{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363670321221751808.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1056/nejmoa0801317"}},{"identifier":{"@type":"URI","@value":"http://www.nejm.org/doi/pdf/10.1056/NEJMoa0801317"}}],"dc:title":[{"@value":"Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1380004239491444101","@type":"Researcher","foaf:name":[{"@value":"Yusuf"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00284793"},{"@type":"EISSN","@value":"15334406"}],"prism:publicationName":[{"@value":"New England Journal of Medicine"}],"dc:publisher":[{"@value":"Massachusetts Medical Society"}],"prism:publicationDate":"2008-04-10","prism:volume":"358","prism:number":"15","prism:startingPage":"1547","prism:endingPage":"1559"},"reviewed":"false","url":[{"@id":"http://www.nejm.org/doi/pdf/10.1056/NEJMoa0801317"}],"createdAt":"2008-03-31","modifiedAt":"2025-01-29","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050013397240361344","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Calcium channel blocker in patients with chronic kidney disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1050285299951255936","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Randomized trial of an intensified, multifactorial intervention in patients with advanced‐stage diabetic kidney disease: Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT‐Japan)"},{"@value":"Randomized trial of an intensified, multifactorial intervention in patients with advanced-stage diabetic kidney disease: Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT-Japan)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360002218938524288","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A trial of telmisartan prevention of cardiovascular diseases (ATTEMPT-CVD): Biomarker study"}]},{"@id":"https://cir.nii.ac.jp/crid/1360002220677163520","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting  the HMGB1/RAGE Axis in Prevention and Acute  Treatment of Stroke"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004231497926784","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Angiotensin-(1-12): A Chymase-Mediated Cellular Angiotensin II Substrate"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004231561604096","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Causal Measures of the Treatment Effect Captured by Candidate Surrogate Endpoints"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004233086031104","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The association between blood pressure and cognitive function"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004233405725952","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Aliskiren in combination with valsartan exerts synergistic protective effects against ventricular remodeling after myocardial infarction in mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004233464822144","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers in hypertensive patients with myocardial infarction or heart failure: a systematic review and meta-analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004236340969216","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The Association between Hypertension and Dementia in the Elderly"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004236856689152","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Are the effects of blood pressure lowering treatment diminishing?: meta-regression analyses"}]},{"@id":"https://cir.nii.ac.jp/crid/1360004239491444096","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Clinical Neuroprotective Drugs for Treatment and Prevention of Stroke"}]},{"@id":"https://cir.nii.ac.jp/crid/1360005518347767040","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)"}]},{"@id":"https://cir.nii.ac.jp/crid/1360283692012378368","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Combined Angiotensin Inhibition in Diabetic Nephropathy"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285709874024960","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Comparison of telmisartan/amlodipine and telmisartan/hydrochlorothiazide in the treatment of Japanese patients with uncontrolled hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285711913859072","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"A Selective Peroxisome Proliferator-Activated Receptor-γ Modulator, Telmisartan, Binds to the Receptor in a Different Fashion from Thiazolidinediones"}]},{"@id":"https://cir.nii.ac.jp/crid/1360290617716328832","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Activation of the angiotensin II receptor promotes autophagy in renal proximal tubular cells and affords protection from ischemia/reperfusion injury"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565168684734976","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Hemodynamic and Hormonal Changes to Dual Renin–Angiotensin System Inhibition in Experimental Hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/1360565168945199744","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567181910255104","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Comparison of 5-Year Survival After Acute Myocardial Infarction Using Angiotensin-Converting Enzyme Inhibitor Versus Angiotensin II Receptor Blocker"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567181956990464","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Angiotensin II promotes pulmonary metastasis of melanoma through the activation of adhesion molecules in vascular endothelial cells"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567183616866304","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"An evolving story of angiotensin-II-forming pathways in rodents and humans"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567186389812864","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Novel Therapeutic Role for Dipeptidyl Peptidase III in the Treatment of Hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/1360567187463317376","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Direct Angiotensin II Type 2 Receptor Stimulation Ameliorates Insulin Resistance in Type 2 Diabetes Mice with PPARγ Activation"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846640299260160","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"It is Time to Reconsider the Cardiovascular Protection Afforded by RAAS Blockade - Overview of RAAS Systems"}]},{"@id":"https://cir.nii.ac.jp/crid/1360846642475781120","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Clinical impacts of additive use of olmesartan in hypertensive patients with chronic heart failure: the supplemental benefit of an angiotensin receptor blocker in hypertensive patients with