{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670319758941568.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/ajoc.201300097"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fajoc.201300097"}},{"identifier":{"@type":"URI","@value":"https://aces.onlinelibrary.wiley.com/doi/pdf/10.1002/ajoc.201300097"}}],"dc:title":[{"@value":"Recent Advances in the Use of Chiral Brønsted Acids as Cooperative Catalysts in Cascade and Multicomponent Reactions"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>Abstract</jats:title><jats:p>In recent years, chiral Brønsted acid catalysts have been widely used in numerous enantioselective carbon–carbon and carbon–heteroatom bond‐forming reactions. Cascade/domino reactions and multicomponent reactions provide highly efficient, operationally simple, and atom‐economical approaches to the synthesis of polyfunctional complex molecules that are useful for modern organic chemistry and drug discovery. The control of stereoselectivity in these reactions remains a great challenge. Chiral Brønsted acid catalysts were rationally introduced as bifunctional catalysts to achieve synergetic catalysis for well‐controlled stereoselectivity. The synergy between chiral Brønsted acid catalysts and other compatible catalysts provides additional avenues for the discovery of novel organic transformations and improves reaction selectivity as well. In this Focus Review, recent advances in the uses of chiral Brønsted acids as cooperative catalysts in asymmetric cascade/multicomponent reactions are summarized.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670319758941570","@type":"Researcher","foaf:name":[{"@value":"Fengping Lv"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319758941568","@type":"Researcher","foaf:name":[{"@value":"Shunying Liu"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670319758941569","@type":"Researcher","foaf:name":[{"@value":"Wenhao Hu"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"21935807"},{"@type":"EISSN","@value":"21935815"}],"prism:publicationName":[{"@value":"Asian Journal of Organic Chemistry"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2013-08","prism:volume":"2","prism:number":"10","prism:startingPage":"824","prism:endingPage":"836"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fajoc.201300097"},{"@id":"https://aces.onlinelibrary.wiley.com/doi/pdf/10.1002/ajoc.201300097"}],"createdAt":"2013-08-01","modifiedAt":"2025-10-07","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360009142581478144","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Design of Phosphinic Acid Catalysts with the Closest Stereogenicity at the α-Position: Synthesis and Application of α-Stereogenic Perfluoroalkyl Phosphinic Acid Catalysts"}]},{"@id":"https://cir.nii.ac.jp/crid/1360283691155098624","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Silica gel-supported Brønsted acid: reactions in the column system"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285707504618624","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Desymmetrization of acid anhydride with asymmetric esterification catalyzed by chiral phosphoric acid"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285708118506624","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"One-Pot Catalysis Using a Chiral Iridium Complex/Brønsted Base: Catalytic Asymmetric Synthesis of Catalponol"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567183167217536","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Mechanistic Studies of Highly Enantio- and Diastereoselective Aza-Petasis–Ferrier Rearrangement Catalyzed by Chiral Phosphoric Acid"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848654926722688","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"3‐Mono‐Substituted BINOL Phosphoric Acids as Effective Organocatalysts in Direct Enantioselective Friedel–Crafts‐Type Alkylation of N‐Unprotected α‐Ketiminoester"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/ajoc.201300097"},{"@type":"CROSSREF","@value":"10.1021/acs.orglett.9b01131_references_DOI_3Rad4mQiD5rbTZ88J29bXhVHQNf"},{"@type":"CROSSREF","@value":"10.1021/acs.orglett.5b02480_references_DOI_3Rad4mQiD5rbTZ88J29bXhVHQNf"},{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2016.07.093_references_DOI_3Rad4mQiD5rbTZ88J29bXhVHQNf"},{"@type":"CROSSREF","@value":"10.1002/chem.201804078_references_DOI_3Rad4mQiD5rbTZ88J29bXhVHQNf"},{"@type":"CROSSREF","@value":"10.1016/j.tetlet.2014.12.046_references_DOI_3Rad4mQiD5rbTZ88J29bXhVHQNf"},{"@type":"CROSSREF","@value":"10.1021/ja5017206_references_DOI_3Rad4mQiD5rbTZ88J29bXhVHQNf"}]}