{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1364233268506497152.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.1046/j.1365-2559.1996.d01-515.x"}},{"identifier":{"@type":"URI","@value":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2559.1996.d01-515.x"}},{"identifier":{"@type":"URI","@value":"https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2559.1996.d01-515.x"}},{"identifier":{"@type":"NAID","@value":"30014691298"}}],"dc:title":[{"@value":"<b>T‐cell lymphoma in Hashimoto’s thyroiditis</b>"}],"description":[{"type":"abstract","notation":[{"@value":"<jats:p>An elderly Caucasian woman with a 2‐year‐history of hypothyroidism, treated with thyroxine, presented with a rapidly growing mass in the thyroid. The morphological and immunological features of this thyroid tumour were those of a peripheral T‐cell lymphoma with an immunophenotype commonly associated with HTLV‐1 positive‐adult T‐cell leukaemia/lymphoma, although serology for HTLV1 antibody was negative. Monoclonal gene rearrangements were demonstrated with T‐cell receptor beta‐ and gamma‐specific primers. There are several interesting features in this case (i): although primary B‐cell lymphomas (MALT‐associated lymphomas) of thyroid are a well‐recognized sequel to thyroiditis, primary T‐cell lymphomas are rare, even in areas of the world where adult T‐cell lymphomas predominate; (ii) the tumour showed the typical immunophenotype of an HTLV‐1 positive T‐cell lymphoma but the patient is English, has not visited endemic areas, and is serologically negative for HTLV–1; (iii) the residual thyroid gland showed a florid lymphocytic thyroiditis with Hu¨rthle cell change, typical of Hashimoto’s thyroiditis; (iv) unlike other reports of thyroid T‐cell lymphoma, which have presented with stage III‐IV disease, this tumour presented in the favourable clinical stage of IE.</jats:p>"}]}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1384233268506497156","@type":"Researcher","foaf:name":[{"@value":"Z.H. ABDUL‐RAHMAN"}]},{"@id":"https://cir.nii.ac.jp/crid/1384233268506497158","@type":"Researcher","foaf:name":[{"@value":"H.J. GOGAS"}]},{"@id":"https://cir.nii.ac.jp/crid/1384233268506497152","@type":"Researcher","foaf:name":[{"@value":"J.A. TOOZE"}]},{"@id":"https://cir.nii.ac.jp/crid/1384233268506497154","@type":"Researcher","foaf:name":[{"@value":"B. ANDERSON"}]},{"@id":"https://cir.nii.ac.jp/crid/1384233268506497157","@type":"Researcher","foaf:name":[{"@value":"J. MANSI"}]},{"@id":"https://cir.nii.ac.jp/crid/1384233268506497153","@type":"Researcher","foaf:name":[{"@value":"N.P. SACKS"}]},{"@id":"https://cir.nii.ac.jp/crid/1384233268506497155","@type":"Researcher","foaf:name":[{"@value":"C.J. FINLAYSON"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"03090167"},{"@type":"EISSN","@value":"13652559"}],"prism:publicationName":[{"@value":"Histopathology"}],"dc:publisher":[{"@value":"Wiley"}],"prism:publicationDate":"1996-11","prism:volume":"29","prism:number":"5","prism:startingPage":"455","prism:endingPage":"459"},"reviewed":"false","dc:rights":["http://onlinelibrary.wiley.com/termsAndConditions#vor"],"url":[{"@id":"https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1365-2559.1996.d01-515.x"},{"@id":"https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1365-2559.1996.d01-515.x"}],"createdAt":"2003-11-02","modifiedAt":"2023-09-11","relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360004235482718720","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Primary peripheral <scp>T</scp>‐cell lymphoma, not otherwise specified of the thyroid with autoimmune thyroiditis"}]},{"@id":"https://cir.nii.ac.jp/crid/1360285711766327552","@type":"Article","resourceType":"学術雑誌論文(journal article)","relationType":["isReferencedBy"],"jpcoar:relatedTitle":[{"@value":"Problems of primary T-cell lymphoma of the thyroid gland -A case report"}]},{"@id":"https://cir.nii.ac.jp/crid/1570572699507945088","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"γδ T-cell lymphma a clinicopathologi study of 6 cases including extrahepatosplenic type"}]},{"@id":"https://cir.nii.ac.jp/crid/1571417125254976512","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"A Case of Non-Hodgkin's Lymphoma Following Long-Term Corticosteroid Therapy for Addison's Disease"}]},{"@id":"https://cir.nii.ac.jp/crid/1573387450307633024","@type":"Article","relationType":["isCitedBy"],"jpcoar:relatedTitle":[{"@language":"en","@value":"Malignant T -cell lymphoma of the thyroid gland associated with Hashimoto's thyroiditis"}]}],"dataSourceIdentifier":[{"@type":"CROSSREF","@value":"10.1046/j.1365-2559.1996.d01-515.x"},{"@type":"CIA","@value":"30014691298"},{"@type":"CROSSREF","@value":"10.1111/bjh.12255_references_DOI_aPs7a68zpyTkoN9p3kl5cfFriBq"},{"@type":"CROSSREF","@value":"10.1186/1477-7819-10-58_references_DOI_aPs7a68zpyTkoN9p3kl5cfFriBq"}]}