{"@context":{"@vocab":"https://cir.nii.ac.jp/schema/1.0/","rdfs":"http://www.w3.org/2000/01/rdf-schema#","dc":"http://purl.org/dc/elements/1.1/","dcterms":"http://purl.org/dc/terms/","foaf":"http://xmlns.com/foaf/0.1/","prism":"http://prismstandard.org/namespaces/basic/2.0/","cinii":"http://ci.nii.ac.jp/ns/1.0/","datacite":"https://schema.datacite.org/meta/kernel-4/","ndl":"http://ndl.go.jp/dcndl/terms/","jpcoar":"https://github.com/JPCOAR/schema/blob/master/2.0/"},"@id":"https://cir.nii.ac.jp/crid/1390001204409590016.json","@type":"Article","productIdentifier":[{"identifier":{"@type":"DOI","@value":"10.7887/jcns.18.56_1"}},{"identifier":{"@type":"URI","@value":"https://www.jstage.jst.go.jp/article/jcns/18/1/18_KJ00005133190/_pdf"}},{"identifier":{"@type":"NAID","@value":"110007029865"}},{"identifier":{"@type":"URI","@value":"https://search.jamas.or.jp/link/ui/2009113188"}}],"dc:title":[{"@language":"ja","@value":"ITP合併妊娠による胎児期脳室内出血後水頭症の1例"},{"@language":"en","@value":"Fetal Hydrocephalus following Intracranial Hemorrhage secondary to Maternal Idiopathic Thrombocytopenic Purpura : A Case Report"}],"dc:language":"ja","description":[{"type":"abstract","notation":[{"@language":"en","@value":"Idiopathic thrombocytopenic purpura (ITP) is the most common autoimmune disease in women of childbearing age group. Although maternal antiplatelet antibodies might cross the placenta, they usually do not cause severe bleeding disturbances in the fetus. Occurrence of fetal intracranial hemorrhage is extremely uncommon. We report a case of a fetus developed intracranial hemorrhage at 34 weeks of gestational age, possibly secondary to maternal ITP. The hemorrhage was intra and periventricular, with the development of posthemorrhagic hydrocephalus. Cesarean section was performed at 35 weeks of gestation because of progression of hydrocephalus. In order to control hydrocephalus, Ommaya's reservoir was placed in the right anterior horn three days after birth, considering the poor general condition of the infant girl. Her level of consciousness suddenly decreased the following day. CT scan showed recurrence of intraventricular hemorrhage. She underwent platelet transfusion and repeated aspiration of bloody cerebrospinal fluid from the reservoir. Following this, her platelet count normalized gradually. Ventriculoperitoneal shunt was carried out successfully 2 months after birth. Thereafter she did not experience any hemorrhagic episodes. The problem of ITP of the mother in relation to pregnancy and its effects on the fetus and the newborn infant are discussed in the present report."},{"@language":"ja","@value":"ITP合併妊娠による胎児脳室内出血後水頭症の1例を報告する.胎生34週に母体超音波にて胎児脳室内出血と頭囲拡大がみられ,35週に帝王切開にて出生.出生時,児の血小板数は1.7×10^4/μlで,血小板輸血,ガンマグロブリン大量療法,ステロイド療法を行った.生後3日目に血小板数は7.6×10^4/μlに増加し,水頭症に対しOmmayaリザーバー留置術を施行したところ,再び脳室内出血をきたした.保存的治療にて良好に経過し,脳室-腹腔シャント術施行後,退院となった.新生児脳室内出血の報告は散見されるが,ITP合併妊娠による胎児期脳室内出血後水頭症の報告は非常にまれである.ITP合併妊娠による胎児および新生児の管理法について,脳神経外科医の視点から考察を行った."}],"abstractLicenseFlag":"disallow"}],"creator":[{"@id":"https://cir.nii.ac.jp/crid/1410001204409590023","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"伊藤 英道"},{"@language":"en","@value":"Ito Hidemichi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine, Yokohama City Seibu Hospital"},{"@language":"ja","@value":"聖マリアンナ医科大学横浜市西部病院脳神経外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204409590021","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"榊原 陽太郎"},{"@language":"en","@value":"Sakakibara Yohtaro"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine, Yokohama City Seibu