{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670320915056128.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1002/wnan.1520"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fwnan.1520"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/wnan.1520"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/wnan.1520"}},{"identifier":{"@type":"URI","@value":"https://wires.onlinelibrary.wiley.com/doi/pdf/10.1002/wnan.1520"}}],"dc:title":[{"@value":"Double network hydrogel for tissue engineering"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>Double network (DN) hydrogels, a kind of promising soft and tough hydrogels, are produced by two unique contrasting networks with designed network entanglement burst into the field of materials science as versatile functional systems for a very broad range of applications. A part of the DN hydrogels is characterized by extraordinary mechanical properties providing efficient biocompatible and high strength for holding considerable promise in tissue engineering. Following DN hydrogels principles and consideration of biomedical applications, we provide an overall view of the present various DN hydrogels and look forward to the future of DN hydrogels for tissue engineering. In this review, the preparation methods, structure, properties, current situation, and challenges are mainly discussed for the purpose of tissue engineering.</jats:p><jats:p>This article is categorized under:<jats:list list-type=\"simple\"><jats:list-item><jats:p>Implantable Materials and Surgical Technologies > Nanomaterials and Implants</jats:p></jats:list-item><jats:list-item><jats:p>Implantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and Replacement</jats:p></jats:list-item></jats:list></jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383670320915056132","@type":"Researcher","foaf:name":[{"@value":"Zhipeng Gu"}],"jpcoar:affiliationName":[{"@value":"Department of Biomedical Engineering, School of Engineering Sun Yat‐sen University Guangzhou China"},{"@value":"State Key Laboratory of Polymer Materials Engineering Sichuan University Chengdu China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320915056131","@type":"Researcher","foaf:name":[{"@value":"Keqing Huang"}],"jpcoar:affiliationName":[{"@value":"Department of Biomedical Engineering, School of Engineering Sun Yat‐sen University Guangzhou China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320915056128","@type":"Researcher","foaf:name":[{"@value":"Yan Luo"}],"jpcoar:affiliationName":[{"@value":"Department of Chemical Engineering West Virginia University Morgantown West Virginia"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320915056257","@type":"Researcher","foaf:name":[{"@value":"Laibao Zhang"}],"jpcoar:affiliationName":[{"@value":"Cain Department of Chemical Engineering Louisiana State University Baton Rouge Louisiana"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320915056256","@type":"Researcher","foaf:name":[{"@value":"Tairong Kuang"}],"jpcoar:affiliationName":[{"@value":"The Key Laboratory of Polymer Processing Engineering of Ministry of Education South China University of Technology Guangzhou China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320915056129","@type":"Researcher","foaf:name":[{"@value":"Zhou Chen"}],"jpcoar:affiliationName":[{"@value":"School of Mechanical and Power Engineering Nanjing Tech University Nanjing China"}]},{"@id":"https://cir.nii.ac.jp/crid/1383670320915056130","@type":"Researcher","foaf:name":[{"@value":"Guochao Liao"}],"jpcoar:affiliationName":[{"@value":"International Institute for Translational Chinese Medicine Guangzhou University of Chinese Medicine Guangzhou China"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"19395116"},{"@type":"EISSN","@value":"19390041"}],"prism:publicationName":[{"@value":"WIREs Nanomedicine and Nanobiotechnology"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"2018-04-17","prism:volume":"10","prism:number":"6"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fwnan.1520"},{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1002/wnan.1520"},{"@id":"https://onlinelibrary.wiley.com/doi/full-xml/10.1002/wnan.1520"},{"@id":"https://wires.onlinelibrary.wiley.com/doi/pdf/10.1002/wnan.1520"}],"createdAt":"2018-04-17","modifiedAt":"2024-07-06","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050869456404891520","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Fabrication of Bioinspired Hydrogels : Challenges and Opportunities"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1002/wnan.1520"},{"@type":"CROSSREF","@value":"10.1021/acs.macromol.0c00238_references_DOI_STF3I142UVXPmKT1La2gJ8nwfYH"}]}