stable heart failure using olmesartan (SUPPORT) trial"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848654995753856","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Beneficial Cardiometabolic Actions of Telmisartan Plus Amlodipine Therapy in Elderly Patients With Poorly Controlled Hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848656494797312","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Evidence-based practice guideline for the treatment for diabetes in Japan 2013"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848660677282432","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Aggressive Blood Pressure–Lowering Therapy Guided by Home Blood Pressure Monitoring Improves Target Organ Damage in Hypertensive Patients With Type 2 Diabetes/Prediabetes"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848661270599808","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848661361335552","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Angiotensin II Destabilizes Coronary Plaques in Watanabe Heritable Hyperlipidemic Rabbits"}]},{"@id":"https://cir.nii.ac.jp/crid/1360848664618371072","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy"}]},{"@id":"https://cir.nii.ac.jp/crid/1360861705568190080","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Is Blood Pressure Lowering in the Very Elderly With Previous Stroke Associated With a Higher Risk of Adverse Events?"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204432416000","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Rationale, Design and Baseline Characteristics of a Study to Evaluate Effects of Candesartan on Cardiovascular Events after Drug-eluting Stent Implantation in Patients with Ischemic Heart Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204432457344","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Blockade of Renin-Angiotensin System Attenuates Advanced Glycation End Products-Mediated Signaling Pathways"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204468957440","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Diagnosis and management of ischemic cardiomyopathy"},{"@language":"ja","@value":"Ischemic cardiomyopathyの概念と内科治療"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204628461568","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Evaluation for Antioxidant and Renoprotective Activity of Olmesartan Using Nephrectomy Rats"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204631594880","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Recent Advances in Drug-Induced Angioedema"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001204876206592","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The Prevalence of Japanese Outpatients with Hypertension Who Meet the Definition of Treatment Resistant Hypertension and Are Eligible for Enrolment in Clinical Trials of Endovascular Ultrasound Renal Denervation"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205096655232","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Blood Pressure Control in Patients with Chronic Kidney Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205102329856","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"How Is Combination Therapy With ACEI and ARB Applied in Patients With Acute Myocardial Infarction?"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205104118784","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effects of Valsartan, an Angiotensin II Receptor Blocker, on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction Who Receive an Angiotensin-Converting Enzyme Inhibitor"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205105654400","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Comparative Effects of Carvedilol vs Bisoprolol for Severe Congestive Heart Failure  - Special Reference to Atrial Fibrillation -"},{"@value":"Comparative effects of carvedilol vs. bisoprolol for severe congestive heart failure"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205108490112","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effect of Diuretic or Calcium-Channel Blocker Plus Angiotensin-Receptor Blocker on Diastolic Function in Hypertensive Patients"}]},{"@id":"https://cir.nii.ac.jp/crid/1390001205367420032","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"糖尿病とレニン・アンジオテンシン系抑制薬―レニン阻害薬を含めて―"},{"@language":"en","@value":"S10-5. Renin-Angiotensin Inhibitor against Diabetes Mellitus"}]},{"@id":"https://cir.nii.ac.jp/crid/1390003825203428480","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Clinical Outcome and Diverse Risk Factors for Different Therapeutic Target Locations of Peripheral Artery Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1390006740595297408","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Suspected Case of ACE-Inhibitor-Induced Laryngeal Angioedema"},{"@language":"ja","@value":"ACE阻害薬が原因と考えられた喉頭血管性浮腫例"},{"@language":"ja-Kana","@value":"ACE ソガイヤク ガ ゲンイン ト カンガエラレタ コウトウ ケッカンセイ フシュレイ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679409352960","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Plaque-Stabilizing Effect of Angiotensin-Converting Enzyme Inhibitor and/or Angiotensin Receptor Blocker in a Rabbit Plaque Model"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282679847915904","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"The Insulin Sparing Effect of Telmisartan in a Case of Type 2 Diabetes Mellitus Associated with Schizophrenia under Treatment of Risperidone"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680080070784","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Addition of Losartan to Angiotensin-Converting Enzyme Inhibitors Improves Insulin Resistance in Patients With Chronic Heart Failure Treated Without .BETA.-Blockers"},{"@value":"Addition of losartan to angiotensin-converting enzyme inhibitors improves insulin resistance in patients with chronic heart failure treated without β-blockers"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680155737984","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Renin–Angiotensin System, Hypertension, and Chronic Kidney Disease: Pharmacogenetic Implications"},{"@value":"Renin^|^ndash;Angiotensin System, Hypertension, and Chronic Kidney Disease: Pharmacogenetic Implications"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680203206016","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Effects of ARB or ACE-Inhibitor Administration on Plasma Levels of Aldosterone and Adiponectin in Hypertension"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680344878336","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"日本における動脈硬化性疾患の臨床試験　　意義，実施体制，デザインとエンドポイントに関する考察，結果の解釈　　４．