{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670319097079936.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1016/j.jaci.2015.01.046"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0091674915002651?httpAccept=text/plain"}},{"identifier":{"@type":"URI","@value":"https://api.elsevier.com/content/article/PII:S0091674915002651?httpAccept=text/xml"}}],"dc:title":[{"@value":"Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670319097080064","@type":"Researcher","foaf:name":[{"@value":"Coen H. Wiegman"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079947","@type":"Researcher","foaf:name":[{"@value":"Charalambos Michaeloudes"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079948","@type":"Researcher","foaf:name":[{"@value":"Gulammehdi Haji"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079946","@type":"Researcher","foaf:name":[{"@value":"Priyanka Narang"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079939","@type":"Researcher","foaf:name":[{"@value":"Colin J. Clarke"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079954","@type":"Researcher","foaf:name":[{"@value":"Kirsty E. Russell"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079938","@type":"Researcher","foaf:name":[{"@value":"Wuping Bao"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079942","@type":"Researcher","foaf:name":[{"@value":"Stelios Pavlidis"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079937","@type":"Researcher","foaf:name":[{"@value":"Peter J. Barnes"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079943","@type":"Researcher","foaf:name":[{"@value":"Justin Kanerva"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079950","@type":"Researcher","foaf:name":[{"@value":"Anton Bittner"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079941","@type":"Researcher","foaf:name":[{"@value":"Navin Rao"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079940","@type":"Researcher","foaf:name":[{"@value":"Michael P. Murphy"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079936","@type":"Researcher","foaf:name":[{"@value":"Paul A. Kirkham"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097080065","@type":"Researcher","foaf:name":[{"@value":"Kian Fan Chung"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079808","@type":"Researcher","foaf:name":[{"@value":"Ian M. Adcock"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079956","@type":"Researcher","foaf:name":[{"@value":"Christopher E. Brightling"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079945","@type":"Researcher","foaf:name":[{"@value":"Donna E. Davies"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079944","@type":"Researcher","foaf:name":[{"@value":"Donna K. Finch"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079952","@type":"Researcher","foaf:name":[{"@value":"Andrew J. Fisher"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079809","@type":"Researcher","foaf:name":[{"@value":"Alasdair Gaw"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079949","@type":"Researcher","foaf:name":[{"@value":"Alan J. Knox"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079955","@type":"Researcher","foaf:name":[{"@value":"Ruth J. Mayer"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079951","@type":"Researcher","foaf:name":[{"@value":"Michael Polkey"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097080066","@type":"Researcher","foaf:name":[{"@value":"Michael Salmon"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319097079953","@type":"Researcher","foaf:name":[{"@value":"David Singh"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00916749"}],"prism:publicationName":[{"@value":"Journal of Allergy and Clinical Immunology"}],"dc:publisher":[{"@value":"Elsevier BV"}],"prism:publicationDate":"2015-09","prism:volume":"136","prism:number":"3","prism:startingPage":"769","prism:endingPage":"780"},"reviewed":"false","dc:rights":["https://www.elsevier.com/tdm/userlicense/1.0/","https://www.elsevier.com/legal/tdmrep-license","http://creativecommons.org/licenses/by/4.0/"],"url":[{"@id":"https://api.elsevier.com/content/article/PII:S0091674915002651?httpAccept=text/plain"},{"@id":"https://api.elsevier.com/content/article/PII:S0091674915002651?httpAccept=text/xml"}],"createdAt":"2015-04-06","modifiedAt":"2025-09-25","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360285705170120320","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Increased sorbitol levels in the hypertrophic ligamentum flavum of diabetic patients with lumbar spinal canal stenosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360584340692765696","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Supersulphides provide airway protection in viral and chronic lung diseases"}]},{"@id":"https://cir.nii.ac.jp/crid/1390305411857532288","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effect of α- and δ-Tocotrienol on Human Airway Smooth Muscle Cells~Tocotrienols as Potential Candidates for the Treatment of Airway Remodeling in Asthma"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1016/j.jaci.2015.01.046"},{"@type":"CROSSREF","@value":"10.1002/jor.23302_references_DOI_U1HHRB1pCp7hlAEKmZarXhguaOn"},{"@type":"CROSSREF","@value":"10.1038/s41467-023-40182-4_references_DOI_U1HHRB1pCp7hlAEKmZarXhguaOn"},{"@type":"CROSSREF","@value":"10.3177/jnsv.71.300_references_DOI_U1HHRB1pCp7hlAEKmZarXhguaOn"}]}