Inhibitor Discovery Targeting the Intermediate Structure of β-Amyloid Peptide on the Conformational Transition Pathway: Implications in the Aggregation Mechanism of β-Amyloid Peptide
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- Dongxiang Liu
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
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- Yechun Xu
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
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- Yu Feng
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
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- Hong Liu
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
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- Xu Shen
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
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- Kaixian Chen
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
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- Jianpeng Ma
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
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- Hualiang Jiang
- Center for Drug Design and Discovery, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, BCM-125, Houston, Texas 77030, and Department of Bioengineering, Rice University, Houston, Texas 77005
収録刊行物
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- Biochemistry
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Biochemistry 45 (36), 10963-10972, 2006-08-17
American Chemical Society (ACS)