Mechanisms of COPII vesicle formation and protein sorting
書誌事項
- 公開日
- 2007-02-14
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1016/j.febslet.2007.01.091
- 公開者
- Wiley
この論文をさがす
説明
<jats:p>The evolutionarily conserved coat protein complex II (COPII) generates transport vesicles that mediate protein transport from the endoplasmic reticulum (ER). COPII coat is responsible for direct capture of cargo proteins and for the physical deformation of the ER membrane that drives the COPII vesicle formation. In addition to coat proteins, recent data have indicated that the Ras‐like small GTPase Sar1 plays multiple roles, such as COPII coat recruitment, cargo sorting, and completion of the final fission. In the present review, we summarize current knowledge of COPII‐mediated vesicle formation from the ER, as well as highlighting non‐canonical roles of COPII components.</jats:p>
収録刊行物
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- FEBS Letters
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FEBS Letters 581 (11), 2076-2082, 2007-02-14
Wiley
