CLINICAL EVALUATION OF ENDOSCOPIC INJECTION SCLEROTHERAPY (EIS) IN PATIENTS WITH LIVER CIRRHOSIS : A RETROSPECTIVE ANALYSIS IN COMPARISON WITH PATIENTS NOT UNDERGOING EIS

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  • 肝硬変症例における内視鏡的食道静脈瘤硬化療法の臨床的有用性―硬化療法未施行例との予後の比較を中心に―

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Endoscopic injection sclerotherapy (EIS) in cirrhotic patients was evaluated in compar-ison with patients not undergoing EIS. The subjects were 109 cases with EIS (EIS cases) and 50 cases without EIS (non-EIS cases) of liver cirrhosis (LC) with or without hepatocel-lular carcinoma (HCC) in the same period. All cases had the stage III esophageal varices. The results were as follows: 1) Urgent hemostatic rate in EIS cases was significantly higher than that in non-EIS cases, especially in cases with HCC. 2) In the follow-up period, the rate of bleeding and the death rate for bleeding after EIS in EIS cases was significantly lower than that in non-EIS cases, especially in LC cases without HCC. 3) The cumulative survival probability in elective EIS cases was significantly higher than that in non-EIS cases who had episodes of variceal bleeding. 4) The cumulative survival probability in prophylactic EIS cases was significantly higher than that in non-EIS cases who had no episode of wariceal bleeding, especially in cases that had good hepatic reserve (Child'A or B) without HCC.<BR> In conclusion, urgent and elective EIS made a good prognosis of LC with stage III esophageal varices. Prophylactic EIS is also necessary in cases of LC with stage III esophageal varices.

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