Hospital"},{"@language":"ja","@value":"聖マリアンナ医科大学横浜市西部病院脳神経外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204409590022","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"平本 準"},{"@language":"en","@value":"Hiramoto Jun"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"聖マリアンナ医科大学脳神経外科"},{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204409590017","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000005452791"}],"foaf:name":[{"@language":"ja","@value":"吉田 浩"},{"@language":"en","@value":"Yoshida Hiroshi"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine, Yokohama City Seibu Hospital"},{"@language":"ja","@value":"聖マリアンナ医科大学横浜市西部病院脳神経外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204409590019","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000006879191"}],"foaf:name":[{"@language":"ja","@value":"酒井 晃治"},{"@language":"en","@value":"Sakai Kouji"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine, Yokohama City Seibu Hospital"},{"@language":"ja","@value":"聖マリアンナ医科大学横浜市西部病院脳神経外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204409590016","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"小野寺 英孝"},{"@language":"en","@value":"Onodera Hidetaka"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine, Yokohama City Seibu Hospital"},{"@language":"ja","@value":"聖マリアンナ医科大学横浜市西部病院脳神経外科"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204409155459","@type":"Researcher","personIdentifier":[{"@type":"NRID","@value":"9000006879193"}],"foaf:name":[{"@language":"ja","@value":"和久井 大輔"},{"@language":"en","@value":"Wakui Daisuke"}],"jpcoar:affiliationName":[{"@language":"ja","@value":"聖マリアンナ医科大学横浜市西部病院脳神経外科"},{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine, Yokohama City Seibu Hospital"}]},{"@id":"https://cir.nii.ac.jp/crid/1410001204409590020","@type":"Researcher","foaf:name":[{"@language":"ja","@value":"田口 芳雄"},{"@language":"en","@value":"Taguchi Yoshio"}],"jpcoar:affiliationName":[{"@language":"en","@value":"Department of Neurosurgery, St. Marianna University School of Medicine, Yokohama City Seibu Hospital"},{"@language":"ja","@value":"聖マリアンナ医科大学横浜市西部病院脳神経外科"}]}],"publication":{"publicationIdentifier":[{"@type":"PISSN","@value":"0917950X"},{"@type":"LISSN","@value":"0917950X"},{"@type":"EISSN","@value":"21873100"},{"@type":"NCID","@value":"AN10380506"}],"prism:publicationName":[{"@language":"en","@value":"Japanese Journal of Neurosurgery"},{"@value":"脳神経外科ジャーナル"},{"@language":"en","@value":"Jpn J Neurosurg"},{"@value":"脳外誌"}],"dc:publisher":[{"@language":"en","@value":"The Japanese Congress of Neurological Surgeons"},{"@language":"ja","@value":"一般社団法人日本脳神経外科コングレス"}],"prism:publicationDate":"2009","prism:volume":"18","prism:number":"1","prism:startingPage":"56","prism:endingPage":"61"},"reviewed":"false","dcterms:accessRights":"http://purl.org/coar/access_right/c_abf2","url":[{"@id":"https://www.jstage.jst.go.jp/article/jcns/18/1/18_KJ00005133190/_pdf"},{"@id":"https://search.jamas.or.jp/link/ui/2009113188"}],"availableAt":"2009","foaf:topic":[{"@id":"https://cir.nii.ac.jp/all?q=idiopathic%20thrombocytopenic%20purpura","dc:title":"idiopathic thrombocytopenic purpura"},{"@id":"https://cir.nii.ac.jp/all?q=in%20utero%20intracranial%20hemorrhage","dc:title":"in utero intracranial hemorrhage"},{"@id":"https://cir.nii.ac.jp/all?q=fetal%20hydrocephalus","dc:title":"fetal hydrocephalus"}],"relatedProduct":[{"@id":"https://cir.nii.ac.jp/crid/1361981470930275712","@type":"Article","relationType":["references"],"jpcoar:relatedTitle":[{"@value":"Fetal Hydrocephalus in a Pregnancy Complicated by 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