{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1363951794802470272.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1128/iai.67.1.446-448.1999"}},{"identifier":{"@type":"URI","@value":"https://journals.asm.org/doi/pdf/10.1128/IAI.67.1.446-448.1999"}}],"dc:title":[{"@value":"γδ T-Cell Function in Pathogenesis of Cerebral Malaria in Mice Infected with<i>Plasmodium berghei</i>ANKA"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:title>ABSTRACT</jats:title><jats:p>Mice depleted of γδ T cells by monoclonal antibody treatment and infected with<jats:italic>Plasmodium berghei</jats:italic>ANKA did not develop cerebral malaria (CM). In striking contrast, δ<jats:sup>0/0</jats:sup>mice infected with<jats:italic>P. berghei</jats:italic>developed CM despite their γδ T-cell deficiency. γδ T cells appear to be essential for the pathogenesis of CM in mice having experienced normal ontogeny but not in mice genetically deprived of γδ T cells from the beginning of life.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1383951794802470273","@type":"Researcher","foaf:name":[{"@value":"D. M. Yañez"}],"jpcoar:affiliationName":[{"@value":"<!--label omitted: 1-->Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, Wisconsin"}]},{"@id":"https://cir.nii.ac.jp/crid/1383951794802470277","@type":"Researcher","foaf:name":[{"@value":"J. Batchelder"}],"jpcoar:affiliationName":[{"@value":"<!--label omitted: 1-->Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, Wisconsin"}]},{"@id":"https://cir.nii.ac.jp/crid/1383951794802470276","@type":"Researcher","foaf:name":[{"@value":"H. C. van der Heyde"}],"jpcoar:affiliationName":[{"@value":"<!--label omitted: 1-->Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, Wisconsin"}]},{"@id":"https://cir.nii.ac.jp/crid/1383951794802470274","@type":"Researcher","foaf:name":[{"@value":"D. D. Manning"}],"jpcoar:affiliationName":[{"@value":"<!--label omitted: 1-->Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, Wisconsin"}]},{"@id":"https://cir.nii.ac.jp/crid/1383951794802470275","@type":"Researcher","foaf:name":[{"@value":"W. P. Weidanz"}],"jpcoar:affiliationName":[{"@value":"<!--label omitted: 1-->Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, Wisconsin"}]}],"contributor":[{"@id":"https://cir.nii.ac.jp/crid/1383951794802470272","@type":"Researcher","foaf:name":[{"@value":"S. H. E. Kaufmann"}],"role":"editor"}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"00199567"},{"@type":"EISSN","@value":"10985522"}],"prism:publicationName":[{"@value":"Infection and Immunity"}],"dc:publisher":[{"@value":"American Society for Microbiology"}],"prism:publicationDate":"1999-01","prism:volume":"67","prism:number":"1","prism:startingPage":"446","prism:endingPage":"448"},"reviewed":"false","dc:rights":["https://journals.asm.org/non-commercial-tdm-license"],"url":[{"@id":"https://journals.asm.org/doi/pdf/10.1128/IAI.67.1.446-448.1999"}],"createdAt":"2019-12-31","modifiedAt":"2023-09-24","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1050301640292279680","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"γδ T cell-mediated activation of cDC1 orchestrates CD4+ Th1 cell priming in malaria"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580229831439744","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"γδ T‐cell–mediated immune responses to malaria"}]},{"@id":"https://cir.nii.ac.jp/crid/1360580232183599232","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Host immunity to Plasmodium infection: Contribution of Plasmodium berghei to our understanding of T cell-related immune response to blood-stage malaria"}]},{"@id":"https://cir.nii.ac.jp/crid/2050870367067416832","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Upper gastrointestinal pathophysiology due to mouse malaria Plasmodium berghei ANKA infection"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1128/iai.67.1.446-448.1999"},{"@type":"CROSSREF","@value":"10.3389/fimmu.2024.1426316_references_DOI_2HsjNUAtP9Oy7QyCsYmljnsO6Pz"},{"@type":"CROSSREF","@value":"10.1111/1348-0421.13059_references_DOI_2HsjNUAtP9Oy7QyCsYmljnsO6Pz"},{"@type":"CROSSREF","@value":"10.1016/j.parint.2022.102646_references_DOI_2HsjNUAtP9Oy7QyCsYmljnsO6Pz"},{"@type":"CROSSREF","@value":"10.1186/s41182-019-0146-9_references_DOI_2HsjNUAtP9Oy7QyCsYmljnsO6Pz"}]}