{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001204301651200.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.2336/nishinihonhifu.40.629"}},{"identifier":{"@type":"NDL_BIB_ID","@value":"1958432"}},{"identifier":{"@type":"URI","@value":"http://id.ndl.go.jp/bib/1958432"}},{"identifier":{"@type":"URI","@value":"https://ndlsearch.ndl.go.jp/books/R000000004-I1958432"}},{"identifier":{"@type":"NAID","@value":"130004472476"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/1979102778"}}],"dc:title":[{"@language":"en","@value":"Overlapping Syndrome with Angio-Immunoblastic Lymphadenopathy (Frizzera)"},{"@language":"ja","@value":"Angio-Immunoblastic Lymphadenopathy(Frizzera)様のリンパ節所見を呈したOverlap症候群"},{"@value":"Angio-Immunoblastic Lymphadenopathy(Frizzera)様のリンパ節所見を呈したOverlap症候群--とくにImmunoblastic Lymphadenopathy(Lukes),Angio-Immunoblastic Lymphadenopathy,Immunodysplasia Syndrome(畔柳)との異同について"},{"@language":"ja-Kana","@value":"Angio Immunoblastic Lymphadenopathy Fri"}],"dcterms:alternative":[{"@language":"en","@value":"—With Special Reference to Relationship of Immunoblastic Lymphadenopathy (Lukes), Angio-Immunoblastic Lymphadenopathy and Immunodysplasia Syndrome (Kuroyanagi)—"},{"@language":"ja","@value":"—とくにImmunoblastic Lymphadenopathy(Lukes), Angio-Immunoblastic Lymphadenopathy, Immunodysplasia Syndrome(畔柳)との異同について—"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"A 28-year-old woman with angio-immunoblastic lymphadenopathy and overlapping syndrome was reported. Her condition was started with fever and pruritic erythema following oral administration of antipyretics. One month later muscle tenderness, weakness of the lower extremities, arthralgia and acrosclerosis developed. Those symptoms were persistent for two years despite systemic administration of corticosteroid. In May 1976, she was admitted to our clinic for Raynaud’s phenomenon, acrosclerosis, pain in the left chest and fever. Physical examination on admission showed hepatosplenomegaly, systemic lymphadenopathy, retention of pleural fluid and oral aphthae. A lymphnode biopsy showed enlarged follicles, proliferation of capillary vessels, an increased number of immunoblasts and deposits of PAS positive granules around the immunoblasts. Those histological findings were consistent with those of angio-immunoblastic lymphadenopathy. Although clinical pictures of our case simulated progressive systemic sclerosis and laboratory data suggested dermatomyositis or systemic lupus erythematosus, we diagnosed our case as an overlapping syndrome (type II. Oofuji’s classification), because only some findings of our case corresponded to a few diagnostic criteria of each collagen disease. On the other hand, there is no paper reporting the details of histological pictures of lymphnode of patients with an overlapping syndrome. Furthermore, there is no report that the skin symptoms and laboratory data of angio-immunoblastic lymphadenopathy were suggestive of any collagen disease. Therefore, we considered that our case should be a combined case of angio-immunoblastic lymphadenopathy and overllapping syndrome."},{"@language":"ja","@value":"28才女子例を報告した。本症例は臨床症状, 検査所見から全身性エリテマトーデス, 汎発性鞏皮症, 皮膚筋炎が考えられたが, 各診断基準を十分満足することができず, overlap症候群のII型(大藤の分類)に属すると思われた。リンパ節の組織学的検査ではimmunoblastの増加, 血管の樹枝状増生, PAS陽性物質の沈着, 胚中心のいちじるしい増殖などがみられ, immunoblastic lymphadenopathy, angio-immunoblastic lymphadenopathy, immunodysplasia syndromeを考えたが, 反応性増殖の所見がいちじるしいことよりangio-immunoblastic lymphadenopathyとした。一方, overlap症候群のうちで上記のようなリンパ節所見を呈した症例, あるいは逆にangio-immunoblastic lymphadenopathyで膠原病様症状がみられたという症例の報告がないため, われわれは自験例を標題のごとく2疾患の合併例として報告した。"}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410853646610248706","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257929708"}],"foaf:name":[{"@language":"en","@value":"SHINODA Hidekazu"},{"@language":"ja","@value":"篠田 英和"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Dermatology, Nagasaki University School of Medicine"},{"@language":"ja","@value":"長崎大学医学部皮膚科教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001205739505796","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257928399"},{"@type":"NRID","@value":"9000003750698"}],"foaf:name":[{"@language":"en","@value":"TAKAHASHI Isamu"},{"@language":"ja","@value":"高橋 勇"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Dermatology, Nagasaki University School of Medicine"},{"@language":"ja","@value":"長崎大学医学部皮膚科教室"}]},{"@id":"https://cir.nii.ac.jp/crid/1410853646610248704","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000257929710"}],"foaf:name":[{"@language":"en","@value":"ANAN Sadao"},{"@language":"ja","@value":"阿南 貞雄"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Dermatology, Nagasaki University School of 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Hikotaro"},{"@language":"ja","@value":"吉田 彦太郎"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"長崎大学医学部皮膚科教室"},{"@language":"en","@value":"Department of Dermatology, Nagasaki University School of Medicine"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"03869784"},{"@type":"LISSN","@value":"03869784"},{"@type":"EISSN","@value":"18804047"},{"@type":"NDL_BIB_ID","@value":"000000017954"},{"@type":"ISSN","@value":"03869784"},{"@type":"NCID","@value":"AN00183881"}],"prism:publicationName":[{"@language":"en","@value":"The Nishinihon Journal of Dermatology"},{"@language":"ja","@value":"西日本皮膚科"},{"@language":"en","@value":"Nishinihon J Dermatol"},{"@language":"en","@value":"Nishi Nihon Hifuka"},{"@language":"ja","@value":"西日皮膚"}],"dc:publisher":[{"@language":"en","@value":"Western Division of Japanese Dermatological Association"},{"@language":"ja","@value":"日本皮膚科学会西部支部"}],"prism:publicationDate":"1978","prism:volume":"40","prism:number":"4","prism:startingPage":"629","prism:endingPage":"636"},"reviewed":"false","url":[{"@id":"http://id.ndl.go.jp/bib/1958432"},{"@id":"https://ndlsearch.ndl.go.jp/books/R000000004-I1958432"},{"@id":"https://search.jamas.or.jp/link/ui/1979102778"}],"availableAt":"1978","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=Dermatology","dc:title":"Dermatology"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1360292621604796672","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Angio-immunoblastic lymphadenopathy"}]},{"@id":"https://cir.nii.ac.jp/crid/1361981469986646912","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Mixed connective tissue disease-an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen 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