{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670320883654528.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1523/jneurosci.3302-16.2017"}},{"identifier":{"@type":"URI","@value":"https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.3302-16.2017"}}],"dc:title":[{"@value":"Development of the Cerebral Cortex across Adolescence: A Multisample Study of Inter-Related Longitudinal Changes in Cortical Volume, Surface Area, and Thickness"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Before we can assess and interpret how developmental changes in human brain structure relate to cognition, affect, and motivation, and how these processes are perturbed in clinical or at-risk populations, we must first precisely understand typical brain development and how changes in different structural components relate to each other. We conducted a multisample magnetic resonance imaging study to investigate the development of cortical volume, surface area, and thickness, as well as their inter-relationships, from late childhood to early adulthood (7–29 years) using four separate longitudinal samples including 388 participants and 854 total scans. These independent datasets were processed and quality-controlled using the same methods, but analyzed separately to study the replicability of the results across sample and image-acquisition characteristics. The results consistently showed widespread and regionally variable nonlinear decreases in cortical volume and thickness and comparably smaller steady decreases in surface area. Further, the dominant contributor to cortical volume reductions during adolescence was thinning. Finally, complex regional and topological patterns of associations between changes in surface area and thickness were observed. Positive relationships were seen in sulcal regions in prefrontal and temporal cortices, while negative relationships were seen mainly in gyral regions in more posterior cortices. Collectively, these results help resolve previous inconsistencies regarding the structural development of the cerebral cortex from childhood to adulthood, and provide novel insight into how changes in the different dimensions of the cortex in this period of life are inter-related.</jats:p>\n                  <jats:p>\n                    <jats:bold>SIGNIFICANCE STATEMENT</jats:bold>\n                    Different measures of brain anatomy develop differently across adolescence. Their precise trajectories and how they relate to each other throughout development are important to know if we are to fully understand both typical development and disorders involving aberrant brain development. However, our understanding of such trajectories and relationships is still incomplete. To provide accurate characterizations of how different measures of cortical structure develop, we performed an MRI investigation across four independent datasets. The most profound anatomical change in the cortex during adolescence was thinning, with the largest decreases observed in the parietal lobe. There were complex regional patterns of associations between changes in surface area and thickness, with positive relationships seen in sulcal regions in prefrontal and temporal cortices, and negative relationships seen mainly in gyral regions in more posterior cortices.\n                  </jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670320883654533","@type":"Researcher","foaf:name":[{"@value":"Christian K. Tamnes"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654536","@type":"Researcher","foaf:name":[{"@value":"Megan M. Herting"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654532","@type":"Researcher","foaf:name":[{"@value":"Anne-Lise Goddings"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654530","@type":"Researcher","foaf:name":[{"@value":"Rosa Meuwese"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654538","@type":"Researcher","foaf:name":[{"@value":"Sarah-Jayne Blakemore"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654531","@type":"Researcher","foaf:name":[{"@value":"Ronald E. Dahl"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654534","@type":"Researcher","foaf:name":[{"@value":"Berna Güroğlu"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654528","@type":"Researcher","foaf:name":[{"@value":"Armin Raznahan"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654529","@type":"Researcher","foaf:name":[{"@value":"Elizabeth R. Sowell"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654537","@type":"Researcher","foaf:name":[{"@value":"Eveline A. Crone"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320883654535","@type":"Researcher","foaf:name":[{"@value":"Kathryn L. Mills"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"02706474"},{"@type":"EISSN","@value":"15292401"}],"prism:publicationName":[{"@value":"The Journal of Neuroscience"}],"dc:publisher":[{"@value":"Society for Neuroscience"}],"prism:publicationDate":"2017-02-27","prism:volume":"37","prism:number":"12","prism:startingPage":"3402","prism:endingPage":"3412"},"reviewed":"false","dc:rights":["https://creativecommons.org/licenses/by-nc-sa/4.0/"],"url":[{"@id":"https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.3302-16.2017"}],"createdAt":"2017-02-27","modifiedAt":"2023-04-18","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360021390745842176","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Longitudinal change in mismatch negativity (MMN) but not in gamma-band auditory steady-state response (ASSR) is associated with psychological difficulties in adolescence"}]},{"@id":"https://cir.nii.ac.jp/crid/1360290617792443392","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Exposure to Radiofrequency Electromagnetic Field in the High-Frequency Band and Cognitive Function in Children and Adolescents: A Literature Review"}]},{"@id":"https://cir.nii.ac.jp/crid/1360290617792905344","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580232415418752","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Academic achievements and brain volume development in children and adolescents"}]},{"@id":"https://cir.nii.ac.jp/crid/1360849939247918848","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition"}]},{"@id":"https://cir.nii.ac.jp/crid/1390021692230368256","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Visualizing and Enhancing Somatosensory Functions"},{"@language":"ja","@value":"体性感覚機能の可視化と機能向上に向けたアプローチ"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1523/jneurosci.3302-16.2017"},{"@type":"CROSSREF","@value":"10.1093/cercor/bhad346_references_DOI_CWEOytPVxDyAZzlYmPXTCFeUHsP"},{"@type":"CROSSREF","@value":"10.3390/ijerph17249179_references_DOI_CWEOytPVxDyAZzlYmPXTCFeUHsP"},{"@type":"CROSSREF","@value":"10.1001/jamapsychiatry.2021.0638_references_DOI_CWEOytPVxDyAZzlYmPXTCFeUHsP"},{"@type":"CROSSREF","@value":"10.1093/texcom/tgac048_references_DOI_CWEOytPVxDyAZzlYmPXTCFeUHsP"},{"@type":"CROSSREF","@value":"10.2490/jjrmc.61.1192_references_DOI_CWEOytPVxDyAZzlYmPXTCFeUHsP"},{"@type":"CROSSREF","@value":"10.1001/jamapsychiatry.2019.3779_references_DOI_CWEOytPVxDyAZzlYmPXTCFeUHsP"}]}