‐Resolution Crystal Structure of a Silver(I)–RNA Hybrid Duplex Containing Watson–Crick‐like CSilver(I)C Metallo‐Base Pairs"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567189446525312","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The Effects of Magnesium Ions on the Enzymatic Synthesis of Ligand-Bearing Artificial DNA by Template-Independent Polymerase"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576118673351296","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Bipyridine‐Modified DNA Three‐Way Junctions with Amide linkers: Metal‐Dependent Structure Induction and Self‐Sorting"}]},{"@id":"https://cir.nii.ac.jp/crid/1360576148815184384","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-mediated DNA base pairing of easily prepared 2-oxo-imidazole-4-carboxylate nucleotides"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846641548643968","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-Mediated DNA Base Pairing: Alternatives to Hydrogen-Bonded Watson–Crick Base Pairs"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848658541598080","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-responsive structural transformation between artificial DNA duplexes and three-way junctions"}]},{"@id":"https://cir.nii.ac.jp/crid/1360853567834119040","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Metal-responsive reversible binding of triplex-forming oligonucleotides with 5-hydroxyuracil nucleobases"}]},{"@id":"https://cir.nii.ac.jp/crid/1360869855561274112","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Phenanthroline-modified DNA three-way junction structures stabilized by interstrand 3 : 1 metal complexation"}]},{"@id":"https://cir.nii.ac.jp/crid/1361976069080698112","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Supramolecular DNA Three-Way Junction Motifs With a Bridging Metal Center"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204586198400","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Bio-inspired Programmable Self-assembly on DNA Templates"},{"@value":"Bio‐Inspired Programmable Self‐Assembly on DNA Templates"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001206535729408","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Structure of Metallo-DNA Duplex"},{"@language":"ja","@value":"新規ナノデバイス材料としてのメタロＤＮＡ分子の構造"},{"@language":"ja-Kana","@value":"シンキ ナノデバイス ザイリョウ ト シテノ メタロ DNA ブンシ ノ コウゾウ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390002184881227648","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Supraspace Chemistry: Molecular Array, Reactions, In-situ Observation"},{"@language":"ja","@value":"超空間化学：分子配列・反応・その場観察"},{"@value":"Award Accounts 超空間化学 : 分子配列・反応・その場観察"},{"@language":"ja-Kana","@value":"Award Accounts チョウクウカン カガク : ブンシ ハイレツ ・ ハンノウ ・ ソノ バ カンサツ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390305721533459584","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effects of pH and 5-Substitution of Templated Thymine on Metal-Mediated Primer Extension Reaction by DNA Polymerases: Insights into Base Selectivity of Metal Ions"}]},{"@id":"https://cir.nii.ac.jp/crid/2050025942141186048","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Artificial DNA base pairing mediated by diverse metal ions"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1021/ja020510o"},{"@type":"OPENAIRE","@value":"doi_dedup___::6e02ae3217a491bfe18e105333a6b962"},{"@type":"CROSSREF","@value":"10.1002/anie.201207338_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1039/c2cc15436f_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.3390/molecules170910586_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1002/cbic.201900450_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1021/ar200313h_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1248/cpb.c25-00390_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1093/nar/gks208_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1246/cl.160985_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1002/anie.201311235_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1002/anie.201507894_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.3390/ijms17060906_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1016/j.biochi.2012.06.024_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.2142/biophys.48.119_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1002/chem.202102977_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1039/d2sc00926a_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1039/c6sc00383d_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1246/cl.2006.694_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1039/d1cc00553g_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1039/d3dt01508d_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.4019/bjscc.74.3_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.1016/j.tca.2011.03.018_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"},{"@type":"CROSSREF","@value":"10.3389/fchem.2019.00925_references_DOI_TVVqH0Uo5nafrzSZrwSIe2rAlDp"}]}