ＪＩＫＥＩ　ＨＥＡＲＴ研究"},{"@language":"en","@value":"4. JIKEI-HEART Study"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680344879232","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"ja","@value":"日本における動脈硬化性疾患の臨床試験　　意義，実施体制，デザインとエンドポイントに関する考察，結果の解釈　　３．ＣＡＳＥ‐Ｊ研究"},{"@language":"en","@value":"3. CASE-J"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282680393494656","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Mechanisms of action of compounds that mimic beneficial effects of calorie restriction such as lifespan extension: Is taurine a promising candidate?"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681420196608","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"3) Heart Failure"},{"@language":"ja","@value":"3）心不全"},{"@value":"心不全"},{"@language":"ja-Kana","@value":"シンフゼン"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681420433536","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Hypertension"},{"@language":"ja","@value":"高血圧"},{"@value":"医学と医療の最前線 高血圧"},{"@language":"ja-Kana","@value":"イガク ト イリョウ ノ サイゼンセン コウケツアツ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390282681507250944","@type":"Article","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A case of angioedema of the tongue and floor of the mouth probably associated with an angiotensin II receptor blocker"},{"@language":"ja","@value":"アンギオテンシンII受容体拮抗薬によると考えられた舌・口底部の血管性浮腫の1例"},{"@value":"アンギオテンシン2受容体拮抗薬によると考えられた舌・口底部の血管性浮腫の1例"},{"@language":"ja-Kana","@value":"アンギオテンシン 2 ジュヨウタイ キッコウヤク ニ ヨル ト カンガエラレタ ゼツ コウテイブ ノ ケッカンセイ フシュ ノ 1レイ"}]},{"@id":"https://cir.nii.ac.jp/crid/1390570078121666816","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Changes in Drug Utilization After Publication of Clinical Trials and Drug-Related Scandals in Japan: An Interrupted Time Series Analysis, 2005–2017"}]},{"@id":"https://cir.nii.ac.jp/crid/1391131406293094272","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Diagnosis, Prevention, and Treatment of Cardiovascular Diseases in People With Type 2 Diabetes and Prediabetes　― A Consensus Statement Jointly From the Japanese Circulation Society and the Japan Diabetes Society ―"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1056/nejmoa0801317"},{"@type":"CROSSREF","@value":"10.1177/2047487315603221_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.3390/ijms140918899_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1007/s11906-014-0429-9_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1007/s13253-015-0215-4_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1017/s0959259810000444_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1038/hr.2011.136_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1038/s41440-018-0167-5_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1155/2012/320648_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1186/s40885-018-0101-9_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.2332/allergolint.12-rai-0493_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.3390/ijms13067739_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1254/jphs.12r03cr_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.3892/etm.2012.560_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1038/s41440-019-0284-9_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1253/circj.cj-09-0989_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1016/j.bcp.2018.04.012_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1272/jnms.79.111_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.2169/internalmedicine.49.3107_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.2169/naika.98.167_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.5794/jjoms.56.36_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.3999/jscpt.39.151_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.3999/jscpt.41.61s_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.5551/jat.14266_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1007/s10157-021-02153-1_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1253/circj.cj-20-0865_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1210/en.2008-0502_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.2188/jea.je20200181_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1248/bpb.32.2041_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1253/circj.cj-10-0395_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1016/j.amjcard.2014.03.055_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.2169/naika.98.2188_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.5631/jibirin.114.429_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1016/j.jphs.2020.12.001_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1161/hypertensionaha.112.201889_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1186/s12882-016-0337-0_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1042/cs20130400_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1161/hypertensionaha.116.07357_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1371/journal.pone.0048387_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1253/circj.cj-11-1102_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.5551/jat.3624_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1056/nejmc1315504_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.7793/jcoron.18.025_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1007/s13340-020-00471-5_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1007/s10557-011-6361-1_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1093/eurheartj/ehu504_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1002/clc.20855_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1007/s13340-015-0206-2_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1111/j.1751-7176.2012.00648.x_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1155/2012/159874_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1161/atvbaha.115.306871_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.7600/jpfsm.6.201_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1253/circj.cj-10-0251_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.5551/jat.13870_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.3999/jscpt.39.157_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1111/jdi.13339_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1161/jaha.121.022240_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.5551/jat.52647_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.2169/internalmedicine.9059-17_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1097/mbp.0000000000000172_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1253/circj.cj-15-0815_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"},{"@type":"CROSSREF","@value":"10.1536/ihj.50.501_references_DOI_PQpDsHQkt2mQNrIOjSr2tk90EZS"}]}