Maternal depression during pregnancy and offspring depression in adulthood: Role of child maltreatment
書誌事項
- 公開日
- 2015-09
- 権利情報
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- http://creativecommons.org/licenses/by/3.0/
- DOI
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- 10.1192/bjp.bp.114.156620
- 公開者
- Royal College of Psychiatrists
この論文をさがす
説明
<jats:sec><jats:title>Background</jats:title><jats:p>Studies have shown that maternal depression during pregnancy predicts offspring depression in adolescence. Child maltreatment is also a risk factor for depression.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>To investigate (a) whether there is an association between offspring exposure to maternal depression in pregnancy and depression in early adulthood, and (b) whether offspring child maltreatment mediates this association.</jats:p></jats:sec><jats:sec><jats:title>Method</jats:title><jats:p>Prospectively collected data on maternal clinical depression in pregnancy, offspring child maltreatment and offspring adulthood (18–25 years) DSM-IV depression were analysed in 103 mother–offspring dyads of the South London Child Development Study.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Adult offspring exposed to maternal depression in pregnancy were 3.4 times more likely to have a DSM-IV depressive disorder, and 2.4 times more likely to have experienced child maltreatment, compared with non-exposed offspring. Path analysis revealed that offspring experience of child maltreatment mediated the association between exposure to maternal depression in pregnancy and depression in adulthood.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Maternal depression in pregnancy is a key vulnerability factor for offspring depression in early adulthood.</jats:p></jats:sec>
収録刊行物
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- British Journal of Psychiatry
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British Journal of Psychiatry 207 (3), 213-220, 2015-09
Royal College of Psychiatrists
