{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670320264570112.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1101/gr.341802"}},{"identifier":{"@type":"URI","@value":"https://syndication.highwire.org/content/doi/10.1101/gr.341802"}}],"dc:title":[{"@value":"Evidence That Plant-Like Genes in\n                    <i>Chlamydia</i>\n                    Species Reflect an Ancestral Relationship between Chlamydiaceae, Cyanobacteria, and the Chloroplast"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>\n                    An unusually high proportion of proteins encoded in\n                    <jats:italic>Chlamydia</jats:italic>\n                    genomes are most similar to plant proteins, leading to proposals that a\n                    <jats:italic>Chlamydia</jats:italic>\n                    ancestor obtained genes from a plant or plant-like host organism by horizontal gene transfer. However, during an analysis of bacterial–eukaryotic protein similarities, we found that the vast majority of plant-like sequences in\n                    <jats:italic>Chlamydia</jats:italic>\n                    are most similar to plant proteins that are targeted to the chloroplast, an organelle derived from a cyanobacterium. We present further evidence suggesting that plant-like genes in\n                    <jats:italic>Chlamydia</jats:italic>\n                    , and other Chlamydiaceae, are likely a reflection of an unappreciated evolutionary relationship between the Chlamydiaceae and the cyanobacteria-chloroplast lineage. Further analyses of bacterial and eukaryotic genomes indicates the importance of evaluating organellar ancestry of eukaryotic proteins when identifying bacteria-eukaryote homologs or horizontal gene transfer and supports the proposal that Chlamydiaceae, which are obligate intracellular bacterial pathogens of animals, are not likely exchanging DNA with their hosts.\n                  </jats:p>\n                  <jats:p>\n                    [Supplementary Material is available online at\n                    <jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"uri\" xlink:href=\"http://www.genome.org\" xlink:type=\"simple\">http://www.genome.org</jats:ext-link>\n                    and at\n                    <jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" ext-link-type=\"uri\" xlink:href=\"http://www.pathogenomics.bc.ca/BAE-watch.html\" xlink:type=\"simple\">http://www.pathogenomics.bc.ca/BAE-watch.html</jats:ext-link>\n                    .]\n                  </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670320264570114","@type":"Researcher","foaf:name":[{"@value":"Fiona S.L. Brinkman"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570122","@type":"Researcher","foaf:name":[{"@value":"Jeffrey L. Blanchard"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570118","@type":"Researcher","foaf:name":[{"@value":"Artem Cherkasov"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570112","@type":"Researcher","foaf:name":[{"@value":"Yossef Av-Gay"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570240","@type":"Researcher","foaf:name":[{"@value":"Robert C. Brunham"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570119","@type":"Researcher","foaf:name":[{"@value":"Rachel C. Fernandez"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570121","@type":"Researcher","foaf:name":[{"@value":"B. Brett Finlay"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570115","@type":"Researcher","foaf:name":[{"@value":"Sarah P. Otto"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570113","@type":"Researcher","foaf:name":[{"@value":"B.F. Francis Ouellette"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570117","@type":"Researcher","foaf:name":[{"@value":"Patrick J. Keeling"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570116","@type":"Researcher","foaf:name":[{"@value":"Ann M. Rose"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570120","@type":"Researcher","foaf:name":[{"@value":"Robert E.W. Hancock"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320264570123","@type":"Researcher","foaf:name":[{"@value":"Steven J.M. Jones"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"10889051"},{"@type":"EISSN","@value":"15495469"},{"@type":"PISSN","@value":"http://id.crossref.org/issn/10889051"}],"prism:publicationName":[{"@value":"Genome Research"}],"dc:publisher":[{"@value":"Cold Spring Harbor Laboratory"}],"prism:publicationDate":"2002-07-19","prism:volume":"12","prism:number":"8","prism:startingPage":"1159","prism:endingPage":"1167"},"reviewed":"false","url":[{"@id":"https://syndication.highwire.org/content/doi/10.1101/gr.341802"}],"createdAt":"2002-11-13","modifiedAt":"2021-11-18","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050001202661779584","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Evidence for lateral gene transfer (LGT) in the evolution of eubacteria-derived small GTPases in plant organelles"}]},{"@id":"https://cir.nii.ac.jp/crid/1360002217601665024","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A Cryptic Algal Group Unveiled: A Plastid Biosynthesis Pathway in the Oyster Parasite Perkinsus marinus"}]},{"@id":"https://cir.nii.ac.jp/crid/1363951794830382464","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The complete genome of\n            <i>Rhodococcus</i>\n            sp. RHA1 provides insights into a catabolic powerhouse"},{"@language":"en","@value":"The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse."}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1101/gr.341802"},{"@type":"CROSSREF","@value":"10.1093/molbev/msn064_references_DOI_Z4p7gVedkqs5smKUcbvMQrAc4Cf"},{"@type":"CROSSREF","@value":"10.3389/fpls.2014.00678_references_DOI_Z4p7gVedkqs5smKUcbvMQrAc4Cf"},{"@type":"CROSSREF","@value":"10.1073/pnas.0607048103_references_DOI_Z4p7gVedkqs5smKUcbvMQrAc4Cf"}]}