{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670320363271680.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1007/s12328-016-0654-7"}},{"identifier":{"@type":"URI","@value":"http://link.springer.com/content/pdf/10.1007/s12328-016-0654-7.pdf"}},{"identifier":{"@type":"URI","@value":"http://link.springer.com/article/10.1007/s12328-016-0654-7/fulltext.html"}},{"identifier":{"@type":"URI","@value":"http://link.springer.com/content/pdf/10.1007/s12328-016-0654-7"}},{"identifier":{"@type":"PMID","@value":"27259702"}}],"dc:title":[{"@value":"Intestinal-type gastric adenocarcinoma without Helicobacter pylori infection successfully treated with endoscopic submucosal dissection"}],"description":[{"notation":[{"@value":"A 67-year-old woman was admitted to our hospital for further examination and for treatment of gastric neoplasia located on the posterior wall of the antrum of the stomach, as revealed by screening esophagogastroduodenoscopy. The patient had no history of Helicobacter pylori (H. pylori) eradication. Her serum H. pylori antibody and urea breath test results were negative, histopathological findings revealed no H. pylori bacteria, and endoscopic findings revealed no chronic gastritis. We performed endoscopic submucosal dissection (ESD). Histological examination of the resected tissues revealed the tumor to be composed of a well-differentiated tubular adenocarcinoma with a tubular-type adenoma confined to the mucosa. This adenocarcinoma exhibited immunohistochemical expression of CD10, MUC2, and Cdx2, but not MUC5AC or MUC6. This is an extremely rare case of H. pylori infection-negative, intestinal-type, differentiated gastric adenocarcinoma revealed by detailed immunohistochemical examination that was treated with ESD. The patient has had no recurrence of adenocarcinoma after ESD."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670320363271685","@type":"Researcher","foaf:name":[{"@value":"Satoshi Kotani"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271686","@type":"Researcher","foaf:name":[{"@value":"Youichi Miyaoka"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271681","@type":"Researcher","foaf:name":[{"@value":"Aya Fujiwara"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271684","@type":"Researcher","foaf:name":[{"@value":"Kousuke Tsukano"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271682","@type":"Researcher","foaf:name":[{"@value":"Sayaka Ogawa"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271680","@type":"Researcher","foaf:name":[{"@value":"Satoshi Yamanouchi"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271683","@type":"Researcher","foaf:name":[{"@value":"Ryusaku Kusunoki"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271553","@type":"Researcher","foaf:name":[{"@value":"Hirofumi Fujishiro"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271552","@type":"Researcher","foaf:name":[{"@value":"Naruaki Kohge"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271555","@type":"Researcher","foaf:name":[{"@value":"Hideyuki Ohnuma"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320363271554","@type":"Researcher","foaf:name":[{"@value":"Yoshikazu Kinoshita"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"18657257"},{"@type":"EISSN","@value":"18657265"}],"prism:publicationName":[{"@value":"Clinical Journal of Gastroenterology"}],"dc:publisher":[{"@value":"Springer Science and Business Media LLC"}],"prism:publicationDate":"2016-06-03","prism:volume":"9","prism:number":"4","prism:startingPage":"228","prism:endingPage":"232"},"reviewed":"false","dc:rights":["http://www.springer.com/tdm"],"url":[{"@id":"http://link.springer.com/content/pdf/10.1007/s12328-016-0654-7.pdf"},{"@id":"http://link.springer.com/article/10.1007/s12328-016-0654-7/fulltext.html"},{"@id":"http://link.springer.com/content/pdf/10.1007/s12328-016-0654-7"}],"createdAt":"2016-06-03","modifiedAt":"2020-09-21","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Endoscopic%20Mucosal%20Resection","dc:title":"Endoscopic Mucosal Resection"},{"@id":"https://cir.nii.ac.jp/all?q=Helicobacter%20pylori","dc:title":"Helicobacter pylori"},{"@id":"https://cir.nii.ac.jp/all?q=Adenocarcinoma","dc:title":"Adenocarcinoma"},{"@id":"https://cir.nii.ac.jp/all?q=Middle%20Aged","dc:title":"Middle Aged"},{"@id":"https://cir.nii.ac.jp/all?q=Helicobacter%20Infections","dc:title":"Helicobacter Infections"},{"@id":"https://cir.nii.ac.jp/all?q=Stomach%20Neoplasms","dc:title":"Stomach Neoplasms"},{"@id":"https://cir.nii.ac.jp/all?q=Gastroscopy","dc:title":"Gastroscopy"},{"@id":"https://cir.nii.ac.jp/all?q=Humans","dc:title":"Humans"},{"@id":"https://cir.nii.ac.jp/all?q=Female","dc:title":"Female"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360294643786550272","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Intestinal-type gastric dysplasia in Helicobacter pylori-naïve patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1360588379382597888","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Gastric dysplastic lesions in <i>Helicobacter pylori</i>‐naïve stomach: Foveolar‐type adenoma and intestinal‐type dysplasia"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861704773513216","@type":"Article","resourceType":"学術雑誌論文(journal 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