{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670320770444288.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1007/s00253-019-09629-x"}},{"identifier":{"@type":"URI","@value":"http://link.springer.com/article/10.1007/s00253-019-09629-x/fulltext.html"}},{"identifier":{"@type":"URI","@value":"http://link.springer.com/content/pdf/10.1007/s00253-019-09629-x.pdf"}},{"identifier":{"@type":"PMID","@value":"30680434"}}],"dc:title":[{"@value":"Bacteriophage-host arm race: an update on the mechanism of phage resistance in bacteria and revenge of the phage with the perspective for phage therapy"}],"description":[{"notation":[{"@value":"Due to a constant attack by phage, bacteria in the environment have evolved diverse mechanisms to defend themselves. Several reviews on phage resistance mechanisms have been published elsewhere. Thanks to the advancement of molecular techniques, several new phage resistance mechanisms were recently identified. For the practical phage therapy, the emergence of phage-resistant bacteria could be an obstacle. However, unlike antibiotic, phages could evolve a mechanism to counter-adapt against phage-resistant bacteria. In this review, we summarized the most recent studies of the phage-bacteria arm race with the perspective of future applications of phages as antimicrobial agents."}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670320770444288","@type":"Researcher","foaf:name":[{"@value":"Aa Haeruman Azam"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320770444289","@type":"Researcher","foaf:name":[{"@value":"Yasunori Tanji"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"01757598"},{"@type":"EISSN","@value":"14320614"}],"prism:publicationName":[{"@value":"Applied Microbiology and Biotechnology"}],"dc:publisher":[{"@value":"Springer Science and Business Media LLC"}],"prism:publicationDate":"2019-01-24","prism:volume":"103","prism:number":"5","prism:startingPage":"2121","prism:endingPage":"2131"},"reviewed":"false","dc:rights":["http://www.springer.com/tdm"],"url":[{"@id":"http://link.springer.com/article/10.1007/s00253-019-09629-x/fulltext.html"},{"@id":"http://link.springer.com/content/pdf/10.1007/s00253-019-09629-x.pdf"}],"createdAt":"2019-01-24","modifiedAt":"2020-01-23","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Bacteria","dc:title":"Bacteria"},{"@id":"https://cir.nii.ac.jp/all?q=Cell%20Membrane","dc:title":"Cell Membrane"},{"@id":"https://cir.nii.ac.jp/all?q=Repressor%20Proteins","dc:title":"Repressor Proteins"},{"@id":"https://cir.nii.ac.jp/all?q=Bacterial%20Proteins","dc:title":"Bacterial Proteins"},{"@id":"https://cir.nii.ac.jp/all?q=Bacteriophages","dc:title":"Bacteriophages"},{"@id":"https://cir.nii.ac.jp/all?q=RNA%20Interference","dc:title":"RNA Interference"},{"@id":"https://cir.nii.ac.jp/all?q=Phage%20Therapy","dc:title":"Phage Therapy"},{"@id":"https://cir.nii.ac.jp/all?q=CRISPR-Cas%20Systems","dc:title":"CRISPR-Cas Systems"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050018198818283264","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Biological properties of Staphylococcus virus ΦSA012 for phage therapy"}]},{"@id":"https://cir.nii.ac.jp/crid/1050571339784716928","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Use of Recombinant Endolysin to Improve Accuracy of Group B Streptococcus Tests"}]},{"@id":"https://cir.nii.ac.jp/crid/1360005515806446336","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Silviavirus phage ɸMR003 displays a broad host range against methicillin-resistant Staphylococcus aureus of human origin"}]},{"@id":"https://cir.nii.ac.jp/crid/1360287219302131456","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Bacteriophages in Natural and Artificial Environments"}]},{"@id":"https://cir.nii.ac.jp/crid/1360302865558803840","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Selective bacteriophages reduce the emergence of resistant bacteria in bacteriophage-antibiotic combination therapy"}]},{"@id":"https://cir.nii.ac.jp/crid/1360850316100556032","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Analysis host-recognition mechanism of staphylococcal kayvirus ɸSA039 reveals a novel strategy that protects Staphylococcus aureus against infection by Staphylococcus pseudintermedius Siphoviridae phages"}]},{"@id":"https://cir.nii.ac.jp/crid/1360857593755053440","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Bacteriophage Technology and Modern Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/2120307889490804224","@type":"OtherWorks","resourceType":"学術雑誌論文(journal article)","relationType":["isIdenticalTo"],"jpcoar:relatedTitle":[{"@value":"Bacteriophage-host arm race: an update on the mechanism of phage resistance in bacteria and revenge of the phage with the perspective for phage therapy"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1007/s00253-019-09629-x"},{"@type":"OPENAIRE","@value":"doi_dedup___::a6ff5492a4f95bf38fc1c1a78f950696"},{"@type":"IRDB","@value":"oai:irdb.nii.ac.jp:00897:0004124159_isIdenticalTo_DOI_S7ChW3kkA7KXqdIwMD3DPY30C4F"},{"@type":"CROSSREF","@value":"10.1007/s00253-019-10039-2_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.3390/pathogens8030100_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.1128/spectrum.00077-21_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.1128/spectrum.00427-23_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.1007/s00253-019-09940-7_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.3390/antibiotics10080999_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.1101/2023.01.22.525106_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.1038/s41598-022-25352-6_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"},{"@type":"CROSSREF","@value":"10.1101/632646_references_DOI_YpG3eDvj6rk1bSfJAJyhvVEpPSB"}]}