{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001204281115264.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.3719/weed.35.44"}},{"identifier":{"@type":"NAID","@value":"130003811060"}}],"dc:title":[{"@language":"en","@value":"Plant growth inhibitory activities of iridoidglucosides."},{"@value":"イリドイド配糖体類の植物生長抑制作用"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"The mode of action and structure-activity relationship of iridoidglucosides were examined.<br>1) Among the tested iridoidglucosides, asperuloside, geniposidic acid, geniposide and aucubin were isolated from higher plants, and genipin and deacetyl asperulosidic acid methyl ester were derived from the isolated glucosides (Fig. 1).<br>2) The plant growth inhibitory activities of the iridoidglucosides were stronger in the case of radicle elongation compared with the growth of the shoots. The inhibitory effects of the iridoidglucosides were stronger in rice seedlings than in lettuce seedlings (Fig. 2 and 3).<br>3) The inhibitory activities of paederosidic acid, geniposidic acid, aucubin and catalpol, which have a -OH group at the 6-position and/or -COOH group at the 4-position were reduced compared with those of asperuloside which has a lactone ring. On the other hand, deacetyl asperulosidic acid methyl ester and gardenoside, which have a -COOCH<sub>3</sub> group at the 4-position were found to be inactive at several dose levels or which other glucosides inhibited effectively the growth of seedlings of lettuce and rice (Fig. 2 and 3).<br>4) The glucosides also showed a strong growth inhibitory activity against catchweed seedlings, which the inhibitory activity of asperuloside accumulated at high concentrations in the catchweed tissues was markedly reduced (Table 1).<br>5) An aglycone, genipin derived from geniposide showed a strong inhibitory activity on growth and germination compared with the glucosides (Fig. 2, 3 and 4).<br>6) Inactive, deacetyl asperulosidic acid methyl ester was not affected by enzymatic hydrolysis with β-glucosidase. Based on these data, it appears that the inhibitory action of iridoidglucosides occurs after conversion into aglycone by hydrolysis <i>in vivo</i>."},{"@value":"イリドイド配糖体類の植物生理活性の作用機構ならびに構造-活性相関について検討した。<br>1) 供試配糖体のうち asperuloside, geniposidic acid, geniposide および aucubin は植物体より単離し, また genipin と deacetyl asperulosidic acid methyl ester は単離した配糖体より誘導した (Fig. 1)。<br>2) イリドイド配糖体による生長阻害は, 茎葉部に比べて根部で著しく強く, またその阻害はレタスに比べてイネで著しかった (Fig. 2, 3)。<br>3) 前報<sup>6)</sup>と合わせて考察すると, 供試イリドイド配糖体のうちでラクトン環が消失し, 6位炭素に水酸基, 4位炭素にカルボキシル基を配する成分は, ラクトン環を有する asperuloside に比較してその活性は低下した。 しかし6位炭素の水酸基が消失する場合は, かなり強い活性を維持した (Fig. 2, 3)。<br>4) Deacetyl asperulosidic acid methyl ester や gardenoside など4位炭素にカルボン酸メチルを配し, 6位又は8位炭素に水酸基を有する配糖体の根部伸長阻害は著しく低下した (Fig. 2, 3)。<br>5) 10<sup>-5</sup>～10<sup>-6</sup>mol濃度の配糖体を処理した幼根長の伸長は促進され, その傾向はレタスに比較してイネで顕著で, deacetyl asperulosidic methyl ester では180%以上もの促進を示した (Fig. 2, 3)。<br>6) Geniposide をβ-glucosidase で非糖体とした genipin は, 配糖体に比べてその生長阻害程度は強く, またレタス種子発芽にも阻害を示した (Fig. 2～4)。<br>7) ヤエムグラ幼苗に対する3種配糖体と genipin の生長阻害は1.2×10<sup>-3</sup>molでも認められたが, asperuloside の活性は著しく低かった (Table 1)。<br>8) 生長阻害活性を示さない deacetyl asperulosidic acid methyl ester はβ-glucosidase に対して加水分解を受けず, glucose を遊離しなかった。従ってイリドイド配糖体類の生長阻害作用は, 生体内でのβ-glucosidase による非糖体化の結果発現するものと推察した。"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1030566608325341705","@type":"Researcher","personIdentifier":[{"@type":"KAKEN_RESEARCHERS","@value":"10088198"},{"@type":"NRID","@value":"1000010088198"},{"@type":"NRID","@value":"9000004182716"},{"@type":"NRID","@value":"9000364936468"},{"@type":"NRID","@value":"9000021919442"},{"@type":"NRID","@value":"9000254836503"},{"@type":"NRID","@value":"9000021870119"},{"@type":"NRID","@value":"9000021879967"},{"@type":"NRID","@value":"9000254836507"},{"@type":"NRID","@value":"9000015278430"},{"@type":"NRID","@value":"9000254335549"},{"@type":"NRID","@value":"9000004248986"},{"@type":"NRID","@value":"9000364936427"},{"@type":"NRID","@value":"9000364762971"},{"@type":"NRID","@value":"9000364763141"},{"@type":"RESEARCHMAP","@value":"https://researchmap.jp/read0034030"}],"foaf:name":[{"@language":"en","@value":"KOMAI Koichiro"},{"@language":"ja","@value":"駒井 功一郎"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Agriculture, Kinki University"},{"@language":"ja","@value":"近畿大学農学部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204281115266","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254335961"}],"foaf:name":[{"@language":"en","@value":"TUJII Ikuo"},{"@language":"ja","@value":"辻井 郁雄"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Agriculture, Kinki University"},{"@language":"ja","@value":"近畿大学農学部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204281115267","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254335962"}],"foaf:name":[{"@language":"en","@value":"MIURA Makoto"},{"@language":"ja","@value":"三浦 睦"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"近畿大学農学部"},{"@language":"en","@value":"Faculty of Agriculture, Kinki University"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204281115265","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254335960"}],"foaf:name":[{"@language":"en","@value":"NAKASUGI Toru"},{"@language":"ja","@value":"中杉 徹"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Agriculture, Kinki University"},{"@language":"ja","@value":"近畿大学農学部"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204281115264","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000254335963"}],"foaf:name":[{"@language":"en","@value":"HAMADA Masayuki"},{"@language":"ja","@value":"浜田 昌之"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Faculty of Agriculture, Kinki University"},{"@language":"ja","@value":"近畿大学農学部"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"0372798X"},{"@type":"EISSN","@value":"18824757"},{"@type":"CODEN","@value":"ZASKAN"}],"prism:publicationName":[{"@language":"ja","@value":"雑草研究"},{"@language":"en","@value":"Journal of Weed Science and Technology"},{"@language":"en","@value":"J. Weed Sci. Tech."},{"@language":"en","@value":"Zasso Kenkyu"},{"@language":"ja","@value":"雑草研究"},{"@language":"en","@value":"J. Weed Sci. Tech"}],"dc:publisher":[{"@language":"en","@value":"The Weed Science Society of Japan"},{"@language":"ja","@value":"日本雑草学会"}],"prism:publicationDate":"1990","prism:volume":"35","prism:number":"1","prism:startingPage":"44","prism:endingPage":"52"},"reviewed":"false","availableAt":"1990","dataSourceIdentifier":[{"@type":"JALC","@value":"oai:japanlinkcenter.org:0000404904"},{"@type":"CROSSREF","@value":"10.3719/weed.35.44"},{"@type":"CIA","@value":"130003811060"}]}