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- Valentina Vicennati
- University Alma Mater Studiorum, Bologna, Italy
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- Andrea Repaci
- University Alma Mater Studiorum, Bologna, Italy
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- Guido di Dalmazi
- University Alma Mater Studiorum, Bologna, Italy
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- Eleonora Rinaldi
- University Alma Mater Studiorum, Bologna, Italy
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- Rita Golfieri
- University Alma Mater Studiorum, Bologna, Italy
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- Emanuela Giampalma
- University Alma Mater Studiorum, Bologna, Italy
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- Francesco Minni
- University Alma Mater Studiorum, Bologna, Italy
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- Nicola Marrano
- University Alma Mater Studiorum, Bologna, Italy
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- Donatella Santini
- University Alma Mater Studiorum, Bologna, Italy
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- Renato Pasquali
- University Alma Mater Studiorum, Bologna, Italy
説明
<jats:p> A 70-year-old woman was referred to the authors’ unit following hospitalization for cardiac failure, high urinary free cortisol concentrations and severe hypokaliemia. A computed tomography scan of the abdomen showed an adrenal adenoma. The 24-hour urinary free cortisol values were high and plasma cortisol levels failed to suppress following 1 mg dexamethasone test. Aldosterone to plasma renin activity ratio was also pathologic, confirmed by saline load. She showed no symptoms of glucocorticoid excess. She was diagnosed with combined primary hyperaldosteronism and Cushing’s syndrome. Cases of adrenal incidentalomas co-secreting cortisol and aldosterone are rare; they should be addressed in patients undergoing adrenal surgery for Conn’s syndrome to avoid adrenal insufficiency after removal of the tumor. </jats:p>
収録刊行物
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- International Journal of Surgical Pathology
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International Journal of Surgical Pathology 20 (3), 316-319, 2011-11-08
SAGE Publications